DRSC/TRiP Functional Genomics Resources

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Protein Alignment Usp1 and Usp1

DIOPT Version :10

Sequence 1:NP_651687.3 Gene:Usp1 / 43462 FlyBaseID:FBgn0028476 Length:1078 Species:Drosophila melanogaster
Sequence 2:NP_001015015.1 Gene:Usp1 / 313387 RGDID:1306461 Length:784 Species:Rattus norvegicus


Alignment Length:902 Identity:199/902 - (22%)
Similarity:340/902 - (37%) Gaps:224/902 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   229 ARSSRKRTNTMSL--YDRR-------FQTTTEERRVANGYGGNAARSVTGSSSNEIESQEPQSHQ 284
            :|.|..:.|.:||  :.::       |..:.|:...|:.|.|:....|..::.:...|.|.:.  
  Rat    13 SRGSPSKKNRLSLKFFQKKETKRALDFTDSQEDEEKASEYRGSEIDQVVPAAQSSPVSCEKRE-- 75

  Fly   285 YYGPNGGSNAAGAGAGLNGSAAALNHAPSMGTLCNIGNSCYLNSVVYTLRFAPHFLHNLHHLIQD 349
                                    |..|.:| |.|:||:|||||::..|.|.|.|...:.||   
  Rat    76 ------------------------NLLPFVG-LNNLGNTCYLNSILQVLYFCPGFKAGVKHL--- 112

  Fly   350 LNVVQQTIVRQQTARSASLGKNVSAAQLEHARSW----SSKDLATSTDQYSGQNGGVNSGNGGSG 410
            .|::.:   :::..:..|:.|:..:.:.:...|:    |.:.|..|.:|.             ..
  Rat   113 FNIISR---KKEALKDDSIQKDKGSCKEDPLASYELICSLQSLIISVEQL-------------QA 161

  Fly   411 SSKSTHQSVTEKLHELYNNLHGNEMADSTEPYHADTLLHAIQDVNATFEGNQQQDAHEFLMCVLN 475
            |.....:..|::|              :|:|..   ||:.::::|..:||..|.||.|.|.|:|.
  Rat   162 SFLLNPEKYTDEL--------------ATQPRR---LLNTLRELNPMYEGYLQHDAQEVLQCILG 209

  Fly   476 CIRETNQSL----IKAIGECPEVIANGYIANPDEVDTGEGQDRTDSTAS-----QNLNAGN---- 527
            .|:||.|.|    ||.:.|....:....:..  |...|.....||||.:     :.|..||    
  Rat   210 NIQETCQLLKKEEIKNLTEFSSKVEEKSLQK--EETGGISSTETDSTRNLDDLKEQLPKGNWKRK 272

  Fly   528 -----GSL-------------------------ATSQTTTTKTSFFSRKSKRKDEVKPS-KSTRV 561
                 |::                         ||..|.........:.....:..||| |.::|
  Rat   273 SDGESGNMKKKVKLSRESQPLEENQRQTRSKRKATGDTLEASPKIIPKCVSENESAKPSQKKSKV 337

  Fly   562 Q----SPLKENSPTAGGITGAG--TAHATANSLFYLNTVDLSGASSTSGSAST-SASGVVSTSAA 619
            :    .|..:...........|  |.:..:.....:|..||.......|..:| :.||..|..::
  Rat   338 KINWLKPATKQPSILSKFCSLGKITTNQRSKGQPKVNEGDLEEDLEKDGRDNTVNGSGPASPGSS 402

  Fly   620 LPTPPQATKYSSDDEMNSATVLKDKMRLEERIRELNLNFFSSDFEGIVVLTTKCLSCETITRQKQ 684
            : ||..:::..|               :.:...::........|:|.:||.|:||.||::|.:::
  Rat   403 V-TPVDSSEAKS---------------INKGAEQIGFELVEKLFQGQLVLRTRCLECESLTERRE 451

  Fly   685 GMLDISVPVPISGY----DNADLQDKPSTYIQ------NSCITKEYFRGENKYSCNQCTGYTEAI 739
            ...||||||.....    :::::..:|.|.::      :...:.|...||:||.|..|..||||.
  Rat   452 DFQDISVPVQEDELSKVEESSEISPEPKTEMKTLRWAISQFASVERIVGEDKYFCENCHHYTEAE 516

  Fly   740 RSISYEVLPRLLVIQLNRFS----------GGMEKVSTYVPTTFTLPCFCATCCELGEGNKLHV- 793
            ||:.::.:|.::.|.|..|:          ||:.|::|.:.|...|        .|.|.:.... 
  Rat   517 RSLLFDKMPEVITIHLKCFAASGLEFDCYGGGLSKINTPLLTPLKL--------SLEEWSTKPTN 573

  Fly   794 --YKLYSVITHVGATLTVGHYIAYTCFLDLASDYVNCPKDRRNTMTNSQTMASQAVPSNENAAPN 856
              |.|::|:.|.|.|::.|||.|.....||.|    ...|:.|.:.:......:..|.||..|  
  Rat   574 DSYGLFAVVMHSGITISSGHYTASVKVTDLNS----LELDKGNFVVDQMCEIGKPEPLNEEEA-- 632

  Fly   857 NGSSSVASTPVIAAASALASSGNILMKKM-----KFGRSKASSSGDMSKNVKQVNGIISKNITNG 916
            .|::......|.......|....:|.||.     ..|..|:.:..::.........::....|:.
  Rat   633 RGTAENYDDEVSIRVGGNAQPSKVLNKKNVEGIGLLGGQKSKADYELCSKASNPEKVVGTPFTDS 697

  Fly   917 IGKLSISTTCQGVNCCAMRLCCTQQTSSSNSTSCSDFSEESL-QNGSNSNLSFGGSGSTYPTGYG 980
                                 ...:|:.:|.|..||.|:||. |.|.|.      ||......| 
  Rat   698 ---------------------RNSETNDTNGTQESDRSKESSDQTGINV------SGLENKISY- 734

  Fly   981 STGRGGVRANYAHGGPDPIWYMCDDDKIKAMTQREFEELLSPTRKITITPYLLFYAR 1037
                 .|::...:.|.   |.:.||.::|...:::|...|||:...|.|||||||.:
  Rat   735 -----VVQSLKEYEGK---WLLFDDSEVKVTEEKDFLNSLSPSTSPTSTPYLLFYKK 783

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Usp1NP_651687.3 Peptidase_C19 308..819 CDD:470612 136/588 (23%)
Usp1NP_001015015.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21 2/7 (29%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 33..54 5/20 (25%)
Peptidase_C19 82..>253 CDD:470612 39/174 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 232..341 35/152 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 363..411 12/50 (24%)
Peptidase_C19O <424..599 CDD:239136 52/197 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 686..723 1/36 (3%)

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