Protein Alignment CG2224 and Stambpl1

DIOPT Version :10

• Sequence 1: NP_651796.1
• Gene: CG2224 / 43617
• FlyBaseID: FBgn0039773
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_083958.3
• Gene: Stambpl1 / 76630
• MGIID: 1923880
• Length: 436
• Species: Mus musculus
• Alignment Length: 431
• Identity: 178/431 - (41%)
• Similarity: 252/431 - (58%)
• Gaps: 42/431 - (9%)

  Fly    13 VEPQERMKHLSHCGNLIEVDKNMPVTRYYRSGTEMLRMANVYLREGNHENAFILYLRYMTLFIEK 77
            :.|:||::.||..|..|.:::::...||:|||.||.|||:|||.|||.||||:||.:::|||:||
Mouse    24 LSPEERVRALSKLGCNISINEDITPRRYFRSGVEMERMASVYLEEGNLENAFVLYNKFITLFVEK 88

  Fly    78 IRQHPDYGSVKA-EVRDINRKIKDEIMPTTEKLRAKLLTHYQREYEQFLASK---EAERVKELER 138
            :..|.||..... |.:||.:|:|:...|.|::|:..||..|..||:::|.||   :||.:|:||.
Mouse    89 LPSHRDYQQCAVPEKQDIMKKLKEIAFPRTDELKTDLLRKYNIEYQEYLQSKNKYKAEILKKLEH 153

  Fly   139 ERERERERQR-------QKERE---------KAGSSAIPSLIPANLHVLID--EGNQPSAPDLGL 185
            :|..|.||||       |.|.|         |....|...:...:..||.:  :|:..|.
Mouse   154 QRLIEAERQRIAQMRQQQLESEQFLFFEDQLKKQELARGQIRGQDSPVLSEQTDGSALSC----- 213

  Fly   186 LDQVVYPNDFPTGANRSLPGSGLLLPAASEAAADKTTNSKPSFDRNQKP--SYNRTDSLLAGSLR 248
                     |.|..:.||..:....|..|:.:  ...|..|..:|..||  :.:...:|:...||
Mouse   214 ---------FSTHQSNSLRNAFADHPHKSDGS--NFANYSPPVNRALKPAATLSAVQNLVVEGLR 267

  Fly   249 LVYVPGDTMEVFLKLALANTSKNIETCGVLAGHLSQNQLYITHIITPQQQGTPDSCNTMHEEQIF 313
            .|.:..|....||.||.:||.:.|||||:|.|.|:.|:..|||::.|:|...||.|:..:.|::|
Mouse   268 CVVLSRDLCHKFLLLADSNTVRGIETCGILCGKLTHNEFTITHVVVPKQSAGPDYCDVENVEELF 332

  Fly   314 DVQDQMQLITLGWIHTHPTQTAFLSSVDLHTHCSYQIMMPEALAIVCAPKYNTTGFFILTPHYGL 378
            :||||..|:|||||||||||||||||||||||||||:|:|||:||||:||:..||.|.|| :.|:
Mouse   333 NVQDQHGLLTLGWIHTHPTQTAFLSSVDLHTHCSYQLMLPEAIAIVCSPKHKDTGIFRLT-NAGM 396

  Fly   379 DYIAQCRQSGFHPHPNDPPLFMEAQHIRMDNQAKIKVIDLR 419
            ..::.|::.|||||..||.||....|: :....|..|:|||
Mouse   397 LEVSTCKKKGFHPHTKDPKLFSICSHV-LVKDIKTTVLDLR 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2224	NP_651796.1	USP8_dimer	11..120	CDD:462647	48/107 (45%)
		MPN_AMSH_like	247..419	CDD:163697	91/171 (53%)
Stambpl1	NP_083958.3	USP8_dimer	28..132	CDD:462647	47/103 (46%)
		HlpA	<101..>176	CDD:442073	29/74 (39%)
		MPN_AMSH_like	266..436	CDD:163697	91/171 (53%)
		JAMM motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01182	347..360		12/12 (100%)