Protein Alignment CG31371 and P4ha1

DIOPT Version :10

• Sequence 1: NP_733375.2
• Gene: CG31371 / 43626
• FlyBaseID: FBgn0051371
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_035160.1
• Gene: P4ha1 / 18451
• MGIID: 97463
• Length: 534
• Species: Mus musculus
• Alignment Length: 533
• Identity: 127/533 - (23%)
• Similarity: 228/533 - (42%)
• Gaps: 89/533 - (16%)

  Fly     7 VLW--LLQLFLLVESVAGANFARGEEQLQALLDTETQLIDGLRDYIERLERQLEEIRRETSAIEE 69
            ::|  |:...||.:|:|...|.....|:..|:..|..|:..|:|||:..|.:||:|::....::.
Mouse     1 MIWVVLMMAILLPQSLAHPGFFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDR 65

  Fly    70 IHS-QVDSVEEYMGNPLNVFGILKRFESVWPGLEQKANATLEMVFGERLSDRQLTLPSEEDYEES 133
            :.| .....|.::|:|:|.|.::||..:.|..||......:...|...|:.::...|::||...:
Mouse    66 LTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLILKDMSDGFISNLTIQRQYFPNDEDQVGA 130

  Fly   134 LNHLLHLQSVYELDSNSLSLGVVNGFKLGSSMSWGDCLEVAR----KSDFPVARFWLESALEKLP 194
            ...|..||..|.||:|::|.|.:.|.:..|.::..||.|:.:    ::|:.....|:|.||.:|.
Mouse   131 AKALFRLQDTYNLDTNTISKGNLPGVQHKSFLTAEDCFELGKVAYTEADYYHTELWMEQALTQLE 195

  Fly   195 SASENSTESQRERESGRVHILEATLNIEYRAGELSRALATAEELLLLLPMNQGIQKAKRKIEKAM 259
            ....::.:        :|.:|:......|:.|:|.:||...::||.|.|.:|.........|..|
Mouse   196 EGELSTVD--------KVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLVYFEYIM 252

  Fly   260 AK-KELPKGRG-----QKSKAKKQ---ISKSTEQLLIEEICRG------AKQQVTTGSRFNHCQL 309
            :| |:..|...     ||:..||:   :....|:...|.:|||      .::|.....|::
Mouse   253 SKEKDANKSASGDQSDQKTAPKKKGIAVDYLPERQKYEMLCRGEGIKMTPRRQKRLFCRYH---- 313

  Fly   310 DGS-SPWLLLQPSRLEPVSSDPYIVLHHDVLTPKESNELLQLIDEEEDTKGVSYQSLKLSKLAQK 373
            ||: :|..:|.|::.|.....|.|:..||:::..|.          |..|.::...|:.:.::..
Mouse   314 DGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEI----------EIVKDLAKPRLRRATISNP 368

  Fly   374 KLG----------------------------RISRLLGLEILELDPWTGRRHG-------HEHIT 403
            ..|                            ||..|.||::...:......:|       |....
Mouse   369 VTGALETVHYRISKSAWLSGYEDPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFA 433

  Fly   404 KLEHSSELK------HVARLMLNLQAPGMGGAVVFPQLELAVNVPRGSLLHWRTRFAGGSSSEWD 462
            :.:.....:      .:|..:..:.....|||.|||::..:|...:|:.:.|...||.|   |.|
Mouse   434 RKDEPDAFRELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASG---EGD 495

  Fly   463 YRSGQAICPVLLG 475
            |.:..|.||||:|
Mouse   496 YSTRHAACPVLVG 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31371	NP_733375.2	P4Ha_N	30..158	CDD:462433	37/128 (29%)
P4ha1	NP_035160.1	P4Ha_N	24..155	CDD:462433	37/130 (28%)
		TPR	205..238		11/32 (34%)
		P4Hc	345..518	CDD:214780	34/177 (19%)