DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9747 and Scd

DIOPT Version :9

Sequence 1:	NP_001287604.1	Gene:	CG9747 / 43591	FlyBaseID:	FBgn0039754	Length:	461	Species:	Drosophila melanogaster
Sequence 2:	NP_631931.2	Gene:	Scd / 246074	RGDID:	621176	Length:	358	Species:	Rattus norvegicus

Alignment Length:	356	Identity:	161/356 - (45%)
Similarity:	220/356 - (61%)	Gaps:	30/356 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 PPRGKLQLPPKREELPRSVVPKEIANHVPKDAIDLEEYTRTFVGDRVLGWQFQ----APLK---- 108
            ||.|.||  ..||::.:          ||   :.|||..|..:.:.:....:|    .|.|
  Rat    22 PPSGNLQ--NGREKMKK----------VP---LYLEEDIRPEMREDIHDPSYQDEEGPPPKLEYV 71

  Fly   109 WDKVIQISLLHIVA--GICLLTYPLRELNPYTTIWSFFVGGVAGFGVTAGAHRFWTHKSYKANTV 171
            |..:|.::|||:.|  ||.|:  |..::  ||.:|..|...::..|:||||||.|:|::|||...
  Rat    72 WRNIILMALLHVGALYGITLI--PSSKV--YTLLWGIFYYLISALGITAGAHRLWSHRTYKARLP 132

  Fly   172 LRSILMVCYCVAGQNTLYDWVRDHRVHHKYSETDADPHNANRGFFFSHVGWLMMLKHPEVLRRGR 236
            ||..|::...:|.||.:|:|.||||.|||:|||.|||||:.|||||||||||::.|||.|..:|.
  Rat   133 LRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGG 197

  Fly   237 QIDMSDILADPVVRFHQKYFIPLKTFFCFILPTVIPVYCWGETWTLAFIQQCLFRYVSSLNFTWS 301
            ::||||:.|:.:|.|.::|:.|.....||||||::|.||||||:..:.......||...||.||.
  Rat   198 KLDMSDLKAEKLVMFQRRYYKPGLLLMCFILPTLVPWYCWGETFLHSLFVSTFLRYTLVLNATWL 262

  Fly   302 VNSAAHLWGSRPYDKRIMPSENIYVSLLAMGEGWHNYHHVFPWDYKAAELGNYTVNFTTMVLDAF 366
            |||||||:|.|||||.|...|||.|||.|:|||:|||||.||:||.|:|. .:.:||||..:|..
  Rat   263 VNSAAHLYGYRPYDKNIQSRENILVSLGAVGEGFHNYHHAFPYDYSASEY-RWHINFTTFFIDCM 326

  Fly   367 HKLGWAWNMKQPSKELVRRTLEKYGDGTHAS 397
            ..||.|::.|:.||..|...:::.|||:|.|
  Rat   327 AALGLAYDRKKVSKAAVLARIKRTGDGSHKS 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9747	NP_001287604.1	Delta9-FADS-like	135..376	CDD:239582	126/240 (53%)
CG9747	NP_001287604.1	FA_desaturase	140..343	CDD:278890	110/202 (54%)
Scd	NP_631931.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	8..33		6/12 (50%)
		Delta9-FADS-like	99..336	CDD:239582	125/237 (53%)
		FA_desaturase	100..305	CDD:278890	111/204 (54%)
		Histidine box-1. /evidence=ECO:0000305	119..124		3/4 (75%)
		Histidine box-2. /evidence=ECO:0000305	156..160		2/3 (67%)
		Histidine box-3. /evidence=ECO:0000305	297..301		3/3 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	55	1.000	Domainoid score	I10831
eggNOG	1	0.900	-	-		E1_COG1398
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63267
OrthoDB	1	1.010	-	-		D296120at33208
OrthoFinder	1	1.000	-	-		FOG0000495
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11351
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X207
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.930