Protein Alignment CG2224 and Stambpl1

DIOPT Version :10

• Sequence 1: NP_651796.1
• Gene: CG2224 / 43617
• FlyBaseID: FBgn0039773
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_001108520.1
• Gene: Stambpl1 / 687696
• RGDID: 1583011
• Length: 436
• Species: Rattus norvegicus
• Alignment Length: 421
• Identity: 177/421 - (42%)
• Similarity: 247/421 - (58%)
• Gaps: 22/421 - (5%)

  Fly    13 VEPQERMKHLSHCGNLIEVDKNMPVTRYYRSGTEMLRMANVYLREGNHENAFILYLRYMTLFIEK 77
            :.|:||::.||..|..|.:::::...||:|||.||.|||:|||.|||.||||:||.:::|||:||
  Rat    24 LSPEERVRALSKLGCNISINEDITPRRYFRSGVEMERMASVYLEEGNLENAFVLYNKFITLFVEK 88

  Fly    78 IRQHPDYGSVKA-EVRDINRKIKDEIMPTTEKLRAKLLTHYQREYEQFLASK---EAERVKELER 138
            :..|.||..... |.:||.:|:|:...|.|::|:..||..|..||:::|.||   :||.:|:||.
  Rat    89 LPSHRDYQQCAVPEKQDIMKKLKEIAFPRTDELKTDLLRKYNIEYQEYLQSKNKYKAEILKKLEH 153

  Fly   139 ERERERERQR--QKEREKAGSSAIPSLIPANLHVLIDEGNQPSAPDLGLLDQVVYPND------F 195
            :|..|.||||  |..:::..|..............:..|.......|.|.:|    .|      |
  Rat   154 QRLIEAERQRIAQMRQQQLESEQFLFFEDQLKKQELARGQTRGQDSLVLSEQ----TDGSGLSCF 214

  Fly   196 PTGANRSLPGSGLLLPAASEAAADKTTNSKPSFDRNQKP--SYNRTDSLLAGSLRLVYVPGDTME 258
            .|..|.||.......|..|:..  ...|..|..:|..||  :.:...:|:...||.|.:..|...
  Rat   215 STHQNNSLRNVFADHPQKSDVC--DLANYSPPVNRALKPAATLSAVQNLVVEGLRCVVLSRDLCH 277

  Fly   259 VFLKLALANTSKNIETCGVLAGHLSQNQLYITHIITPQQQGTPDSCNTMHEEQIFDVQDQMQLIT 323
            .||.||.:||.:.|||||:|.|.|:.|:..|||::.|:|...||.|:..:.|::|.||||..|:|
  Rat   278 KFLLLADSNTVRGIETCGILCGKLTHNEFTITHVVVPKQSAGPDYCDVENVEELFSVQDQHGLLT 342

  Fly   324 LGWIHTHPTQTAFLSSVDLHTHCSYQIMMPEALAIVCAPKYNTTGFFILTPHYGLDYIAQCRQSG 388
            ||||||||||||||||||||||||||:|:|||:||||:||:..||.|.|| :.|:..::.|::.|
  Rat   343 LGWIHTHPTQTAFLSSVDLHTHCSYQLMLPEAIAIVCSPKHKDTGIFRLT-NAGMLEVSTCKKKG 406

  Fly   389 FHPHPNDPPLFMEAQHIRMDNQAKIKVIDLR 419
            ||||..||.||....|: :....|..|:|||
  Rat   407 FHPHTKDPKLFSICSHV-LVKDIKTTVLDLR 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2224	NP_651796.1	USP8_dimer	11..120	CDD:462647	48/107 (45%)
		MPN_AMSH_like	247..419	CDD:163697	91/171 (53%)
Stambpl1	NP_001108520.1	USP8_dimer	28..132	CDD:462647	47/103 (46%)
		HlpA	<101..>176	CDD:442073	29/74 (39%)
		MPN_AMSH_like	266..436	CDD:163697	91/171 (53%)