Protein Alignment CDase and LOC100494440

DIOPT Version :10

• Sequence 1: NP_651797.1
• Gene: CDase / 43618
• FlyBaseID: FBgn0039774
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: XP_031762500.1
• Gene: LOC100494440 / 100494440
• XenbaseID: XB-GENE-29082183
• Length: 761
• Species: Xenopus tropicalis
• Alignment Length: 688
• Identity: 297/688 - (43%)
• Similarity: 406/688 - (59%)
• Gaps: 41/688 - (5%)

  Fly    25 YKVGVGRADITGPPVEINFMGYANIKQVGRGIHTRVFARAFVV-EDEKGNRVAFVSADAGMMGYG 88
            |::||||.|.||...|:..||||...|:..|:|.|.::|||:: |.:...||.:||.:.|||...
 Frog    89 YRIGVGRTDCTGLLAEVPLMGYAKSDQIASGLHLRQYSRAFIIAEPDDSKRVVYVSTNIGMMSQR 153

  Fly    89 LKREVIKRLQARYGNIYHNDNVAISGTHTHGAPGGFLMHLLYDISILGF-VPQTFEVMAQGLYLC 152
            ::.||::.|:..|||:|..|||.:|.::||..|.|:..:..:.::..|| .||| .|:..|:...
 Frog   154 VRLEVMEELKVNYGNLYREDNVILSASNTHSGPAGYFQYNTFVLASQGFNRPQT-NVIVSGIVKS 217

  Fly   153 IKRATDNLVDGRILLSKTTVLNVNINRSPSSYLRNPAEERAQYEHDTDKTLTQLRFVDLENNLLG 217
            |:||..|:..|:|.::|.||.|..|||||||||.||..||.:|..:|||.:..|:.||:.:..:|
 Frog   218 IERAHQNMKRGKIFMNKGTVENSQINRSPSSYLLNPESERIRYSSNTDKDMVILKMVDMNDQDMG 282

  Fly   218 AFNWYAVHATSMNNTNRLVTSDNVGYAALLLEKEYNPNKMPGKGKFVGAFCSSNLGDVSPNIMGP 282
            ..:|:|||..||.|.|:|::|||:|||:.|.|:|.|...:||.|.||.||..|||||||||.|||
 Frog   283 MISWFAVHGVSMGNANKLISSDNLGYASYLFEQEKNNRSLPGTGSFVAAFSPSNLGDVSPNTMGP 347

  Fly   283 KCSISGNECDLLTSRCPTGEG-DCFASGPGKDMFESTQILGQRLADAALGLLNEQSQESTAREVT 346
            .|..:...||..||.||.|.. .|.|.||||||||||:|:|:|:...|..|....|     ||:.
 Frog   348 HCVNANETCDNPTSTCPAGGSVACVALGPGKDMFESTKIIGERIFLKAKELYGNAS-----RELD 407

  Fly   347 GDVRFIHQFVDMPNYNGSTYNPLSRKVDKIRGCQPAMGYSFAAGTTDGPGAFSFEQGTTTDNPMW 411
            ..|.|.||:|||.|.....     .:...::.|:||:|||||||||||.|:.:|.|||...:..|
 Frog   408 KKVNFAHQWVDMSNVTVKL-----NETHSVKTCKPALGYSFAAGTTDGAGSINFTQGTLEGDLYW 467

  Fly   412 NFVRD-FIAAPTQEDIKCHEPKPILLATGRATFPYEWQPKIVSDQLLKIGDVIIAAVPCEFTTMA 475
            |.:|| ::.||::|..:||.|||||:.||:...|..|.||||..|:..||.:.:.|:|.||||||
 Frog   468 NAIRDLYLGAPSKETQECHHPKPILINTGQMDKPIPWHPKIVDIQMFTIGSIALLALPGEFTTMA 532

  Fly   476 GRRLRNQIRAAASAVGGIDTEVIIAGLTNIYTSYTVTPEEYQAQRYEAASTIFGPHTHSIYMDVF 540
            ||||:.:::......|.::|:|:::||.|:||.|..|.||||||||||||||:||||.|.|:.:|
 Frog   533 GRRLQEEVKKILDPSGTLNTDVVLSGLCNVYTHYITTYEEYQAQRYEAASTIYGPHTLSAYLQLF 597

  Fly   541 ERLTKAMMRNET--VDAGPSPPYMNDVML--SLNTGVLFDGHPINTDFGYVKSQPNKEYGINETV 601
            ..|.||::.|.|  :..||.||.:|:.:|  || ..|..|..|.|.|||.|.......|...:.|
 Frog   598 NGLAKAIVENTTDELPKGPRPPLINESLLPNSL-PPVPPDSTPANKDFGDVLKDVYPRYRRGDIV 661

  Fly   602 KVTYISGNPRN--NLFTEKTYFTIERKINEDRWKVAYTDASWETKMVWHR--TNTILGFSEMDIY 662
            ..|:::.|||:  |..:|.:|..: ||.|..  .:.|.||||||:..||:  .|.    |.....
 Frog   662 SCTFVAANPRSGVNRMSESSYVYV-RKHNSR--VMLYNDASWETRYYWHKGPGNQ----SNATAE 719

  Fly   663 WDISPQTLPGEYRIRHSGEYK----------YILGGKY 690
            |.|.....||.|.|...|.|:          ||.|..:
 Frog   720 WHIPLSAEPGLYYIEVCGYYQPRSSFPVPQVYIGGSSF 757

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDase	NP_651797.1	Ceramidase_alk	25..538	CDD:461415	241/516 (47%)
		Ceramidse_alk_C	540..701	CDD:465340	56/169 (33%)
LOC100494440	XP_031762500.1	Ceramidase_alk	89..595	CDD:461415	241/516 (47%)
		Ceramidse_alk_C	597..760	CDD:465340	56/169 (33%)