Protein Alignment Jasper and HDGFL1

DIOPT Version :10

• Sequence 1: NP_651768.1
• Gene: Jasper / 43576
• FlyBaseID: FBgn0039743
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_612641.2
• Gene: HDGFL1 / 154150
• HGNCID: 21095
• Length: 251
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 80/285 - (28%)
• Similarity: 113/285 - (39%)
• Gaps: 83/285 - (29%)

  Fly    10 YSIGDLVFAKVKGYPPWPAKITKSNNNKKYNVYFYGTGETANIKLEDLFPYASNKERFATEKIMK 74
            |..|||||||:|||..|||:|.......:|.|:|:||.|||.:..:.||||...||:|.  |..|
Human     9 YKSGDLVFAKLKGYAHWPARIEHMTQPNRYQVFFFGTHETAFLSPKRLFPYKECKEKFG--KPNK 71

  Fly    75 RAKFIEAIDQIES--------------------------ALRGEDSAPIDLLDGAEPVAPPTTGD 113
            |..|...:.:||:                          |..|::..|.....|.:.:..|  .|
Human    72 RRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHAGGGGDELGKP--DD 134

  Fly   114 GVKTEEPKPEPGPEPATAA-PVAAAAEKPKKSGTRKTKAPPRHVDGDSEAGAELAPPPAKRRVPT 177
            ...|||   |.||...:|. |...|.::||::      ||.:..:.::|..||     |:|
Human   135 DKPTEE---EKGPLKRSAGDPPEDAPKRPKEA------APDQEEEAEAERAAE-----AER---- 181

  Fly   178 EGLATAAAIPAAPAAATPTSSKKSVKKSKPTAAVTPIQKRSRPVNNIRNEMLMVYMPTAKCLGIV 242
                     .||.||||      :|.:..|  .:..::..|.|...                |:|
Human   182 ---------AAAAAAAT------AVDEESP--FLVAVENGSAPSEP----------------GLV 213

  Fly   243 INYKKPESFESAAAEEAWMENARKE 267
            ....:||. |....||...|.|.:|
Human   214 CEPPQPEE-EELREEEVADEEASQE 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jasper	NP_651768.1	PWWP_HRP	10..86	CDD:438959	34/75 (45%)
		LEDGF	320..440	CDD:463284
HDGFL1	NP_612641.2	PWWP	9..89	CDD:470613	36/81 (44%)
		PHA00666	81..>159	CDD:222808	17/82 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..251		44/203 (22%)