Protein Alignment Rift and SLC52A3

DIOPT Version :9

• Sequence 1: NP_651901.3
• Gene: Rift / 43756
• FlyBaseID: FBgn0039882
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_001357014.1
• Gene: SLC52A3 / 113278
• HGNCID: 16187
• Length: 469
• Species: Homo sapiens
• Alignment Length: 469
• Identity: 171/469 - (36%)
• Similarity: 246/469 - (52%)
• Gaps: 66/469 - (14%)

  Fly    73 SWLVDVLAIFFGIGTWLGVNGTFIQLPLLVDEAPEGWSLPSYLSVMVQIGNLGPLLYTAIQKYSP 137
            ::|:.:|...||:|:|:.:||.:::|||||.|.||||.|||||:|::|:.|:||||.|.:..:.|
Human     2 AFLMHLLVCVFGMGSWVTINGLWVELPLLVMELPEGWYLPSYLTVVIQLANIGPLLVTLLHHFRP 66

  Fly   138 KKLNDGWTIHGVLLVGAISCLLTAFFYNQTASVAGTDHSLALFLLTCFTALNACTSSVLFMPYMG 202
            ..|::...|..:|.||.::|::.||.:|.|:.|....||:|..:||.|.||..|||||.|:|:|.
Human    67 SCLSEVPIIFTLLGVGTVTCIIFAFLWNMTSWVLDGHHSIAFLVLTFFLALVDCTSSVTFLPFMS 131

  Fly   203 RFKEQYMVTYFIGEGLSGLLPSVTALIQGIGESGDCVLVNVTESGEE------------------ 249
            |....|:.|:|:|||||||||::.||.||   ||....|||||..:.
Human   132 RLPTYYLTTFFVGEGLSGLLPALVALAQG---SGLTTCVNVTEISDSVPSPVPTRETDIAQGVPR 193

  Fly   250 --VYAL------------RKTPPRFDTRVFFLILFALMVLAYVGYALLNSLP------------- 287
              |.||            |..|..|...||||:|..:|....|.:.:|...|
Human   194 ALVSALPGMEAPLSHLESRYLPAHFSPLVFFLLLSIMMACCLVAFFVLQRQPRCWEASVEDLLND 258

  Fly   288 ------LARRE------YAQVTVSEGNKYVYGEADNQPKAEKLSKGQYTYLLLLIGAISLFSNGM 340
                  :..||      ...|..|:|..|:      :.||.........::..|:..::..:|||
Human   259 QVTLHSIRPREENDLGPAGTVDSSQGQGYL------EEKAAPCCPAHLAFIYTLVAFVNALTNGM 317

  Fly   341 FGSIQSYSSAPYGSQAYHLAATLSVIANPVACFMAMFLHFTSLRIITVLSILAGLLTSYVFTTAA 405
            ..|:|:||...||..|||||||||::|||:|..::|||...||..:.|||:|......|....|.
Human   318 LPSVQTYSCLSYGPVAYHLAATLSIVANPLASLVSMFLPNRSLLFLGVLSVLGTCFGGYNMAMAV 382

  Fly   406 LSPLPPLHDQTVGAVLVVTAWTLLVGIVSYTKLGITTVMRAQGGQSLVWVGAITQLGSAIGAVAI 470
            :||.|.|.....|.||:|.:|.|..|.:||.|:.:..|:|.....:|:|.||..||||.:||:.:
Human   383 MSPCPLLQGHWGGEVLIVASWVLFSGCLSYVKVMLGVVLRDLSRSALLWCGAAVQLGSLLGALLM 447

  Fly   471 FFAINYSDLFQAAE 484
            |..:|...||.:|:
Human   448 FPLVNVLRLFSSAD 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rift	NP_651901.3	DUF1011	320..418	CDD:283816	38/97 (39%)
SLC52A3	NP_001357014.1	DUF1011	298..395	CDD:310675	38/96 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148947
Domainoid	1	1.000	173	1.000	Domainoid score	I3708
eggNOG	1	0.900	-	-		E1_KOG4255
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12324
Inparanoid	1	1.050	283	1.000	Inparanoid score	I2878
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52392
OrthoDB	1	1.010	-	-		D356719at33208
OrthoFinder	1	1.000	-	-		FOG0004349
OrthoInspector	1	1.000	-	-		oto89201
orthoMCL	1	0.900	-	-		OOG6_105349
Panther	1	1.100	-	-	O	PTHR12929
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3974
SonicParanoid	1	1.000	-	-		X1135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800