Protein Alignment: CG2224 and Stambp

• Sequence 1: NP_001263108.1
• Gene: CG2224
• FlyBaseID: FBgn0039773
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_612540.1
• Gene: Stambp
• RGDID: 619963
• Length: 424
• Species: Rattus norvegicus
• Alignment Length: 434
• Identity: 188/435 (43%)
• Similarity: 266/435 (61%)
• Gaps: 49/435 (11%)

  Fly    15 PQERMKHLSHCGNLIEVDKNMPVTRYYRSGTEMLRMANVYLREGNHENAFILYLRYMTLFIEKIR 79
            ||:|::.||..|:.:|:::::|..||:|||.|::|||::|..|||.|:|||||.:|:||||||:.
  Rat    11 PQDRVRILSQLGSAVELNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAFILYNKYITLFIEKLP 75

  Fly    80 QHPDYGS-VKAEVRDINRKIKDEIMPTTEKLRAKLLTHYQREYEQFLASKEAERVKELER----- 138
            :|.||.| :..|.:|..:|:|:...|..|:|:.:||..|.:||||:...|:.|. :||.|
  Rat    76 KHRDYKSAIIPEKKDAVKKLKNVAFPKAEELKTELLKRYTKEYEQYKERKKKEE-EELARNIAIQ 139

  Fly   139 -ERERERER---QRQKEREKAGSSAIPSLI------PANLHVL-----IDEGN-QPSAPDLGLLD 187
             |.|:|::|   |:||:.|:....|...:|      ...|.::     :|.|. .|..|||....
  Rat   140 QELEKEKQRVAQQKQKQLEQEQFHAFEKMIQKQELEKERLKIVQEFGKVDPGPCGPLLPDLEKPC 204

  Fly   188 QVVYPNDFPTGANRSLPGSGLLLPAASEAAADKTTNSKPS----FDRNQKP---SYNRTDSLLAG 245
            ..|.|:.                |.:....:|..|..:|:    .||:.||   |.......:.|
  Rat   205 VDVAPSS----------------PFSPTQTSDCNTTLRPAKPPVVDRSLKPGALSVIENVPTIEG 253

  Fly   246 SLRLVYVPGDTMEVFLKLALANTSKNIETCGVLAGHLSQNQLYITHIITPQQQGTPDSCNTMHEE 310
             ||.:.||.:....||:||.|||:|.|||||||.|.|.:|:..|||::.|:|.|.||.|:|.:||
  Rat   254 -LRHIVVPRNLCSEFLQLASANTAKGIETCGVLCGKLMRNEFTITHVLIPRQNGGPDYCHTENEE 317

  Fly   311 QIFDVQDQMQLITLGWIHTHPTQTAFLSSVDLHTHCSYQIMMPEALAIVCAPKYNTTGFFILTPH 375
            :||.:||.:.|:|||||||||||||||||||||||||||:|:||::||||:||:..||||.|| .
  Rat   318 EIFFMQDDLGLLTLGWIHTHPTQTAFLSSVDLHTHCSYQMMLPESIAIVCSPKFQETGFFKLT-D 381

  Fly   376 YGLDYIAQCRQSGFHPHPNDPPLFMEAQHIRMDNQAKIKVIDLR 419
            |||..|:.|||.|||||..|||||.:..|:.:.::. :.:.|||
  Rat   382 YGLQEISTCRQKGFHPHGRDPPLFCDCSHVTVKDRI-VTITDLR 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2224	NP_001263108.1	USP8_dimer	16..119	CDD:286108	47/104 (45%)
		MPN_AMSH_like	247..419	CDD:163697	101/172 (59%)
Stambp	NP_612540.1	Interaction with CHMP3. {ECO:0000250}	1..127		53/116 (46%)
		USP8_dimer	12..114	CDD:286108	46/102 (45%)
		Interaction with STAM1. {ECO:0000250}	227..231		1/4 (25%)
		MPN_AMSH_like	254..424	CDD:163697	101/172 (59%)
		JAMM motif. {ECO:0000255|PROSITE-ProRule:PRU01182}	335..348		13/13 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C330527843
eggNOG	1	0.900				E1_COG1310
Hieranoid	1	1.000
Homologene	1	1.000				H4719
Inparanoid	1	1.050	325	1.000	Inparanoid score	I2367
OMA	1	1.010
OrthoDB	1	1.010				D411229at2759
OrthoFinder	1	1.000				FOG0001631
OrthoInspector	1	1.000				T618534
orthoMCL	1	0.900				OOG5_130679
Panther	1	1.100			LDO	PTHR12947
Phylome	1	0.910		0.800	Consistency score
TreeFam	1	0.960
	13	12.770