Protein Alignment chp and lrrc4.1

DIOPT Version :10

• Sequence 1: NP_001263137.1
• Gene: chp / 43690
• FlyBaseID: FBgn0267435
• Length: 1338
• Species: Drosophila melanogaster
• Sequence 2: XP_005164844.1
• Gene: lrrc4.1 / 565021
• ZFINID: ZDB-GENE-041210-129
• Length: 858
• Species: Danio rerio
• Alignment Length: 712
• Identity: 154/712 - (21%)
• Similarity: 237/712 - (33%)
• Gaps: 255/712 - (35%)

  Fly   450 ELEDLQITRASLS----GIQSHAFKHVRGLKRLDFSENGISSIENDAFHEIGHSLISLKMSHGYS 510
            :|..:..||..|:    ||.|..       :.|:..||.|.|::.|:|..:.|
Zfish    53 QLSKVVCTRRGLTRVPPGIPSTT-------RHLNLMENAIESVQVDSFRNLHH------------ 98

  Fly   511 GSALPAEPLRHLTSLQELDFSNNHISSMSDTSFHFLKNLRLLELHDNRIEQVLKGTFQGDIHSKL 575
                          |:.|....|.|..:...:|..|.||..|||.|||:..|..|.|  :..|||
Zfish    99 --------------LEVLQLGRNAIRQIEVGAFSGLTNLNTLELFDNRLTVVPSGAF--EYLSKL 147

  Fly   576 EEISLRFNHLTSISQHTFFDLEALRKLHLDDNKIDKIERRAFMNLDELEYLSLRGNKINNLADES 640
            .|:.||.|.:.||..:.|..:.:|.:|.|.:             |.:|||:|          |.:
Zfish   148 RELWLRNNPIESIPSYAFNRVPSLMRLDLGE-------------LRKLEYIS----------DGA 189

  Fly   641 FQNLPKLEILDMAF----NQLPNFNFDYFDQVGTLSNLNVNVSHNQIRQLMYNSSWSGRNEHGGM 701
            |:.|..|:.|::..    .::|||.    ..||
Zfish   190 FEGLVNLKYLNLGMCNIRGEMPNFT----PLVG-------------------------------- 218

  Fly   702 YHSNIKILDLSHNNISIIHPGYFRPAEISLTHLHLGYNSLMNTTRDVFGNMPHLQWLDLSYNWIH 766
                ::.|::|.|....|.||.||           |.:||...            |:..|.  |.
Zfish   219 ----LEELEISENLFPEIKPGSFR-----------GLSSLKKL------------WIMNSQ--IG 254

  Fly   767 ELDFDAFKNTKQLQLVFFGHNYLSDIPQDIFKPVQGLRIVDFSHNHLRGLPDNLFYNGGMEKLDV 831
            .::.:||.:...|..:...||.||.:|.|::.|::.|..:...||.         :|.|.:.|.:
Zfish   255 LIERNAFDDLASLVELNLAHNNLSSLPHDLYTPLKYLVELHLHHNP---------WNCGCDSLWL 310

  Fly   832 SHNMMLKIPSSSLSSLAALTLC-ELHLSNNFISTIHSMDLSNKFRSLRYLDISYNYLLRIDDAVF 895
            :..:...||::|       |.| ..|      |..|.     :.|.|..||......::......
Zfish   311 ARWLREYIPTNS-------TCCGRCH------SPAHM-----RGRQLVELDRGDTGAMQCSAPFI 357

  Fly   896 ATMPKLAVLDLSHNRDLKVMDKSFMGLENSLIKLGLENISLSTVPEIRLKYLREFRLGYNELPSI 960
            |..|          |||                    |||...|.|::.:
Zfish   358 ADAP----------RDL--------------------NISAERVAELKCR--------------- 377

  Fly   961 PQELAHNMSNLRMLDLSNNDLTNVPLMTQALPHLRRLMLSGNPITSLNNNSFDGVN---EDLEML 1022
                ...||.:|.|      |.|..::|.|..|.|        :|.||:.:.:..|   .|..|
Zfish   378 ----TAAMSAVRWL------LPNGTILTHASSHPR--------LTVLNDGTLNFSNVLAGDTGM- 423

  Fly  1023 DISNFRLHYFEYGCLDSLPHLRSLKLTAY-----SHLEHFNIPHLLRHHYNIRQLWIEAPQPFTR 1082
                       |.|:.|.....| ..:||     :.|...|:.:.......:.....|.|:|.|.
Zfish   424 -----------YTCMVSNAAGNS-NASAYLNVSAAELNTSNLSYFTTVTVEVLSPTSEMPKPKTT 476

