DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31371 and CG34041

DIOPT Version :9

Sequence 1:	NP_733375.2	Gene:	CG31371 / 43626	FlyBaseID:	FBgn0051371	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster

Alignment Length:	479	Identity:	104/479 - (21%)
Similarity:	181/479 - (37%)	Gaps:	93/479 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SVLW-------LLQLFLLVESVAGANFARGEEQLQALLDTETQLIDGLRDYIERLERQLEEIRRE 63
            ||:|       ||.:.:|.:..:..       :::|.||.:|:|...||.|.|.|:..:..:.|
  Fly     7 SVMWSALGFSPLLAVLILPKWASST-------KMKAYLDLDTRLKTQLRGYSEDLQDHISTLNR- 63

  Fly    64 TSAIEEIHSQVDSV----EEYMGNPLNVFGILKRFESVWPGLEQKANATLEMVFGERLSDRQLTL 124
              .|::..|::|.|    |.|:|||||.|.:|......||...:.....|...:...:.:....:
  Fly    64 --YIDDRKSELDKVGKDPEVYLGNPLNSFSLLHHLHFDWPAWRKLMEKPLATEYITEIQEMWSEM 126

  Fly   125 PSEEDYEESLN-----HLLHLQSVYE---LDSNSLSLG----------------VVNGFKLGSSM 165
            |::::|..|:.     |....|..:|   |:|..::|.                .:||:| ..|:
  Fly   127 PTKDEYTNSIKAAKDFHKNETQGNFEFSPLESLQIALHAYDKKNYTEAENWLNITLNGYK-NLSL 190

  Fly   166 SWGDCLEVARKSDFPVARFWLESALEKLPSASENSTESQRERE---SGRVHILEATLNIEY--RA 225
            ...|..||..    ||...:.|:....:.:.|.....|..:.|   .....||...|.|.|  .:
  Fly   191 QEKDLYEVLS----PVIMVYDETNGAAMIAKSYIRYFSNHQMEFIVMKSACILSVGLIIVYLSYS 251

  Fly   226 GELSRALATAEELLLLLPMNQGIQKAKRKIEKAMAKKELPKGRGQKSKAKKQISKSTEQLLIEEI 290
            ...:|...:..:::.:|.:.:.:.|.......|:..|...........|...|....::|.|
  Fly   252 NSENRHSLSKSKVINILKIQENVVKYLENYIYALETKLKTIDEALIDLATYHIQFERDKLAI--- 313

  Fly   291 CRGAKQQVTTGSRFNHCQLDGSSPWLLLQ--PSRLE---PVSSDPYIVLHHDVLTPKESNELLQL 350
               |...|.:.|..:|.|.|.:...|.||  |.:.|   .:|...|:...:|:      :|:...
  Fly   314 ---ASSPVASYSLIHHMQSDWTHWQLFLQEDPGKDELASLMSIKKYLPTKNDI------SEVCHG 369

  Fly   351 IDEEEDTKGVSYQSLKLSKLAQKKLGRISRLLGLEILELDPWTGRRHGHEHITKL-------EHS 408
            |.:..:...::.|.:....:...:...||..|.||.|.::....|     |:..|       :||
  Fly   370 ISKMLNAYLMTAQDIANGVILGTQTKYISSALKLEYLYMEIICNR-----HLMSLRDCVALSDHS 429

  Fly   409 SELK---------HVARLMLNLQA 423
            .|:|         :||..||...|
  Fly   430 MEMKDYNKSKEWLNVAISMLESSA 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31371	NP_733375.2	P4Ha_N	30..156	CDD:285528	36/153 (24%)
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528	30/118 (25%)
		P4Ha_N	260..389	CDD:285528	25/140 (18%)
		TPR repeat	452..491	CDD:276809	1/2 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461999
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840