Protein Alignment neo and cut-6

DIOPT Version :10

• Sequence 1: NP_651733.1
• Gene: neo / 43523
• FlyBaseID: FBgn0039704
• Length: 744
• Species: Drosophila melanogaster
• Sequence 2: NP_499400.2
• Gene: cut-6 / 176520
• WormBaseID: WBGene00000853
• Length: 572
• Species: Caenorhabditis elegans
• Alignment Length: 556
• Identity: 117/556 - (21%)
• Similarity: 196/556 - (35%)
• Gaps: 179/556 - (32%)

  Fly   254 SGACELSELDRLTL-AGSQ---------AFQVNDGSDYLENHCVDEPNKLCEFKRLPGRILKTVD 308
            |||....:..|||| .|.|         |..:.||....:   |.||::|          |:..|
 Worm   121 SGATNTGQALRLTLEKGLQGARPGIPKVAIVITDGQSQDD---VSEPSQL----------LRDAD 172

  Fly   309 SVYQEVSSIDECRELCLNSPYRCHSYDYNDTGDMVCRLSHHSRATLADVQEPFLEVPEASTYELT 373
            .:...:...:      |.:.::.|..    ||:.|          .....|.|.::..|....||
 Worm   173 VMVYAIGVTN------LVNVHQLHQM----TGNPV----------RVFTVESFEQLDRALADSLT 217

  Fly   374 SCYNVT--------IECGGGDMLARIRTSKLFNGKVYAKGSPKSCSVDVKSALDFELRMNYHDLE 430
            .....|        |.||...:..:..|.:.|.|.|:              .:|     :|||.|
 Worm   218 WSMCKTEFRPGTPEIICGPDRIGVKASTKQPFEGNVF--------------VMD-----HYHDEE 263

  Fly   431 ----------------------CNVRQ----STAGRYVN-DIIIQHHDMIVTSSDLGLALACQYD 468
                                  |||.:    :..|.:|. .|:...|.:.:|.:|..:.:.|.|.
 Worm   264 CRAGPEKFPDSRSIGLTVPFSACNVHRYRSLNPKGIFVEVSIVFMFHSLFMTKTDQTVKVQCFYM 328

  Fly   469 LTNKSVSNGVDLDVRGDIMPALSEEVIVESPN--VIMRITSRDGSDMMRSAEVGDPLALKFEIVD 531
            ..:|.|:  |.|.|  .::..:..|.|.:.|.  ..:|..:.|| .::|.|.:|:.:..::|.::
 Worm   329 EADKHVT--VPLSV--SMITTVFREQIYQMPQCAYTLRKGAPDG-PIVRFATLGESVYHRWECIE 388

  Fly   532 EQSPYEIFIRELVAMDGVDN---SEITLIDSNGCPTDHFIMG-PIYKGSVSGKMLLSNFDAFKFP 592
            .:...:.....||....|||   ..:.::|||||..|..::. |.|..|:  ::....:..||:.
 Worm   389 VEGADKDTFGMLVHSCYVDNGYGDRVDILDSNGCGLDAVLLSTPDYDTSL--RLATKPYHVFKYA 451

  Fly   593 SSEVVQFRALVTPCMP---SCE----PVQCEQ---EDTSGEFRSLLSYGRKRRSLNTTDDHPRPR 647
            ...|:||:..:|.|:.   .||    |..|::   ||           |....      .||..|
 Worm   452 DRPVLQFQCQITLCLKYDGGCEGITPPQNCKKLPGED-----------GHHHH------HHPEKR 499

  Fly   648 RDIDTSKKSAPSDMLLVQSIQITDKFGFKQDKQESGDFYDGNETTFTANEEGHGFC--------V 704
            |.             ||:  ::.|..|       :.|.:..:.|..    |....|        :
 Worm   500 RK-------------LVR--RLADGVG-------TIDVFTDSVTVL----EQEPACQQPLPYPLI 538

  Fly   705 NA----IGLITAATIFLLTQLAVIAIWTYCYQRRQK 736
            |.    :|:||...||:.    ::.:|....:||.|
 Worm   539 NTNLWIMGIITLTNIFVF----ILTVWFTFRKRRCK 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:459635
		PAN_AP_HGF	211..285	CDD:238532	12/40 (30%)
		PAN_1	294..373	CDD:459635	10/78 (13%)
		ZP	381..615	CDD:214579	61/273 (22%)
cut-6	NP_499400.2	VWA	47..208	CDD:459670	25/119 (21%)
		ZP	233..480	CDD:214579	61/272 (22%)