Protein Alignment superdeath and LAP2

DIOPT Version :10

• Sequence 1: NP_651674.3
• Gene: superdeath / 43444
• FlyBaseID: FBgn0039640
• Length: 999
• Species: Drosophila melanogaster
• Sequence 2: NP_014353.1
• Gene: LAP2 / 855682
• SGDID: S000004990
• Length: 671
• Species: Saccharomyces cerevisiae
• Alignment Length: 773
• Identity: 155/773 - (20%)
• Similarity: 263/773 - (34%)
• Gaps: 264/773 - (34%)

  Fly   105 TPKYD-------RDVRLPHSIRPLKYNITIEPQLSGNFTFAGSVQIRIRVLEDCYNITMHAEELN 162
            :|:||       :|..:.|:  .|..:::.|..     ..:|||..:::.|.:..|   .::||:
Yeast    53 SPEYDQSTLSNYKDFAVLHT--DLNLSVSFEKS-----AISGSVTFQLKKLHEGKN---KSDELH 107

  Fly   163 ISRSDASVHRVQNNG-----------EPEGDGLRIHKQYLVGAKQFFVIELY----DKLLKDVEY 212
            :..|...|..|..:|           ||.|..|.|:.   ......|.:.:.    ||...
Yeast   108 LDTSYLDVQEVHIDGSKADFQIEQRKEPLGSRLVINN---ASCNDNFTLNIQFRTTDKCTA---- 165

  Fly   213 VVHLRFDGIIEDYLQGFYRSSYEVHNETRWVASTQFQATDARRAFPCFDEPALKANFTLHIARPR 277
                         ||  :.:|.:......:|.| |.:|..||..|||||.|::|:.||..|..|
Yeast   166 -------------LQ--WLNSKQTKGGKPYVFS-QLEAIHARSLFPCFDTPSVKSTFTASIESP- 213

  Fly   278 NMTTISNMPIVSSN---DHATMPSYVWDHFAESLPMSTYLVAYAISDFTHISSG-NFAVWARADA 338
                   :|:|.|.   :..:..:.:: .|.:.:|:..||:..|..|.:....| ...|:.....
Yeast   214 -------LPVVFSGIRIEDTSKDTNIY-RFEQKVPIPAYLIGIASGDLSSAPIGPRSTVYTEPFR 270

  Fly   339 IKSAEYALSVGPRILTFLQDFFNVTFP--------LPKIDMIALPEFQAGAMENWGLITFRETAM 395
            :|..::...  ..:..|:|....:.|.        |..:|     .:..|.||:..: ||....:
Yeast   271 LKDCQWEFE--NDVEKFIQTAEKIIFEYEWGTYDILVNVD-----SYPYGGMESPNM-TFATPTL 327

  Fly   396 LYDPGVATANNKQRVASVVGHELAHQWFGNLVTPSWWSDIWLNEGFASYMEYLTADAVAPE---- 456
            :       |:::..: .|:.|||||.|.|||||...|:..|||||:..|:|.....|:..|
Yeast   328 I-------AHDRSNI-DVIAHELAHSWSGNLVTNCSWNHFWLNEGWTVYLERRIIGAIHGEPTRH 384

  Fly   457 ------WKQLDQFVVNELQAVFQLDALSTSHKISHEVFNPQEISEIFDRISYAKG-------STI 508
                  |..|.    |.:.::...:..||..:..::..:|   .:.|..:.|.||       .||
Yeast   385 FSALIGWSDLQ----NSIDSMKDPERFSTLVQNLNDNTDP---DDAFSTVPYEKGFNLLFHLETI 442

  Fly   509 IRMMAHFLTNPIFRRGLSKYLQEMAYNSATQDDLWHFLTVEAKSSGLLDDSRSVKEIMD-----T 568
            :...|.|  :|..|....|:.::........|.|:.|...:             |||:|     |
Yeast   443 LGGKAEF--DPFIRHYFKKFAKKSLDTFQFLDTLYEFYPEK-------------KEILDSVDWET 492

  Fly   569 WTLQTGYPVVKVSRHPNSDVIRLEQVRFVYTNTTREDESLLWYIPITFTTDSELNFANTRPTTWM 633
            |..:.|.|               .:..|                 ||...|:
Yeast   493 WLYKPGMP---------------PRPHF-----------------ITALADN------------- 512

  Fly   634 PRTKLYELENRELSLAKWFIFNVQQTGYYRVNYDLENWMAITEHLMDVDNFE------DIAPANR 692
                :|:|.::                          |:.:.:||...::|.      ||...|.
Yeast   513 ----VYQLADK--------------------------WVEMAQHLKTTEDFRSEFNAIDIKDFNS 547

  Fly   693 AQLIDDVMNLARGSYLSYETAMNLTRYLGHELGHVPWKAAISNFIFIDSMFVNSGDYDLLK-NYL 756
            .||:           |..||   ||     :.||...|..               |:|..| ...
Yeast   548 NQLV-----------LFLET---LT-----QNGHSNKKPK---------------DFDWAKFPVA 578

  Fly   757 LKQLKKVYDQVGFKDSQDESEDILVKLKRADILSMACHLGHQECIAEASRHFQNWMQT 814
            .:.|..:|            :|.:||.:.|:::...........:.|..:|..:|:.|
Yeast   579 SRALLDIY------------QDNIVKSQNAEVVFKMFKFQIFAKLQEEYKHLADWLGT 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
superdeath	NP_651674.3	M1_APN-Q_like	121..571	CDD:341064	112/498 (22%)
		ERAP1_C	651..976	CDD:463368	30/171 (18%)
LAP2	NP_014353.1	leuko_A4_hydro	57..669	CDD:274120	153/769 (20%)