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Protein Alignment Usp1 and Usp8

DIOPT Version :9

Sequence 1:	NP_651687.3	Gene:	Usp1 / 43462	FlyBaseID:	FBgn0028476	Length:	1078	Species:	Drosophila melanogaster
Sequence 2:	NP_650948.2	Gene:	Usp8 / 42509	FlyBaseID:	FBgn0038862	Length:	896	Species:	Drosophila melanogaster

Alignment Length:	967	Identity:	185/967 - (19%)
Similarity:	297/967 - (30%)	Gaps:	386/967 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 ETTE--INS-QLRQDQQNQEQENPLRQQ--DNSHPPQENPINQ-------------------QEK 62
            :|.|  ||| :.|..||:|..| |:...  .|.....::||.|                   |||
  Fly    98 DTLEEIINSLRHRYAQQHQAPE-PIAPDLVSNGRAGVDSPITQPTQYARLGLITCQDLYRRMQEK 161

  Fly    63 DTL--------QVSVLYPLVVCAQLADSQLVLTADTPKLSPVKKR------------QRRVYVAD 107
            ..|        .....:....||.....:|:    ||.:|..:.:            .|.|..:.
  Fly   162 SVLVMDCRPSADYEASHLTYYCAFNVPEELI----TPGMSAGRLQARLSSSAKASWASRSVKDSV 222

  Fly   108 TLRCYSLRSRQEPATK-------------DP----------LEGGLKQPDVVPPP----PPVQAP 145
            .|..::.:..| |||.             ||          :|||.:...::.|.    |.||||
  Fly   223 VLMDWNTKDAQ-PATNTAISTLLDILKNWDPDVTYRAPIQIVEGGYEYFIMMYPTHCTNPSVQAP 286

  Fly   146 SPT-----PTESTEY------TPPEQFKSEFWNRIEEAQEPKPVGKKRRTPGGLKRTRGNKLLKE 199
            ...     ..:..||      |..|...::.:       .|:|...:...|..   ||.|:  :.
  Fly   287 QQNNNDIETIDDIEYPSIHDITMKEDISAKDF-------RPRPDFNRANKPAA---TRVNE--QG 339

  Fly   200 LEIQSP--ETAAAIAAAQAELNAAGKSGAAGARSSRKRTNTMSLYDRRFQTTTE--ERRVANGYG 260
            :...||  :..|.|...|||.            ..|...|     |.:.:..::  :|:.|.|.|
  Fly   340 ISRPSPPAKPIAEIMRDQAEF------------LQRAEQN-----DEQLEKASKMWKRQAAEGDG 387

  Fly   261 GNAARSVTGSSSNEIESQEPQSHQYYGPNGGSNAAGAGAGLNGSAAALNHAPSMGTLCNIGNSCY 325
            .||.           |.||
  Fly   388 LNAT-----------EDQE---------------------------------------------- 395

  Fly   326 LNSVVYTLRFAPHF-LHNLHHLIQDLNVVQQTIVRQQTARSASLGKNVSAAQLEHARSWSSKDLA 389
                       .|| :..|....||. :|:...:|::.:|...| .||: .||......:::::
  Fly   396 -----------LHFRILQLESKAQDY-IVENNRLREELSRIQEL-HNVT-QQLSQKEVEATRNI- 445

  Fly   390 TSTDQYSGQNGGVNSGNGGSGSSKSTHQSVTEKLHELYNNLHGNEMADSTEPYHADTLLHAIQDV 454
                                 .||...:...::.|||             |....:.||...::.
  Fly   446 ---------------------ESKIRERQRLDEQHEL-------------ERQERERLLAIARET 476

  Fly   455 NATFE----------GNQQQDAHEFLMCVLNCIRETNQSLIKAIGECPEVIANGYIANPDEVDTG 509
            ...::          |...:|.|        .:.::.:||::..|:....||    .|..|:.|
  Fly   477 KKHYKSPTPSGPPSPGRNLEDVH--------VVSDSLESLLQLTGDPDPTIA----PNKAEIPT- 528

  Fly   510 EGQDRTDSTASQNLNAGNGSLATSQTTTTKTSFFSRKSKRKDEVKPSKSTRVQSPLKENSPTAGG 574
                                             |.|..|    .:|....|....:::.||..|.
  Fly   529 ---------------------------------FDRAMK----PQPRNVERTSQRVRDFSPVIGQ 556

  Fly   575 ITGAG-TAHATANSLFYLNTVDLSGASSTSG--------------SASTSASG-VVSTSAALPTP 623
            ..|.| |......:..|:|:: |...|:|..              |.|...:| |:...|||...
  Fly   557 NVGRGLTGLKNLGNTCYMNSI-LQCLSNTPQLTEYCISDKYKNYISRSNKTNGQVIEEVAALIKE 620

  Fly   624 PQATKY----SSD---------------DEMNS---ATVLKDKMRLE------ERIRELN----- 655
            ....:|    |.|               |:.:|   .|:|.|.:..:      .|.||:.
  Fly   621 LWNGQYKCVASRDLRYVVGQYQKIFRGVDQQDSHEFLTILMDWLHSDLQTLHVPRQREMISASEK 685

  Fly   656 --LNFFSSD-------FEGIVVLTTKCLSCETITRQKQGMLDISVPVPISGYDNADLQDKPSTYI 711
              |.|..:.       |.|.:..|.||::|...:...:...::|:.:|            |::.:
  Fly   686 AWLEFTKAKESMILHLFYGQMKSTVKCVACHKESATYESFSNLSLELP------------PNSNV 738

  Fly   712 --QNSCITKEYFRGE--NKYSCNQCTGYTEAIRSISYEVLPRLLVIQLNRF------SGGMEKVS 766
              .|.|:.. ||.||  :.::|..|....:||:.:....||.:||:.|.||      ||...|..
  Fly   739 CQLNQCMDM-YFSGERIHGWNCPSCKTKRDAIKKLDISKLPPVLVVHLKRFYADPSNSGSYMKKQ 802

  Fly   767 TYVPTTFTL------PCFCATCCELGEGNKL--HVYKLYSVITHVGATLTVGHYIAY 815
            .|:  .|.|      |....     .|...:  ..|:||:|..|.| |:..|||.|:
  Fly   803 NYL--RFPLENLDMNPYIAR-----AESRAVTPKTYQLYAVSNHYG-TMEGGHYTAF 851

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Usp1	NP_651687.3	Peptidase_C19	308..819	CDD:470612	113/595 (19%)
Usp8	NP_650948.2	USP8_dimer	2..114	CDD:462647	6/15 (40%)
		RHOD	148..278	CDD:444705	23/134 (17%)
		Smc	<361..>511	CDD:440809	38/268 (14%)
		Peptidase_C19R	564..887	CDD:239139	70/310 (23%)

Information from Original Tools:

Software error:

Can't use an undefined value as an ARRAY reference at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 1034.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.