Protein Alignment dco and vrk1

DIOPT Version :10

• Sequence 1: NP_524602.1
• Gene: dco / 43673
• FlyBaseID: FBgn0002413
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: NP_998550.1
• Gene: vrk1 / 406694
• ZFINID: ZDB-GENE-040426-2709
• Length: 425
• Species: Danio rerio
• Alignment Length: 381
• Identity: 103/381 - (27%)
• Similarity: 171/381 - (44%)
• Gaps: 69/381 - (18%)

  Fly     8 KYRLGRKIGSGSFGDIYLGTTINTGEEVA-----IKLECIRTKHPQLHIESKFY----------- 56
            |::||..:|.|.||.:||....::|...|     ||:|  .:.:..|..|.|||
Zfish    37 KWKLGSAVGQGGFGLLYLANEDSSGPVTADAPYVIKVE--PSDNGPLFSELKFYMRAAKPDLIGA 99

  Fly    57 ----KTMQGGIGIPRIIWCG---SEGD-YNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMI 113
                |.|: .:|:|:....|   ..|. |..|||:..|..|:.||....::||.|.||.|..:::
Zfish   100 WMKSKKME-YLGVPKYWGSGFHEKNGKRYRFMVMDRFGTDLQKLFEGNGKKFSRKLVLQLGLRLL 163

  Fly   114 SRIDYIHSRDFIHRDIKPDNFLMGLGKKGNLVYIIDFGLAKKFRDARSLKHIP--YRENKNL--T 174
            ..::|||..:::|.|||..|.|:.. ...|.|:::|:|||.::    :.:.:|  |:|:...  .
Zfish   164 DILEYIHDHEYVHADIKASNLLLSY-TNPNQVFLVDYGLAYRY----APEGVPKEYKEDPKRCHD 223

  Fly   175 GTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGALPWQGLKAANKRQK--YERISEKKLSTSI 237
            ||..:.||:.|.|:..|||.|||.:||.::.:....|||:     :|.|.  |.|.|:.:...:|
Zfish   224 GTIEFTSIDAHKGVSPSRRADLEIMGYCMIQWLCSRLPWE-----DKLQDPLYVRDSKLRCRDNI 283

  Fly   238 VVLCK------GFPSEFVNYLNFCRQMHFDQRPDYCHLRKLFRNLFHRLGFTYDYVFDW------ 290
            ....|      ..|:|...::...:.:.:..||||..||.:.:.....:|.|.|...|:
Zfish   284 DEFLKSCFASGNIPAEMGKFMQEVKVLGYTDRPDYDKLRGILQQGLKSIGSTDDKKLDFGVATNS 348

  Fly   291 -NLLKFGGPRNPQAIQQAQDGADGQAGHDAVAAAAAVAAAAAASSHQQQQHKVNAA 345
             :|.....|:..:|.::.|             :|....:..|......|:.:||.|
Zfish   349 TSLPSVKTPKRKKAEEKGQ-------------SADETDSTPAKKRRAPQKKEVNGA 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_524602.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	89/309 (29%)
vrk1	NP_998550.1	Protein Kinases, catalytic domain	27..327	CDD:473864	89/302 (29%)
		PRK13808	<329..423	CDD:172341	14/76 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	343..425		10/62 (16%)