DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31371 and CG9698

DIOPT Version :9

Sequence 1:	NP_733375.2	Gene:	CG31371 / 43626	FlyBaseID:	FBgn0051371	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_651806.2	Gene:	CG9698 / 43629	FlyBaseID:	FBgn0039784	Length:	547	Species:	Drosophila melanogaster

Alignment Length:	547	Identity:	118/547 - (21%)
Similarity:	217/547 - (39%)	Gaps:	120/547 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VFSVLWLLQLFLLVESVAGANFARGEEQLQALLDTETQLIDGLRDYIERLERQLEEIRRETSAIE 68
            |||||:|| ....:.||:|..|.....::..:...|.:::..::.::...:.:|:.::   :.:.
  Fly     5 VFSVLFLL-FHQAIPSVSGVEFFSSIHEMTKVFGYEQKMVLHMQKFLSDNQDKLDFLK---ARLR 65

  Fly    69 EIHSQVDSVEE----YMGNPLNVFGILKRFESVWPGLEQ-KANATLEMVFGERLSDR------QL 122
            |..::.:...|    |..:|:|.:.:.||....|..:|. .|.:|     ||:...|      :.
  Fly    66 EFENERNEAREWGPSYFESPINKYLLNKRLTVDWQRVENLMATST-----GEKPLTRLRKFRNRE 125

  Fly   123 TLPSEEDYEESLNHLLHLQSVYELDSNSLSLGVVNGFKLGSSMSWGDCLEVAR---KSDFP-VAR 183
            |:|.:::.|.:::.||.||.||.|.:..|:.|:::|...|:.::...|:::||   :...| :|.
  Fly   126 TMPDKKELEGAIDGLLRLQYVYRLKAKDLARGILDGVDYGTQLNSEHCVDIARLALRDQHPRLAH 190

  Fly   184 FWLESALEKLPSASENSTESQRERESGRVHILEATLNIEYRAGELSRALATAEELLLLLPMNQGI 248
            .||..|.::|       |..::| |..:..||...:..:....:......|.:||:       ||
  Fly   191 SWLIEANDRL-------TGGEKE-EQLKPQILALLVQAKKELEDFRGLNDTYQELI-------GI 240

  Fly   249 QKAKRKIEK-------AMAKKEL------------------PKGRGQKSKAKKQISKSTEQLLIE 288
            |.|..:..|       |:::|.|                  |.|..|....
  Fly   241 QSASEEHAKNYETFLNALSEKALLNESKPILEHAPIPEEGEPVGEFQAYSL-------------- 291

  Fly   289 EICRGAKQQVTTGSRFNHC-QLDGSSPWLLLQPSRLEPVSSDPYIVLHHDVLTPKE--------S 344
             .|.|..:......|...| .:..:.|:|.:.|.:.|.:..||.:||:|||:...|        .
  Fly   292 -TCSGHWRLTPKEQRHLRCGYVTETHPFLWIAPLKAEELFQDPLLVLYHDVIYQSEIDVIRKLTE 355

  Fly   345 NELLQLIDEEEDTKGVSYQSLKLSKL------AQKKLGRISRLLGLEILELDPWTGRRH------ 397
            |.|::......:...||  :::.|:.      |.|.|..|.:.:. ::..|:......|
  Fly   356 NRLMRATITSHNESVVS--NVRTSQFTFIPVTAHKVLSTIDQRVA-DMTNLNMKYAEDHQFANYG 417

  Fly   398 --GH--EHI---------TKLEHSSEL-KHVARLMLNLQAPGMGGAVVFPQLELAVNVPRGSLLH 448
              ||  :|:         ..|..|.|: ..:|.::..|.....||...||||...:...:.:...
  Fly   418 IGGHYGQHMDWFYQTTFDAGLVSSPEMGNRIATVLFYLSDVAQGGGTAFPQLRTLLKPKKYAAAF 482

  Fly   449 WRTRFAGGSSSEWDYRSGQAICPVLLG 475
            |....|.|..   |.|:....||::.|
  Fly   483 WHNLHASGVG---DVRTQHGACPIIAG 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31371	NP_733375.2	P4Ha_N	30..156	CDD:285528	28/136 (21%)
CG9698	NP_651806.2	P4Ha_N	28..159	CDD:285528	28/138 (20%)
CG9698	NP_651806.2	P4Hc	345..516	CDD:214780	34/168 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461872
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391515at2759
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	7	6.850