Protein Alignment Mlc2 and Calm2

DIOPT Version :10

• Sequence 1: NP_524586.1
• Gene: Mlc2 / 43587
• FlyBaseID: FBgn0002773
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_031615.1
• Gene: Calm2 / 12314
• MGIID: 103250
• Length: 149
• Species: Mus musculus
• Alignment Length: 147
• Identity: 52/147 - (35%)
• Similarity: 81/147 - (55%)
• Gaps: 9/147 - (6%)

  Fly    73 SQKQIAEFKEAFQLMDADKDGIIGKNDLRAAFDSVGKIANDKELDAMLGE----ASGPINFTQLL 133
            :::|||||||||.|.|.|.||.|...:|.....|:|:...:.||..|:.|    .:|.|:|.:.|
Mouse     6 TEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 70

  Fly   134 TLFANRMATSGANDEDEVVIAAFKTFDND--GLIDGDKFREMLMNFGDKFTMKEVDDAYDQMVID 196
            |:.|.:|..:   |.:|.:..||:.||.|  |.|...:.|.::.|.|:|.|.:|||:...:..||
Mouse    71 TMMARKMKDT---DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADID 132

  Fly   197 DKNQIDTAALIEMLTGK 213
            ...|::....::|:|.|
Mouse   133 GDGQVNYEEFVQMMTAK 149

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mlc2	NP_524586.1	PTZ00184	73..213	CDD:185504	51/145 (35%)
Calm2	NP_031615.1	PTZ00184	1..149	CDD:185504	51/145 (35%)
		Necessary and sufficient for interaction with PCP4. /evidence=ECO:0000250|UniProtKB:P0DP24	77..149		23/74 (31%)