DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CDase and AT5G58980

DIOPT Version :9

Sequence 1:	NP_001263109.1	Gene:	CDase / 43618	FlyBaseID:	FBgn0039774	Length:	704	Species:	Drosophila melanogaster
Sequence 2:	NP_200706.1	Gene:	AT5G58980 / 836015	AraportID:	AT5G58980	Length:	733	Species:	Arabidopsis thaliana

Alignment Length:	732	Identity:	287/732 - (39%)
Similarity:	407/732 - (55%)	Gaps:	50/732 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FLAFLAVSFLCGLVSATYKVGVGRADITGPPVEINFMGYANIKQVGRGIHTRVFARAFVVEDEKG 72
            ||.|| :...|....:.|.:|:|..|||||..::|.|||||::||..|:|.|:.||||:|.:...
plant    13 FLLFL-LRLTCIFSDSDYLMGLGSYDITGPAADVNMMGYANMEQVASGVHFRLRARAFIVAEPYK 76

  Fly    73 NRVAFVSADAGMMGYGLKREVIKRLQARYGNIYHNDNVAISGTHTHGAPGGFLMHLLYDISILGF 137
            .|:|||:.||||....:..:||:||:.|||.:|..:||||||||||..|||:|.::||.::.|||
plant    77 KRIAFVNLDAGMASQLVTIKVIERLKQRYGELYTEENVAISGTHTHAGPGGYLQYILYLVTSLGF 141

  Fly   138 VPQTFEVMAQGLYLCIKRATDNLVDGRILLSKTTVLNVNINRSPSSYLRNPAEERAQYEHDTDKT 202
            |.|:|..:..|:...|.:|.:||..|.||::|..:|:..:|||||:||.|||.||::||:|.||.
plant   142 VHQSFNALVDGIEQSIIQAHENLRPGSILINKGELLDAGVNRSPSAYLNNPAHERSKYEYDVDKE 206

  Fly   203 LTQLRFVDLENNLLGAF--NWYAVHATSMNNTNRLVTSDNVGYAALLLEKEYNPNKM-------- 257
            :|.::|||.:...:...  :|:     ...|..|.|..::....:.::...|:.:.|
plant   207 MTLVKFVDDQWGPVARIMEDWF-----ERENGCRSVDVESPRRVSSIISDPYDQDLMEMASSLLS 266

  Fly   258 ----------------------PGKGKFVGAFCSSNLGDVSPNIMGPKCSISGNECDLLTSRCPT 300
                                  ..|.:||.|||.:|.||||||::|..|..:|..|:...|.|..
plant   267 TGGKTVTRMSSVARRVRSRFRHADKPRFVSAFCQTNCGDVSPNVLGAFCIDTGLPCEFNQSTCGG 331

  Fly   301 GEGDCFASGPG-KDMFESTQILGQRLADAALGLLNEQSQESTAREVTGDVRFIHQFVDMPNYNGS 364
            ....|:..||| .|.||||:|:|:|....|..|..:.|:     |:.|.|.:.|.:||..... .
plant   332 KNEQCYGRGPGYPDEFESTRIIGERQFKKAADLFTKASE-----EIQGKVDYRHAYVDFSQLE-V 390

  Fly   365 TYNPLSRKVDKIRGCQPAMGYSFAAGTTDGPGAFSFEQGTTTDNPMWNFVRDFIAAPTQEDIKCH 429
            |.|..:...:.::.|..|||:.||||||||||||.|:||....||.|..||:.:..||:|.::|.
plant   391 TINGQNGGSEVVKTCPAAMGFGFAAGTTDGPGAFDFKQGDDQGNPFWRLVRNLLKNPTEEQVRCQ 455

  Fly   430 EPKPILLATGRATFPYEWQPKIVSDQLLKIGDVIIAAVPCEFTTMAGRRLRNQIRAA-ASAVGGI 493
            .||||||.||....||:|.|.|:..|:|:||.::|..||.|||||||||||:.::.. .....|.
plant   456 RPKPILLDTGEMKQPYDWAPSILPVQILRIGQLVILCVPGEFTTMAGRRLRDAVKTVLKEGSNGR 520

  Fly   494 DTEVIIAGLTNIYTSYTVTPEEYQAQRYEAASTIFGPHTHSIYMDVFERLTKAMMRNETVDAGPS 558
            :..|:||||||.|:.|..|.||||.||||.|||::||||.|.|:..|::|...::..:|.|.||.
plant   521 EFSVVIAGLTNSYSQYIATFEEYQVQRYEGASTLYGPHTLSGYIQEFKKLANDLLSAQTTDPGPQ 585

  Fly   559 PPYMNDVMLSLNTGVLFDGHPINTDFGYVKS---QPNKEYGINETVKVTYISGNPRNNLFTEKTY 620
            ||.:....:||.|.|:.|..||.|.||.|.|   :.:|.....:.|:|.:.|.||||:|.||.|:
plant   586 PPDLLHKQISLLTPVVADMTPIGTAFGDVTSDVPRLSKFRKGADIVRVQFRSANPRNDLMTEGTF 650

  Fly   621 FTIERKI-NEDRWKVAYTDASWETKMVWHRTNTILGFSEMDIYWDISPQTLPGEYRIRHSGEYKY 684
            ..:||.: ..:.|...|.|..:..:..|.|...:...|...|.|.|.....||.|||.|.|..|.
plant   651 ALVERWLEGRETWVPVYDDDDFCLRFKWSRPFKLSTQSTATIEWRIPETASPGVYRITHFGSAKT 715

  Fly   685 ILGGKYPYEGLTHSFTV 701
            .:...:.:.|.:.:|.|
plant   716 PISSIHHFSGSSSAFVV 732

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CDase	NP_001263109.1	PTZ00487	24..701	CDD:240437	281/714 (39%)
		Ceramidase_alk	25..538	CDD:282576	228/546 (42%)
		Ceramidse_alk_C	540..701	CDD:293653	53/164 (32%)
AT5G58980	NP_200706.1	Ceramidase_alk	29..565	CDD:309742	228/546 (42%)
AT5G58980	NP_200706.1	Ceramidse_alk_C	567..732	CDD:319107	53/164 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	423	1.000	Domainoid score	I118
eggNOG	1	0.900	-	-		E1_KOG2232
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	514	1.000	Inparanoid score	I298
OMA	1	1.010	-	-		QHG63482
OrthoDB	1	1.010	-	-		D967085at2759
OrthoFinder	1	1.000	-	-		FOG0003346
OrthoInspector	1	1.000	-	-		otm3163
orthoMCL	1	0.900	-	-		OOG6_103367
Panther	1	1.100	-	-	O	PTHR12670
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3230
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840