Protein Alignment Loxl1 and Loxl1

DIOPT Version :10

• Sequence 1: NP_524607.1
• Gene: Loxl1 / 43712
• FlyBaseID: FBgn0039848
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: NP_034859.2
• Gene: Loxl1 / 16949
• MGIID: 106096
• Length: 607
• Species: Mus musculus
• Alignment Length: 267
• Identity: 98/267 - (36%)
• Similarity: 142/267 - (53%)
• Gaps: 43/267 - (16%)

  Fly    92 SQGTEHGDSRKYPWG--MVGTLCRGTE--RRLADCIRESHYPNLCNARNHNVSIAACVSHSADLE 152
            |||.|...:::   |  .||::.|..:  |.|.|.:.:.:|
Mouse   374 SQGGERNGAQQ---GRLSVGSVYRPNQNGRGLPDLVPDPNY------------------------ 411

  Fly   153 IGLVDIERTARLEAVPMSRLTCAMEEHCVSADAYEIRRTNPHAARILLRFSVKASNVGTADVSPY 217
                 ::.:..::...:..|.||.||.|:::.||....|: :..|:||||..:..|.||||..|.
Mouse   412 -----VQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATD-YDLRVLLRFPQRVKNQGTADFLPN 470

  Fly   218 ANYKEWVWHQCHRHYHSMNVFATFDVYDLNY-RKVAQGHKASFCLMDSECRPGVRQKYTCGNTTQ 281
            .....|.||.||:|||||:.|:.:|:.|.:. :|||:||||||||.||.|..|..::|.|.:.||
Mouse   471 RPRHTWEWHSCHQHYHSMDEFSHYDLLDASTGKKVAEGHKASFCLEDSTCDFGNLKRYACTSHTQ 535

  Fly   282 GISVGCADTYTDVLDCQWVDVTRV-PINRRYILRVALNPEYKLGEISFENNGAECLLDYTGVRQT 345
            |:|.||.|||...:||||:|:|.| |.|  |||:|.:||:|.:.|..|.||...|.:.|||...:
Mouse   536 GLSPGCYDTYNADIDCQWIDITDVQPGN--YILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVS 598

  Fly   346 TRIFNCR 352
            |.  ||:
Mouse   599 TT--NCK 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Loxl1	NP_524607.1	SR	50..136	CDD:214555	12/47 (26%)
		Lysyl_oxidase	149..351	CDD:460102	84/203 (41%)
Loxl1	NP_034859.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..111
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	237..323
		Interaction with FBLN5. /evidence=ECO:0000269|PubMed:14745449	334..402		9/31 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	362..388		4/13 (31%)
		Lysyl-oxidase like	403..607		77/205 (38%)
		Lysyl_oxidase	403..602	CDD:460102	75/200 (38%)