| Sequence 1: | NP_001263109.1 | Gene: | CDase / 43618 | FlyBaseID: | FBgn0039774 | Length: | 704 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_063946.2 | Gene: | ASAH2 / 56624 | HGNCID: | 18860 | Length: | 780 | Species: | Homo sapiens |
| Alignment Length: | 697 | Identity: | 307/697 - (44%) |
|---|---|---|---|
| Similarity: | 425/697 - (60%) | Gaps: | 41/697 - (5%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 25 YKVGVGRADITGPPVEINFMGYANIKQVGRGIHTRVFARAFVVEDEKG-NRVAFVSADAGMMGYG 88
Fly 89 LKREVIKRLQARYGNIYHNDNVAISGTHTHGAPGGFLMHLLYDISILGFVPQTFEVMAQGLYLCI 153
Fly 154 KRATDNLVDGRILLSKTTVLNVNINRSPSSYLRNPAEERAQYEHDTDKTLTQLRFVDLENNLLGA 218
Fly 219 FNWYAVHATSMNNTNRLVTSDNVGYAALLLEKEYNPNKMPGKGKFVGAFCSSNLGDVSPNIMGPK 283
Fly 284 CSISGNECDLLTSRCPT-GEGDCFASGPGKDMFESTQILGQRLADAALGLLNEQSQESTAREVTG 347
Fly 348 DVRFIHQFVDMPN---YNGSTYNPLSRKVDKIRGCQPAMGYSFAAGTTDGPGAFSFEQGTTTDNP 409
Fly 410 MWNFVRDFIAAPTQEDIK-CHEPKPILLATGRATFPYEWQPKIVSDQLLKIGDVIIAAVPCEFTT 473
Fly 474 MAGRRLRNQIRAAASAVGGIDTEVIIAGLTNIYTSYTVTPEEYQAQRYEAASTIFGPHTHSIYMD 538
Fly 539 VFERLTKAMMRNETV---DAGPSPPYMNDVMLSLNTGVLFDGHPINTDFGYVKSQPNKEYGINET 600
Fly 601 VKVTYISGNPRNNL--FTEKTYFTIER-KINEDRWKVAYTDASWETKMVWHRTNTILGFSEMDIY 662
Fly 663 WDISPQTLPGEYRIRHSGEYK--------YILGGKYPYEGLTHSFTV 701 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CDase | NP_001263109.1 | PTZ00487 | 24..701 | CDD:240437 | 306/695 (44%) |
| Ceramidase_alk | 25..538 | CDD:282576 | 253/518 (49%) | ||
| Ceramidse_alk_C | 540..701 | CDD:293653 | 53/174 (30%) | ||
| ASAH2 | NP_063946.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 47..90 | ||
| PTZ00487 | 100..778 | CDD:240437 | 307/697 (44%) | ||
| Ceramidase_alk | 102..608 | CDD:282576 | 253/518 (49%) | ||
| Ceramidse_alk_C | 610..777 | CDD:293653 | 53/174 (30%) | ||
| Required for correct folding and localization. /evidence=ECO:0000250|UniProtKB:Q91XT9 | 770..780 | 3/8 (38%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165141660 | |
| Domainoid | 1 | 1.000 | 489 | 1.000 | Domainoid score | I382 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H10310 | |
| Inparanoid | 1 | 1.050 | 570 | 1.000 | Inparanoid score | I1059 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S6313 |
| OMA | 1 | 1.010 | - | - | QHG63482 | |
| OrthoDB | 1 | 1.010 | - | - | D118111at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0003346 | |
| OrthoInspector | 1 | 1.000 | - | - | oto91035 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_103367 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR12670 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X3230 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 14 | 13.860 | |||||