DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Usp1 and usp-48

DIOPT Version :9

Sequence 1:	NP_001263061.1	Gene:	Usp1 / 43462	FlyBaseID:	FBgn0028476	Length:	1078	Species:	Drosophila melanogaster
Sequence 2:	NP_001361851.1	Gene:	usp-48 / 172782	WormBaseID:	WBGene00009267	Length:	1264	Species:	Caenorhabditis elegans

Alignment Length:	371	Identity:	75/371 - (20%)
Similarity:	127/371 - (34%)	Gaps:	100/371 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   544 SRKSKRKDEVKPSKSTRVQSPLKENSPTAGGITGAGTAHATANSLFYLNTVDLS------GASST 602
            :::.:.|:|.|..:..|     ..|...||.|.|....:..:....:.|..:..      ..|..
Worm    85 TQEQETKEEAKKDQKRR-----DLNDQPAGLINGGNFCYVNSFLQVWFNVPEFRQLIYDFRPSEN 144

  Fly   603 SGSASTSASGVVSTSAALPT---PPQATKYSSDDEMNSATVLKDKMRL---EERIRELNLNFFSS 661
            ..........|.:|..||..   ..|.|.::..|:.::   |...:||   ::..:|..|.||::
Worm   145 FVPPEAPRMNVQATMLALQDIFYTLQTTPFNETDKTSN---LGKLLRLNSEQQDSQEFGLKFFNA 206

  Fly   662 DFEGIVVLTTKCLS-------------------------CETITRQKQGMLDISVPVPISGYDNA 701
                    ..:||.                         |:...|.::....||:.:.|.||  .
Worm   207 --------LERCLPDHPNGKETLKRLKDLFTGETCTRIVCKCGQRSEREETAISLTLNIEGY--C 261

  Fly   702 DLQDKPSTYIQNSCITKEYFRGE---NKYSCNQCTGYTEAIRSISYEVLPRLLVIQLNRF---SG 760
            .|.|....|.           ||   :.:.|::|....:..:...|..||.::||||||:   |.
Worm   262 TLLDALDAYF-----------GEEHLDDFKCSKCNKTGDVSKQSDYVKLPPVIVIQLNRYKYTSK 315

  Fly   761 GMEKVSTYV--PTTFTLPCFCATCCELGEGNKL----HVYKLYSVITHVGATLTVGHYIAYTCFL 819
            |.:|:.|.:  |.......|..|      .|.:    .:|.|::|..|.|.....|||.
Worm   316 GRQKLKTPMAYPREIPAKAFQRT------NNSIPPPAEMYDLFAVTIHEGNNAECGHYY------ 368

  Fly   820 DLASDYVNCPKDRRNTMTNSQTMASQAVPSNENAAPNNGSSSVAST 865
                |.:..|.:::....|.:  |.:|:|.    .|.....:.|.|
Worm   369 ----DLIKSPLNQKWYRYNDE--AIEAIPK----PPGTEKPTTAKT 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Usp1	NP_001263061.1	Peptidase_C19	308..819	CDD:271592	66/323 (20%)
usp-48	NP_001361851.1	UCH	108..394	CDD:395355	67/331 (20%)
usp-48	NP_001361851.1	Ubiquitin_like_fold	1161..1264	CDD:421700
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167414
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930