Protein Alignment: CDase and asah2

• Sequence 1: NP_001263109.1
• Gene: CDase
• FlyBaseID: FBgn0039774
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_001007764.1
• Gene: asah2
• ZFINID: ZDB-GENE-041112-1
• Length: 743
• Species: Danio rerio
• Alignment Length: 695
• Identity: 302/696 (43%)
• Similarity: 419/696 (60%)
• Gaps: 37/696 (5%)

  Fly    25 YKVGVGRADITGPPVEINFMGYANIKQVGRGIHTRVFARAFVVEDEKGN-RVAFVSADAGMMGYG 88
            |.:||||||.|||..::..|||||..|..||:|||:|:|||:|:|  || ||.||::|.||:...
Zfish    61 YLIGVGRADCTGPVADLPMMGYANTDQTARGLHTRLFSRAFIVDD--GNKRVVFVTSDIGMVSQR 123

  Fly    89 LKREVIKRLQARYGNIYHNDNVAISGTHTHGAPGGFLMHLLYDISILGFVPQTFEVMAQGLYLCI 153
            |:.||.:.|:.:||::|..|||.:||||||...||:..:.|:.|:..|::..:.:.:..|:...|
Zfish   124 LRLEVFQALKEKYGDLYRQDNVVLSGTHTHSGVGGYFQYTLFMITSKGYIKPSIQAIVSGIVKSI 188

  Fly   154 KRATDNLVDGRILLSKTTVLNVNINRSPSSYLRNPAEERAQYEHDTDKTLTQLRFVDLENNLLGA 218
            ..|..||..|||.::|..|.:.|.||||.||:.||.|||.:||.:|||.:..|:|.||:.:.:|.
Zfish   189 DIAHRNLRPGRIFINKGQVADSNFNRSPHSYMNNPEEERNRYEFNTDKQIVVLKFTDLDGDGIGL 253

  Fly   219 FNWYAVHATSMNNTNRLVTSDNVGYAALLLEKEYNPNKMPG-KGKFVGAFCSSNLGDVSPNIMGP 282
            .:|:|||..|||.|||:|:|||:|||:.:.|:|.|...:|| ||.||..|.||||||.||||.||
Zfish   254 LSWFAVHPVSMNYTNRMVSSDNLGYASYIFEQEKNIGFLPGEKGPFVAGFSSSNLGDSSPNIRGP 318

  Fly   283 KCSISGNECDLLTSRCPT-GEGDCFASGPGKDMFESTQILGQRLADAALGLLNEQSQESTAREVT 346
            .|..:|.:||.:.|.||. |:..|.|.|||:||||||:|:|:.:...|..|..     |..:|:.
Zfish   319 VCVNTGLKCDYINSSCPVGGKKACIAFGPGEDMFESTRIIGENMFKIAKELYG-----SAKQELH 378

  Fly   347 GDVRFIHQFVDMPN----YNGSTYNPLSRKVDKIRGCQPAMGYSFAAGTTDGPGAFSFEQGTTTD 407
            |.|...||:|:|.:    :| ||:..        |.|:||:|:|||||||||.|.|:|.||.|..
Zfish   379 GPVYGAHQWVNMTDETVQFN-STHTG--------RTCKPALGHSFAAGTTDGGGEFNFLQGDTEG 434

  Fly   408 NPMWNFVRDFIAAPTQEDIK-CHEPKPILLATGRATFPYEWQPKIVSDQLLKIGDVIIAAVPCEF 471
            :|.|:.:||.:..|...:.| ||:|||||.:||....|..|.|.||..|::.||.:.:.|||.||
Zfish   435 DPFWDGIRDAVLGPPSNETKACHQPKPILFSTGEMDSPLPWHPAIVDVQIITIGSLAVVAVPGEF 499

  Fly   472 TTMAGRRLRNQIRAAASAVGGI-DTEVIIAGLTNIYTSYTVTPEEYQAQRYEAASTIFGPHTHSI 535
            |||:|||:|..::......... :.||::|||.||||.|..|.||||.||||.|||||||||.|.
Zfish   500 TTMSGRRIREAVKRELEVKEPFTNAEVVVAGLCNIYTHYITTYEEYQIQRYEGASTIFGPHTLSA 564

  Fly   536 YMDVFERLTKAMMRNE--TVDAGPSPPYMN-DVMLSLNTGVLFDGHPINTDFGYVKSQPNKEYGI 597
            |:..:..|.||:....  .:..||.||:.: |.:.:.....:.|..|:.|.||.|..:.|..|.:
Zfish   565 YIQRYRGLAKAIAHGTIGELPKGPEPPFFDEDKLFNQVRDPVADVAPVGTTFGDVLQEVNPVYKV 629

  Fly   598 NETVKVTYISGNPRNN-LFTEKTYFTIERKINE-DRWKVAYTDASWETKMVWHRTNTILGFSEMD 660
            .|...||::|||||:: ...:.|..|:||..|: ..|::.:.||||||:..|  ...:.|.|:..
Zfish   630 GEIASVTFVSGNPRHSGDIRDTTLVTVERFHNDTGSWEIIHNDASWETRFHW--IKGLAGRSQAK 692

  Fly   661 IYWDISPQTL-PGEYRIRHSGEYKYILGGK---YPYEGLTHSFTV 701
            :.|.| |||. .|.|:|::.|.||......   .||.|.:.:|.|
Zfish   693 VEWHI-PQTAQAGTYQIQYFGHYKQTTENTTVITPYVGTSAAFKV 736

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDase	NP_001263109.1	PTZ00487	24..701	CDD:240437	301/694 (43%)
		Ceramidase_alk	25..538	CDD:282576	247/522 (47%)
		Ceramidse_alk_C	540..701	CDD:293653	54/170 (32%)
asah2	NP_001007764.1	PTZ00487	61..736	CDD:240437	301/694 (43%)
		Ceramidase_alk	61..567	CDD:282576	247/522 (47%)
		Ceramidse_alk_C	569..736	CDD:293653	54/170 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C256960281
eggNOG	1	0.900				E1_KOG2232
Hieranoid	1	1.000
Homologene	1	1.000				H10310
Inparanoid	1	1.050	543	1.000	Inparanoid score	I1118
OMA	1	1.010
OrthoDB	1	1.010				D118111at33208
OrthoFinder	1	1.000				FOG0006479
OrthoInspector	1	1.000				T1053002
orthoMCL	1	0.900				OOG5_129670
Panther	1	1.100			LDO	PTHR12670
Phylome	1	0.910		0.800	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R4679
TreeFam	1	0.960
ZFIN	0	0.000	Not matched by this tool.
	14	13.800