Protein Alignment chp and lrrc4c

DIOPT Version :10

• Sequence 1: NP_001263137.1
• Gene: chp / 43690
• FlyBaseID: FBgn0267435
• Length: 1338
• Species: Drosophila melanogaster
• Sequence 2: XP_002938986.1
• Gene: lrrc4c / 100188921
• XenbaseID: XB-GENE-5772259
• Length: 639
• Species: Xenopus tropicalis
• Alignment Length: 752
• Identity: 147/752 - (19%)
• Similarity: 257/752 - (34%)
• Gaps: 260/752 - (34%)

  Fly   457 TRASL----SGIQSHAFKHVRGLKRLDFSENGISSIENDAFHEIGHSLISLKMSHGYSGSALPAE 517
            ||.:|    .||.::.       ::|:..||.|..|:.|:|
 Frog    63 TRRNLREVPDGISTNT-------RQLNLHENQIQIIKVDSF------------------------ 96

  Fly   518 PLRHLTSLQELDFSNNHISSMSDTSFHFLKNLRLLELHDNRIEQVLKGTFQGDIHSKLEEISLRF 582
              :||..|:.|..|.|||.::...:|:.|.||..|||.|||:..:..|.|  :..|||:|:.||.
 Frog    97 --KHLRHLEVLQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAF--EYLSKLKELWLRN 157

  Fly   583 NHLTSISQHTFFDLEALRKLHLDDNK-IDKIERRAFMNLDELEYLSLRGNKINNLADESFQNLPK 646
            |.:.||..:.|..:.:||:|.|.:.| :..|...||..|..|:||:|   .:.||.|  ..||..
 Frog   158 NPIESIPSYAFNRIPSLRRLDLGEMKRLSYISEGAFEGLSNLKYLNL---GMCNLRD--IPNLTP 217

  Fly   647 LEILDMAFNQLPNFNFDYFDQVGTLSNLNVNVSHNQIRQLMYNSSWSGRNEHGGMYHSNIKILDL 711
            |..||.                                                        |||
 Frog   218 LVKLDE--------------------------------------------------------LDL 226

  Fly   712 SHNNISIIHPGYFRPAEISLTHLHLGYNSLMNTTRDVFGNMPHLQWLDLSYNWIHELDFDAFKNT 776
            |.|::|::.||.|:                         .:.|||.|.:.::.|..::.:||.:.
 Frog   227 SGNHLSVLRPGSFQ-------------------------GLTHLQKLWIMHSQIQVIERNAFDDL 266

  Fly   777 KQLQLVFFGHNYLSDIPQDIFKPVQGLRIVDFSHNHLRGLPDNLFYNGGMEKL------------ 829
            :.|..:...||.|:.:|.|:|.|:..|:.:...||......|.|:.:..::::
 Frog   267 QSLVELNLAHNNLTLLPHDLFTPLHNLQRIQLHHNPWNCNCDILWLSWWLKEIVTTGSTCCARCS 331

  Fly   830 -----------DVSHNM------MLKIPSSSLS---SLAALTLCELHLSNNFISTI--------H 866
                       ::.||.      ::..|.:.|:   .:||...|....|..::|.|        |
 Frog   332 TPPSLKGTHIAELDHNYFTCYAPVIVEPPADLNVTEGMAAELKCRASTSLTYVSWITPNGTIMTH 396

  Fly   867 SMDLSNKFRSLRYLDISYNYLLRIDDAVFATMPKLAVLDLSHNRDLKVMDKSFMGLENSLIKLGL 931
            .                 :|.:||......|:         :..::.|.|   .||...::....
 Frog   397 G-----------------SYKVRISVLNDGTL---------NFTNVTVRD---TGLYTCIVSNSA 432

  Fly   932 ENISLSTVPEIRLKYLREFRLGYNELPSIPQELAH-----------NMSNLRMLDLSNNDLTNVP 985
            .|.:.|....:...     ..||....::..|...           ::....::|....:.| ..
 Frog   433 GNTTASATLNVTAS-----DTGYTYFSTVTVETMEPSQDEARTTETHVGPTPVIDWETTNAT-TS 491

  Fly   986 LMTQALPHLRRLMLSGNPITSLNNNSFDGVNEDLEMLDISNFRLHYFEYGCLDSLPHLRSLKLTA 1050
            ||.|:.....:.:..  |:|.. ||...|::|.::...|.        .||..::..:.::.|..
 Frog   492 LMPQSTRFTEKTVTV--PVTDA-NNGMPGIDEVMKTTKII--------IGCFVAITLMAAVMLVI 545

