Protein Alignment chp and CG4950

DIOPT Version :10

• Sequence 1: NP_001263137.1
• Gene: chp / 43690
• FlyBaseID: FBgn0267435
• Length: 1338
• Species: Drosophila melanogaster
• Sequence 2: NP_648855.2
• Gene: CG4950 / 39783
• FlyBaseID: FBgn0036587
• Length: 574
• Species: Drosophila melanogaster
• Alignment Length: 706
• Identity: 144/706 - (20%)
• Similarity: 254/706 - (35%)
• Gaps: 248/706 - (35%)

  Fly   525 LQELDFSNNHISSMSDTSFHFLKNLRLLELHDNRIEQVLKGTFQGDIHSKLEEISLRFNHLTSIS 589
            |:.||.||.:|..::..:|....||..|.|..|.:..:....|.|  .:.|..:.|.:|.::|:|
  Fly    96 LKTLDVSNTNILELTRNAFSAASNLTYLNLAYNNLTSIQTSVFIG--ANVLMRLDLSYNEISSLS 158

  Fly   590 QHTFFDLEALRKLHLDDNKIDKIERRAFMNLDELEYLSLRGNKINNLADESFQNLPKLEILDMAF 654
            .:.|..|..:.:::|..|.:.::....|.:.:.||.:|..||.:.::..|.|:|:.:
  Fly   159 VNAFCGLHTISQIYLTGNLLKELHNDIFKDNEYLEKVSFEGNLLTSIQPEVFRNMRR-------- 215

  Fly   655 NQLPNFNFDYFDQVGTLSNLNVNVSHNQIRQLMYNSSWSGRNEHGGMYHSNIKILDLSHNNISII 719
                                                               ||.::||:|.:..|
  Fly   216 ---------------------------------------------------IKEVNLSNNRLIFI 229

  Fly   720 HPGYFRPAEISLTHLHLGYNSLMN---TTRDVFGNMPHLQWLDLSYNWIHELDFDAFKNTKQLQL 781
            ||..|..| .||.:|.|.||.|.|   |.:::                :|:|..|
  Fly   230 HPDTFADA-ASLENLVLSYNELKNFQLTEKNI----------------VHQLHLD---------- 267

  Fly   782 VFFGHNYLSDIPQDIFKPVQGLRIVDFSHNHLRGLPDNLFYNGGM--EKLDVSHNMMLKIPSSSL 844
                :|||:::      .:...|.|..|||.:    ..||.:..:  |.||:|.|.:     ||:
  Fly   268 ----NNYLTNL------TINATRFVRASHNQI----SELFLHQSLHIETLDLSANKL-----SSI 313

  Fly   845 SSLAALTLCELHLSNNFISTIHSMDLSNKFRSLRYLDISYNYLLRIDDAVFATMPKLAVLDLSHN 909
            |::..:|              |.:          |||:|.|.:..::.:.|:.:.:|..|:|...
  Fly   314 SNITNIT--------------HML----------YLDVSDNPIGPLNISTFSQLKRLRGLNLRGT 354

  Fly   910 RDLKVMDKSFMGLENSLIKLGLENISLSTVPEIRLKYLREFRLGYNELPSIPQELAHNMSNLRML 974
                       |:..  :|.|:.:         :.|||.|                        |
  Fly   355 -----------GIRE--LKFGMFS---------KQKYLEE------------------------L 373

  Fly   975 DLSNNDLT--NVPLMTQALPHLRRLMLSGNPITSL-NNNSFDGVNEDLEMLDISNFRLHYFEYGC 1036
            |||.|:||  |:.:....|.:|::.::.||.:|.| .|.:|......|:.|.:|..|     :.|
  Fly   374 DLSFNNLTILNLDMFVPYLTNLKKFLIDGNGLTELQGNRTFSEAFPQLQKLGVSRNR-----FNC 433

  Fly  1037 LDSLPHLRSLKLTAYSHLEHFNIPHLLRHH--YNIRQLWIEAPQPFTRI-----VKKGSGPTQEM 1094
                           |:|.|..||..|...  .||        :|.|.:     ::..|..:|..
  Fly   434 ---------------SYLHHLLIPPSLPESVVLNI--------EPDTNLDETPHIRDVSCISQSQ 475

