DRSC/TRiP Functional Genomics Resources

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Protein Alignment dgt1 and ino80da

DIOPT Version :10

Sequence 1:NP_001287595.1 Gene:dgt1 / 43529 FlyBaseID:FBgn0039710 Length:589 Species:Drosophila melanogaster
Sequence 2:NP_001410255.1 Gene:ino80da / 110440037 ZFINID:ZDB-GENE-091204-416 Length:922 Species:Danio rerio


Alignment Length:765 Identity:151/765 - (19%)
Similarity:236/765 - (30%) Gaps:306/765 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly    30 EQIH-SELVKIKYCANPTYECSLMRIEGYEYCIRHILRDPRSNFRQCSHVYS-NGRKCINAVAKY 92
            :.|| ||:.....|:.....|...|:.||.:||||:|.|..:.|:||.:|.. |.::|.|.:.|.
Zfish     5 KHIHFSEVDNKPLCSYSPKLCKQRRLNGYAFCIRHVLEDKTAPFKQCEYVAKYNSQRCTNPIPKA 69

  Fly    93 DNKKELILTTLCFEHNR------QTQLQKTHMNVGRIRSRVETNETLLHSLSSHINVED-----I 146
            :.::      .|..|.:      :.:.:|....:..:|||.......|:.....:.:.|     .
Zfish    70 EERR------YCNSHLQVLGFIPKKERKKKQDGLEEVRSRAHVESVALNITVPSLALRDTNGLPA 128

  Fly   147 KPEVKKIE----RDDDEIDVVSPHVTPFVTQDHRNSIGHVVESSRKRRRILDYASDSSSNDADPP 207
            .|...::.    .|.|.:|       ||...:..:.    ||.|..:|.....:|...::.....
Zfish   129 SPPCSRLTPMPLLDSDLLD-------PFAFYEEDSD----VEESLLQRPAQRSSSKRKASSTPVI 182

  Fly   208 CLRNTAQ----DIEFYESDHESI-----------------------------------------D 227
            .||.||:    |||.:.:..||.                                         :
Zfish   183 GLRVTARDLEPDIEHFSAVTESCTLPSSPPPPPPSPPQPSQHTERPTYAPLGTVQTLLCKPAPPE 247

  Fly   228 SEDDDPLKHAG--------------------------VFTRAEAVKIAETKLIKLQGLYR----- 261
            |....||..||                          |..|..|.......|::||.|.:     
Zfish   248 SASSVPLPPAGLQNQPVIWRPASPRPLSAHDCPQPRSVALRPAAFTAPPVCLLRLQHLVQLYANR 312

  Fly   262 -------------------------------------------EQISYLQNVLRQRRR------- 276
                                                       .|.|.....|.:|.|       
Zfish   313 QREHGDLFPHLGLDWSEDSADDEDTEELVPLLPQAWRLQERSPHQSSSSDKPLSRRARLAQLCSY 377

  Fly   277 ---KYLHDIRRERELYCSIHDQLKDTPHERKLYEQLKA-LNSYHRRQGVEAVLYKKLKEKRARDA 337
               :|.|..||:|..          :.|.|..|...|| |::..:.....|.|.:||  .|:...
Zfish   378 LQERYKHLCRRDRAA----------SRHSRYRYAFRKALLHAASKDPDCTAQLIQKL--SRSSQT 430

  Fly   338 LYAAKSSSNPK-----CVFTEGGVKCGERTLPCCKHCRKHILEDKRQVLFRACGVE-RSGVVCQE 396
            ...::|::..|     |..:..|..|....||..:||.:|||.::.|.||.:|... ..|..|..
Zfish   431 SSCSRSAAPHKYERTACTGSTKGQSCSNTALPFSRHCFQHILLNRSQQLFSSCTARFADGQQCSV 495

  Fly   397 PVASILEDSSCVLHLTVAPAKRQYIQKFYEVPSTPPVESIFAAGRGLDNFVGED----------- 450
            ||..|       .|.|  |...::.:|                   :|||:..|           
Zfish   496 PVFDI-------THQT--PLCDEHAKK-------------------MDNFLRGDGHRRSQQQQQR 532

  Fly   451 -PRNE--------------------PQ-------PEGDDLLDFAN-----------GIFDFDLDG 476
             ||.:                    ||       |:|:.|:...:           ...:...|.
Zfish   533 RPRKKTKPPALTKKHKKKRRRGPRRPQKPIPPAVPQGNLLMPSLSLPTHHAHVRSPSTPELSADE 597

  Fly   477 V-DDLANSLDDDYSMFLDMDSDLGLAIED--DGVESDPVDLGLEEEGDGGSNDSVGPAESQAQDN 538
            : ||:||.:.       |:.:||.|..||  |.:...|.||                     || 
Zfish   598 LPDDIANEMP-------DIPNDLELNQEDFSDVLPRLPDDL---------------------QD- 633

  Fly   539 LIADNFELEEPSVQDNNELNFDIDESESNVNEVLRLLEGIEHMPWFDALM 588
                 |:|.|..   |.||....:|:|    |::|.|:.:...|  |:|:
Zfish   634 -----FDLFEGK---NGELLPTTEEAE----ELVRALQAMGSYP--DSLV 669

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dgt1NP_001287595.1 zf-C3Hc3H 42..108 CDD:464023 20/66 (30%)
zf-C3Hc3H 354..411 CDD:464023 18/57 (32%)
ino80daNP_001410255.1 zf-C3Hc3H 18..79 CDD:464023 20/66 (30%)
zf-C3Hc3H 453..511 CDD:464023 21/66 (32%)

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