  Fly  1051 YSHL--EHFNIPHLLRHHYNIRQLWIEAPQPFTRIVKKGSGPTQEMQTLQLGNPTDLQREMEGHL 1113
            :..:  :|    |...||                      .||:.::.:.:.:.......:|.||
 Frog   546 FYKMRKQH----HRKNHH----------------------APTRTVEIINVDDELTADTPIESHL 584

  Fly  1114 PSKLTNITFSGPQFTNLNERILRGMRSPYLYMQLFNT 1150
            |       ....:..:||.  ....:||:.:....||
 Frog   585 P-------MPAIEHEHLNH--YNSYKSPFNHTTTVNT 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chp	NP_001263137.1	LRR	<84..320	CDD:443914
		leucine-rich repeat	84..103	CDD:275380
		leucine-rich repeat	104..128	CDD:275380
		leucine-rich repeat	129..152	CDD:275380
		leucine-rich repeat	153..177	CDD:275380
		leucine-rich repeat	178..201	CDD:275380
		leucine-rich repeat	202..226	CDD:275380
		leucine-rich repeat	227..250	CDD:275380
		leucine-rich repeat	251..279	CDD:275380
		leucine-rich repeat	280..326	CDD:275380
		leucine-rich repeat	327..348	CDD:275380
		leucine-rich repeat	352..375	CDD:275380
		PPP1R42	355..564	CDD:455733	30/110 (27%)
		leucine-rich repeat	376..401	CDD:275380
		leucine-rich repeat	426..450	CDD:275378
		leucine-rich repeat	451..474	CDD:275380	5/20 (25%)
		LRR_8	473..559	CDD:404697	24/85 (28%)
		leucine-rich repeat	475..524	CDD:275380	9/48 (19%)
		leucine-rich repeat	500..519	CDD:275380	0/18 (0%)
		leucine-rich repeat	525..548	CDD:275380	8/22 (36%)
		LRR	<540..>834	CDD:443914	72/317 (23%)
		leucine-rich repeat	549..574	CDD:275380	9/24 (38%)
		leucine-rich repeat	575..598	CDD:275380	8/22 (36%)
		leucine-rich repeat	599..622	CDD:275380	9/23 (39%)
		leucine-rich repeat	623..646	CDD:275380	9/22 (41%)
		leucine-rich repeat	647..730	CDD:275380	12/82 (15%)
		leucine-rich repeat	648..673	CDD:275380	2/24 (8%)
		leucine-rich repeat	674..705	CDD:275380	0/30 (0%)
		LRR	<730..1081	CDD:443914	63/403 (16%)
		leucine-rich repeat	731..754	CDD:275380	0/22 (0%)
		leucine-rich repeat	755..778	CDD:275380	6/22 (27%)
		leucine-rich repeat	779..802	CDD:275380	8/22 (36%)
		leucine-rich repeat	803..823	CDD:275380	5/19 (26%)
		leucine-rich repeat	852..876	CDD:275380	5/31 (16%)
		leucine-rich repeat	877..900	CDD:275380	4/22 (18%)
		leucine-rich repeat	901..925	CDD:275380	4/23 (17%)
		leucine-rich repeat	926..946	CDD:275380	2/19 (11%)
		leucine-rich repeat	947..970	CDD:275380	3/33 (9%)
		leucine-rich repeat	971..993	CDD:275380	5/21 (24%)
		leucine-rich repeat	994..1014	CDD:275380	4/19 (21%)
		leucine-rich repeat	1019..1042	CDD:275380	3/22 (14%)
lrrc4c	XP_002938986.1	LRRNT	47..78	CDD:214470	5/14 (36%)
		LRR	<76..322	CDD:443914	87/366 (24%)
		leucine-rich repeat	78..101	CDD:275380	9/55 (16%)
		leucine-rich repeat	102..125	CDD:275380	8/22 (36%)
		leucine-rich repeat	126..149	CDD:275380	9/24 (38%)
		leucine-rich repeat	150..173	CDD:275380	8/22 (36%)
		leucine-rich repeat	174..198	CDD:275380	9/23 (39%)
		leucine-rich repeat	199..220	CDD:275380	10/25 (40%)
		leucine-rich repeat	221..244	CDD:275380	11/103 (11%)
		leucine-rich repeat	245..268	CDD:275380	6/22 (27%)
		leucine-rich repeat	269..290	CDD:275380	7/20 (35%)
		LRRCT	301..351	CDD:214507	5/49 (10%)
		Ig	354..443	CDD:472250	19/117 (16%)
		Ig strand B	371..375	CDD:409353	1/3 (33%)
		Ig strand C	383..387	CDD:409353	1/3 (33%)
		Ig strand E	409..413	CDD:409353	1/12 (8%)
		Ig strand F	423..428	CDD:409353	1/4 (25%)
		Ig strand G	436..439	CDD:409353	0/2 (0%)