DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15531 and Scd3

DIOPT Version :9

Sequence 1:	NP_651780.1	Gene:	CG15531 / 43592	FlyBaseID:	FBgn0039755	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_077770.1	Gene:	Scd3 / 30049	MGIID:	1353437	Length:	359	Species:	Mus musculus

Alignment Length:	307	Identity:	93/307 - (30%)
Similarity:	153/307 - (49%)	Gaps:	27/307 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 DQSGDSIHKKRDAIWPLVLFYIHLNILGVYGIYVLLTSASWATILFTALLTLLGTLGVTVGVHRL 74
            |:.|..  .|.:.:|..::....|::..:||| .|:.|....|.||..:..::...|:..|||||
Mouse    61 DEEGPP--PKLEYVWRNIILMALLHVGALYGI-TLVPSCKLYTCLFAFVYYVISIEGIGAGVHRL 122

  Fly    75 WAHRTFTASKPLKVFLMFCQTTAGQGSIYSVVQAHRLHHAKFQQDEDPYYSKHSFMYAQVRGGLL 139
            |:|||:.|..||::||:...|.|.|..:|...:.||.||...:...||:.|:..|.::.|...|:
Mouse   123 WSHRTYKARLPLRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLV 187

  Fly   140 KYSPQQEELLKDVDMSDLESDPVVMFQKRFY---VLLYIFLNVLLSVNTPFQYFGDSLATSMFVG 201
            :..|..:|....:|||||:::.:||||:|:|   :||..|   :|....|:..:|::...|.:|.
Mouse   188 RKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGILLMCF---ILPTLVPWYCWGETFLNSFYVA 249

  Fly   202 FWLRSLIVINLGNLVHSSHFIWSIHKGFKPTDSN---------SIFLITKSYWPQYHYLLPRDYQ 257
            ..||..:|:|...||:|:..::    |::|.|.|         |:..:.:.: ..||:..|.||.
Mouse   250 TLLRYAVVLNATWLVNSAAHLY----GYRPYDKNIDPRQNALVSLGSMGEGF-HNYHHAFPYDYS 309

  Fly   258 SGEYGNYASGIGSSMIRVFAALDWAKDLKTIGSVAVRQGLTKAVETG 304
            :.|| .:.....:..|...|||..|.|.|.:....|   |.:...||
Mouse   310 ASEY-RWHINFTTFFIDCMAALGLAYDRKRVSKATV---LARIKRTG 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15531	NP_651780.1	Delta9-FADS-like	49..286	CDD:239582	78/248 (31%)
Scd3	NP_077770.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..34
		Delta9-FADS-like	97..337	CDD:239582	78/248 (31%)
		FA_desaturase	102..306	CDD:278890	66/211 (31%)
		Histidine box-1. /evidence=ECO:0000305	120..125		4/4 (100%)
		Histidine box-2. /evidence=ECO:0000305	157..161		2/3 (67%)
		Histidine box-3. /evidence=ECO:0000305	298..302		1/3 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1398
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D971318at2759
OrthoFinder	1	1.000	-	-		FOG0000495
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11351
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X207
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.880