DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31371 and CG31013

DIOPT Version :9

Sequence 1:	NP_733375.2	Gene:	CG31371 / 43626	FlyBaseID:	FBgn0051371	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_733394.3	Gene:	CG31013 / 326111	FlyBaseID:	FBgn0051013	Length:	534	Species:	Drosophila melanogaster

Alignment Length:	511	Identity:	123/511 - (24%)
Similarity:	194/511 - (37%)	Gaps:	115/511 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LLDTETQLIDGLRDYIERLERQLEEIRRETSAI--EEIHSQVDSVEEYMGNPLNVFGILKRFESV 97
            ||:.|.:|||.|.:|...||::||.||.:...|  |....:.::: .|:.||||.|.|::|....
  Fly    38 LLELEKKLIDNLENYTNALEQKLEIIRSQLLVIRAENEKGRRNAI-SYLSNPLNGFSIIRRLHQD 101

  Fly    98 WPG----LEQKANATLEMVFGERLSDRQLTLPSEEDYEESLNHLLHLQSVYELDSNSLSLGVVNG 158
            |..    :||.........|.....:    ||:|.|..::...:..:||.|:|.......|.:||
  Fly   102 WINWRKYMEQPVGIWQLKAFYSWKDE----LPTERDLWDACEGIARIQSTYDLKVGDFINGNING 162

  Fly   159 FKLGSSMSWGDCLEVA-------RKSDFPVARFWLESALEKLPSASENSTESQRERESGRVHILE 216
            .:...|||..|.|.|.       |.||   |..||:...::|   .|......|......|..|.
  Fly   163 KQYNDSMSTADILSVGAYLFMKNRPSD---AIQWLQEVPQRL---QEELLIQPRHLPIKEVDALR 221

  Fly   217 ATLNIEYRAGELSRALATAEELLLLLPMNQGIQKAKRK----IEK-------AMAKKELPKGRGQ 270
            .....:.:....|.||......|.|.|.:..:.:..:|    ||.       ...|:.:|.....
  Fly   222 LLAEAQIKDQNYSEALPLLHNCLKLQPHDARVLRLWKKTTDFIENQPDQSPTENKKRNVPIANAF 286

  Fly   271 KSKAKKQISKSTEQLLIEEICRGAKQQVTTGSRFNHCQLD-GSSPWLLLQPSRLEPVSSDPYIVL 334
            |......:..||..                     ||..: .::|:|.|.|.:.|.:..|||:||
  Fly   287 KLSCNGPLESSTRL---------------------HCFYNFTTTPFLRLAPLKTEQIGLDPYVVL 330

  Fly   335 HHDVLTPKESNELLQLIDEEEDTKGVSYQSLKLSKL------AQKKLGRISR--LLGLEILELDP 391
            :|:||:.:|.:.|:          |.:.|::|.:|:      .:|..||.::  .|..|..||..
  Fly   331 YHEVLSAREISMLI----------GKAAQNMKNTKIHKERAVPKKNRGRTAKGFWLKKESNELTK 385

  Fly   392 WTGRR----------------------HGHEHI--------------TKLEHSSEL-KHVARLML 419
            ...||                      .||..:              |:..:|.:| ..:|.::.
  Fly   386 RITRRIMDMTGFDLADSEGFQVINYGIGGHYFLHMDYFDFASSNHTDTRSRYSIDLGDRIATVLF 450

  Fly   420 NLQAPGMGGAVVFPQLELAVNVPRGSLLHWRTRFAGGSSSEWDYRSGQAICPVLLG 475
            .|.....|||.||..:...|:...|:.:.|......|:.   |.|:..|.|||::|
  Fly   451 YLTDVEQGGATVFGDVGYYVSPQAGTAIFWYNLDTDGNG---DPRTRHAACPVIVG 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31371	NP_733375.2	P4Ha_N	30..156	CDD:285528	37/126 (29%)
CG31013	NP_733394.3	P4Ha_N	31..160	CDD:285528	37/126 (29%)
		TPR_11	178..248	CDD:290150	16/75 (21%)
		TPR repeat	211..246	CDD:276809	6/34 (18%)
		P4Hc	336..513	CDD:214780	38/181 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461804
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391515at2759
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	7	6.850