DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31371 and PH4alphaMP

DIOPT Version :9

Sequence 1:	NP_733375.2	Gene:	CG31371 / 43626	FlyBaseID:	FBgn0051371	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_524594.2	Gene:	PH4alphaMP / 43624	FlyBaseID:	FBgn0026190	Length:	535	Species:	Drosophila melanogaster

Alignment Length:	557	Identity:	133/557 - (23%)
Similarity:	226/557 - (40%)	Gaps:	116/557 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LFLLVESVA-GANFARGEEQLQALLDTETQLIDGLRDYIERLERQLEEIRRETSAIEEIH-SQVD 75
            |||:::.:: ...|......|..|.:||..|:..|::|:..:.:..|.::.|..||...| :..|
  Fly     8 LFLVLQVLSCHGEFFSSTSGLAKLFETEVVLLAELQNYVNEINQHAEALQSEIDAIRVEHLNAAD 72

  Fly    76 SVEEYMGNPLNVFGILKRFESVWPGLEQKANA---------TLEMVFGERLSDRQLTLPSEEDYE 131
            .:::|:.||:|.|.::||..|.|...|....|         |:..:      ...|:.||::|:.
  Fly    73 GIDDYLNNPVNAFRLIKRLHSDWETFEGSVTADSSRSNYLDTMASL------KENLSFPSQDDFV 131

  Fly   132 ESLNHLLHLQSVYELDSNSLSLGVVNGFKLGSSMSWGDCLEVARK----SDFPVARFWLESALEK 192
            .|...|..||..|:||...|:.|::||.|.|::|||.||..:.:.    .|:.....||:.:::.
  Fly   132 GSAIALTRLQQTYQLDVAELASGILNGVKYGTAMSWQDCFVLGQHLYALRDYNHTVPWLQQSMQL 196

  Fly   193 LPSASENSTESQRERESGRVHILEATLNIEYRAGELSRALATAEELLLLLP-MNQGIQKAKRKIE 256
            |...|..|       ||..:..:||.:......|....||:....:|.:.| ....:.:|::::|
  Fly   197 LGEQSYGS-------ESASLDFMEAVVEYHREMGAHESALSLVNHVLSIEPDQRSHLLEARQQLE 254

  Fly   257 KAMAKKELPKGRGQK-------SKAKKQISKSTEQLLIEEICRGAKQQVTTGSRFNHCQLDGSSP 314
            :.:..       |.|       ::......:|.|..:.|::|||....:.:..|...|:|..|.
  Fly   255 ELITD-------GDKNGLLHLTARRPGDYHESREFRMYEQVCRGELAPLPSKQRNLRCRLRKSR- 311

  Fly   315 WLLLQPSRLEPVSSDPYIVLHHDVLTPKESNELLQLIDEE--------------------EDTKG 359
             |...|.:||.:..||.:|..|.|:..|:|:.|.:.....                    ..::|
  Fly   312 -LGYAPFKLEELHLDPLVVQLHQVIGSKDSDSLQKTARPRIKRSTVYSLGGNGGSTAAAFRTSQG 375

  Fly   360 VS--YQSLKLSKLAQKKLGRISRLLGLEILE------------LDP-W----------TGRRHGH 399
            .|  |.....:||..:.:|..|. |.::..|            .:| |          .|..||:
  Fly   376 ASFNYSRNAATKLLSRHVGDFSG-LNMDYAEDLQVANYGIGGHYEPHWDSFPENHIYQEGDLHGN 439

  Fly   400 EHITKLEHSSELKHVARLMLNLQAPGMGGAVVFPQLELAVNVPRGSLLHWRTRFAGGSSSEWDYR 464
            ...|.:.:.::::             .||...||.|.|.|...|||||.|......|   :.|:|
  Fly   440 RMATGIYYLADVE-------------AGGGTAFPFLPLLVTPERGSLLFWYNLHPSG---DQDFR 488

  Fly   465 SGQAICPVLLGVQLSVIACQSNVLRDTLYGPRGQDSI 501
            :..|.||||.|         |..:.:.....|.||::
  Fly   489 TKHAACPVLQG---------SKWIANVWIRERNQDNV 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31371	NP_733375.2	P4Ha_N	30..156	CDD:285528	38/135 (28%)
PH4alphaMP	NP_524594.2	P4Ha_N	24..156	CDD:285528	38/137 (28%)
PH4alphaMP	NP_524594.2	P4Hc	336..509	CDD:214780	41/198 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461830
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391515at2759
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	7	6.850