  Fly  1083 IVKKGSGPT-----QEMQTLQLGNPTDLQREME------GHLP-SKLTNITFSGPQFTNLNE 1132
            ....|:..|     ...|.:.:..||.|.:..:      ..:| ||:|......|..|:|:|
Zfish   477 TTTAGASTTTTASPSVFQPVFISTPTVLLQSTDTPPSRPSVIPGSKVTTGKPPNPASTSLDE 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chp	NP_001263137.1	LRR	<84..320	CDD:443914
		leucine-rich repeat	84..103	CDD:275380
		leucine-rich repeat	104..128	CDD:275380
		leucine-rich repeat	129..152	CDD:275380
		leucine-rich repeat	153..177	CDD:275380
		leucine-rich repeat	178..201	CDD:275380
		leucine-rich repeat	202..226	CDD:275380
		leucine-rich repeat	227..250	CDD:275380
		leucine-rich repeat	251..279	CDD:275380
		leucine-rich repeat	280..326	CDD:275380
		leucine-rich repeat	327..348	CDD:275380
		leucine-rich repeat	352..375	CDD:275380
		PPP1R42	355..564	CDD:455733	30/117 (26%)
		leucine-rich repeat	376..401	CDD:275380
		leucine-rich repeat	426..450	CDD:275378	154/712 (22%)
		leucine-rich repeat	451..474	CDD:275380	7/26 (27%)
		LRR_8	473..559	CDD:404697	21/85 (25%)
		leucine-rich repeat	475..524	CDD:275380	8/48 (17%)
		leucine-rich repeat	500..519	CDD:275380	0/18 (0%)
		leucine-rich repeat	525..548	CDD:275380	6/22 (27%)
		LRR	<540..>834	CDD:443914	71/297 (24%)
		leucine-rich repeat	549..574	CDD:275380	10/24 (42%)
		leucine-rich repeat	575..598	CDD:275380	8/22 (36%)
		leucine-rich repeat	599..622	CDD:275380	4/22 (18%)
		leucine-rich repeat	623..646	CDD:275380	7/22 (32%)
		leucine-rich repeat	647..730	CDD:275380	15/86 (17%)
		leucine-rich repeat	648..673	CDD:275380	6/28 (21%)
		leucine-rich repeat	674..705	CDD:275380	0/30 (0%)
		LRR	<730..1081	CDD:443914	71/359 (20%)
		leucine-rich repeat	731..754	CDD:275380	3/22 (14%)
		leucine-rich repeat	755..778	CDD:275380	5/22 (23%)
		leucine-rich repeat	779..802	CDD:275380	8/22 (36%)
		leucine-rich repeat	803..823	CDD:275380	3/19 (16%)
		leucine-rich repeat	852..876	CDD:275380	4/24 (17%)
		leucine-rich repeat	877..900	CDD:275380	4/22 (18%)
		leucine-rich repeat	901..925	CDD:275380	3/23 (13%)
		leucine-rich repeat	926..946	CDD:275380	5/19 (26%)
		leucine-rich repeat	947..970	CDD:275380	1/22 (5%)
		leucine-rich repeat	971..993	CDD:275380	6/21 (29%)
		leucine-rich repeat	994..1014	CDD:275380	4/19 (21%)
		leucine-rich repeat	1019..1042	CDD:275380	4/22 (18%)
lrrc4.1	XP_005164844.1	LRRNT	43..72	CDD:396168	5/18 (28%)
		leucine-rich repeat	54..73	CDD:275380	6/18 (33%)
		leucine-rich repeat	75..98	CDD:275380	7/29 (24%)
		LRR	78..>300	CDD:443914	79/337 (23%)
		leucine-rich repeat	99..122	CDD:275380	6/22 (27%)
		leucine-rich repeat	123..146	CDD:275380	10/24 (42%)
		leucine-rich repeat	147..170	CDD:275380	8/22 (36%)
		leucine-rich repeat	171..195	CDD:275380	11/46 (24%)
		leucine-rich repeat	196..218	CDD:275380	5/25 (20%)
		leucine-rich repeat	219..242	CDD:275380	9/33 (27%)
		leucine-rich repeat	243..266	CDD:275380	6/36 (17%)
		leucine-rich repeat	267..288	CDD:275380	7/20 (35%)
		LRRCT	299..>339	CDD:214507	13/66 (20%)
		Ig	359..443	CDD:472250	31/159 (19%)
		Ig strand B	372..376	CDD:409353	1/3 (33%)
		Ig strand C	383..387	CDD:409353	1/3 (33%)
		Ig strand E	409..413	CDD:409353	0/3 (0%)
		Ig strand F	423..428	CDD:409353	3/16 (19%)
		Ig strand G	436..439	CDD:409353	0/2 (0%)