Protein Alignment AdoR and LOC11175717

DIOPT Version :10

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: XP_061507703.1
• Gene: LOC11175717 / 11175717
• VectorBaseID: AGAMI1_012729
• Length: 809
• Species: Anopheles gambiae
• Alignment Length: 623
• Identity: 124/623 - (19%)
• Similarity: 190/623 - (30%)
• Gaps: 288/623 - (46%)

  Fly    34 DSPSSELNIPYTVFE----------------VLVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVS 82
            |..:.:|.:|..:.|                .|:.:|::|||.|||:.....|:||..||.:::|
Mosquito   191 DPTARQLELPSAMDEHFLIANWQDCVVVILFCLLIVVTVIGNTLVILSVITTRRLRTVTNCFVMS 255

  Fly    83 LAMADLLVGALGIPFAI----LASMGLPRNLHACLFTVSLLVVLCTISIFCLVAVSVDRYWAILY 143
            ||:||.|||...:|.|:    :.|..|...|  |...:||.|:|||.||..|.|:|:|||.|:..
Mosquito   256 LAVADWLVGIFVMPPAVAVHLMGSWQLGWIL--CDIWISLDVLLCTASILSLCAISIDRYLAVTQ 318

  Fly   144 PMAYSRNVRT-RTAIFIISMCWVAGTIVGFLPLFGWHADVNHN-QECLFVEVMDYNYLVFLYFAT 206
            |:.|||..|: |.|:.:|.:.||....:...|:.||:...... .:|.:.:  :..|:||....:
Mosquito   319 PLNYSRRRRSKRLALLMILVVWVLALAITCPPILGWYEPGRRELDQCRYNQ--NEGYVVFSAMGS 381

  Fly   207 IITPALLMLAFYTHIYRVIIK---------------QVR-------------------------- 230
            ...|..:|:..|..|..|:..               :||
Mosquito   382 FFIPMTVMVYVYVRISCVVASRHDKMTEIEVHKKSHRVREPEEDGYQSEQDPIPLSPKRKRSSSQ 446

  Fly   231 ----------------------------------------QIVTMN------------------- 236
                                                    :::.:|
Mosquito   447 LSTATTTYVAQLGPMLDEGVGAGQPPKPAGKRNNHKHGHYELMDLNTTGGSTQSQTTILAAAGNG 511

  Fly   237 ---PASDLSRRSSAA----------------------------VVQVTTPGRGG----------- 259
               |..|.|..|:||                            .|.:..||.|.
Mosquito   512 TGGPTGDTSTASAAAEGHHHHQEQLRQRTYDDGTSLDAIVDDPAVVLAGPGSGSTESNTSTAATT 576

  Fly   260 ----------------------------------------------------------------- 259
                                                                             
Mosquito   577 AAPVSASVNYNKLPSTAELWSSGNSVFNQQSHKPQSHSMASFAGAAGAGSPPNHSQHFHHHHHHH 641

  Fly   260 -------HTGTMLRVLGAA---------------------------------------------- 271
                   |.|.....|.||
Mosquito   642 HHHHHHHHEGRPTAALAAATGGLRRNNTVNTSITTSTCSSVQLVGGRTGGNNIRIHQKSLSSRIS 706

  Fly   272 -RKRDVKATQNLSIIVLFFMICWIPLYTINCIKAFCPDCYVHPKLTLFCIILSHLNSAVNPVLYA 335
             .||:.|.|:.|||:|..|:.||:|.:....|..|.|..:..|||:.|...|..:|||:||.:||
Mosquito   707 SMKRENKTTRTLSIVVGGFIACWLPFFIHYIITPFLPKDWTVPKLSEFFTWLGWINSAINPFIYA 771

  Fly   336 YHLKDFRAALKNLLLKMMGVDIDQQAEA-IHRFSVASQ 372
            ::..|||||...|.|:....:.::...| ||..|:.::
Mosquito   772 FYSVDFRAAFWRLTLRRFFRNSEKAPFANIHNLSMRAR 809

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tmA_Adenosine_R	42..345	CDD:341316	115/585 (20%)
		TM helix 1	43..69	CDD:341316	10/41 (24%)
		TM helix 2	76..103	CDD:341316	12/30 (40%)
		TM helix 3	112..142	CDD:341316	16/29 (55%)
		TM helix 4	156..174	CDD:341316	4/17 (24%)
		TM helix 5	196..225	CDD:341316	7/28 (25%)
		TM helix 6	273..303	CDD:341316	12/29 (41%)
		TM helix 7	313..338	CDD:341316	12/24 (50%)
LOC11175717	XP_061507703.1	None