  Fly  1095 QTLQLGNPTDLQREMEGHLPSKLTNITFSGPQFTNLNERILRGMRSPYLYMQLFNTSLQALPPNF 1159
            :.:. .:.|..:.::|..:......:...|....||...:        .:||:|...:..|
  Fly   476 EVVN-ASFTAEESKLESQIQMLSKQLDIVGSHSKNLELHL--------AFMQIFAYVMGGL---- 527

  Fly  1160 FKYMGRVRNISLDIRYHNRNLKKIPNPNTG-----AVPYLPNSVFLTDLKMSHTDL 1210
             ..:|.|..|:|  ||       :.|..:|     ::.:..|:....:|.:...||
  Fly   528 -VLVGVVSLITL--RY-------LKNQRSGRYDRSSIVFRSNATMEANLTLGSEDL 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chp	NP_001263137.1	LRR	<84..320	CDD:443914
		leucine-rich repeat	84..103	CDD:275380
		leucine-rich repeat	104..128	CDD:275380
		leucine-rich repeat	129..152	CDD:275380
		leucine-rich repeat	153..177	CDD:275380
		leucine-rich repeat	178..201	CDD:275380
		leucine-rich repeat	202..226	CDD:275380
		leucine-rich repeat	227..250	CDD:275380
		leucine-rich repeat	251..279	CDD:275380
		leucine-rich repeat	280..326	CDD:275380
		leucine-rich repeat	327..348	CDD:275380
		leucine-rich repeat	352..375	CDD:275380
		PPP1R42	355..564	CDD:455733	12/38 (32%)
		leucine-rich repeat	376..401	CDD:275380
		leucine-rich repeat	426..450	CDD:275378
		leucine-rich repeat	451..474	CDD:275380
		LRR_8	473..559	CDD:404697	12/33 (36%)
		leucine-rich repeat	475..524	CDD:275380
		leucine-rich repeat	500..519	CDD:275380
		leucine-rich repeat	525..548	CDD:275380	7/22 (32%)
		LRR	<540..>834	CDD:443914	62/298 (21%)
		leucine-rich repeat	549..574	CDD:275380	6/24 (25%)
		leucine-rich repeat	575..598	CDD:275380	7/22 (32%)
		leucine-rich repeat	599..622	CDD:275380	3/22 (14%)
		leucine-rich repeat	623..646	CDD:275380	8/22 (36%)
		leucine-rich repeat	647..730	CDD:275380	10/82 (12%)
		leucine-rich repeat	648..673	CDD:275380	0/24 (0%)
		leucine-rich repeat	674..705	CDD:275380	0/30 (0%)
		LRR	<730..1081	CDD:443914	78/360 (22%)
		leucine-rich repeat	731..754	CDD:275380	8/25 (32%)
		leucine-rich repeat	755..778	CDD:275380	3/22 (14%)
		leucine-rich repeat	779..802	CDD:275380	3/22 (14%)
		leucine-rich repeat	803..823	CDD:275380	7/19 (37%)
		leucine-rich repeat	852..876	CDD:275380	1/23 (4%)
		leucine-rich repeat	877..900	CDD:275380	6/22 (27%)
		leucine-rich repeat	901..925	CDD:275380	4/23 (17%)
		leucine-rich repeat	926..946	CDD:275380	2/19 (11%)
		leucine-rich repeat	947..970	CDD:275380	2/22 (9%)
		leucine-rich repeat	971..993	CDD:275380	9/23 (39%)
		leucine-rich repeat	994..1014	CDD:275380	7/20 (35%)
		leucine-rich repeat	1019..1042	CDD:275380	5/22 (23%)
CG4950	NP_648855.2	LRR	96..411	CDD:443914	104/491 (21%)
		leucine-rich repeat	96..119	CDD:275380	7/22 (32%)
		leucine-rich repeat	120..143	CDD:275380	6/24 (25%)
		leucine-rich repeat	144..167	CDD:275380	7/22 (32%)
		leucine-rich repeat	168..191	CDD:275380	3/22 (14%)
		leucine-rich repeat	192..215	CDD:275380	8/22 (36%)
		leucine-rich repeat	216..239	CDD:275380	10/23 (43%)
		leucine-rich repeat	240..299	CDD:275380	21/98 (21%)
		leucine-rich repeat	300..321	CDD:275380	9/39 (23%)
		leucine-rich repeat	322..345	CDD:275380	6/32 (19%)
		leucine-rich repeat	346..365	CDD:275380	6/31 (19%)
		leucine-rich repeat	370..394	CDD:275380	11/47 (23%)
		leucine-rich repeat	395..420	CDD:275380	7/24 (29%)