Protein Alignment Loxl1 and Marco

DIOPT Version :10

• Sequence 1: NP_524607.1
• Gene: Loxl1 / 43712
• FlyBaseID: FBgn0039848
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: NP_034896.1
• Gene: Marco / 17167
• MGIID: 1309998
• Length: 518
• Species: Mus musculus
• Alignment Length: 469
• Identity: 83/469 - (17%)
• Similarity: 158/469 - (33%)
• Gaps: 138/469 - (29%)

  Fly    14 TSGNAQRNNKEGSSHKLPSLESWFGKKTTSEATAQNQIVGDNPQNNSVGNYFNQNLNEDHHDHQF 78
            ::||...|::.......|..::.|.::.|.          |:|....           :.||.|
Mouse    29 STGNTAENHRHPIPDDPPLFQACFPRRATV----------DDPLPAL-----------EIHDLQ- 71

  Fly    79 AQQNPDNALDNSQTWHNLDRIHQNFQTMDMQ------PYQEYQDNNESGWVDLNNDNQFQQPDNN 137
                 |..:.:|:.:|.   ...|.:...:|      |.:|..|:.....|     |.|:.|.:.
Mouse    72 -----DEPISSSKFFHT---AVNNLELEVLQPSIPDAPAEEDLDSTVKSEV-----NSFESPVSQ 123

  Fly   138 DPNANDLNLWNMETGPGQVFEAPVLPAIPWNNDDNFNDNFTEDDAIS----QISFDSEIKSETDS 198
            ..:.:.:    .|...|...:..:..|:..:::.:.|...::||:..    .::.|.|...:.:.
Mouse   124 QFSTDGI----FEAFSGDSVQVDIDSALDEDSESSLNQKVSQDDSADDSALSLTADDETCLDNND 184

  Fly   199 MVSRKR--KRNREDAQNSYDKKKRIRDENETFFKSQKLTHENLLNQNILNEAHFRTAVKLVLRPC 261
            :.||..  |:..|....|..:..||:|..:...|..::|.    ....|..:|.:..:::.|...
Mouse   185 ISSRYNLGKQLGEGGFGSVFEGIRIQDGLQVAVKFAQMTP----RMRDLCSSHDQPPLEITLASM 245

  Fly   262 FSN----LRIIKVYYTNCSSEQVFR--------------CLADFERDKADIITEKD--------- 299
            .|:    ..||::.     ..|||:              .|..|.:.|..::||:.
Mouse   246 ASSGSRCANIIQLL-----DWQVFKDHYVMVMERPTPSMDLEAFLQLKGGVLTEQTAQTIMGQAV 305

  Fly   300 ---------NLKRRDMNLAKLKTRMDETE-KVYD---------DAQADLDNKKVGIPPGTLASGC 345
                     .:..||:.|..|....:..| |:.|         .|.:.....:..:||.....||
Mouse   306 HAANVCCYREVFHRDIKLQNLLVNPNTLEVKLIDFGCGDYMIESAYSTFSGTEAYMPPEFYKRGC 370

  Fly   346 FRAKQKYETVAFEHGAGELQY-----EFSKQYRIASRLTAYGGWFYPDARNLLQHNW------QF 399
            :.||.     |..:..|.|.:     :|...|.:          :|      |:|:|      |.
Mouse   371 YHAKP-----ATVYSLGVLLFTLLHGDFPTTYDL----------YY------LEHDWSKFTLSQE 414

  Fly   400 LCDNAGPDIEQLKE 413
            .||.....::|:.|
Mouse   415 CCDLMWACLQQIPE 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Loxl1	NP_524607.1	SR	50..136	CDD:214555	17/91 (19%)
		Lysyl_oxidase	149..351	CDD:460102	46/253 (18%)
Marco	NP_034896.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	147..426		55/308 (18%)
		Collagen	149..198	CDD:460189	8/48 (17%)
		gly_rich_SclB	<175..>401	CDD:468478	45/249 (18%)
		SR	423..518	CDD:214555	2/6 (33%)