Protein Alignment superdeath and Erap1

DIOPT Version :10

• Sequence 1: NP_651674.3
• Gene: superdeath / 43444
• FlyBaseID: FBgn0039640
• Length: 999
• Species: Drosophila melanogaster
• Sequence 2: XP_006231762.1
• Gene: Erap1 / 80897
• RGDID: 708542
• Length: 954
• Species: Rattus norvegicus
• Alignment Length: 956
• Identity: 321/956 - (33%)
• Similarity: 503/956 - (52%)
• Gaps: 112/956 - (11%)

  Fly   111 DVRLPHSIRPLKYNITIEPQLSGNFTFAGSVQIRIRVLEDCYNITMHAEELNISRSDASVHRVQN 175
            ::|||..|.|:.|::.|...|| ..||.|..::.|.|.:....|.||:.:|.||:  |::.|...
  Rat    40 NMRLPEYITPIHYDLMIHANLS-TLTFWGKTEVEITVSQPTSTIIMHSHQLQISK--ATLRRGAE 101

  Fly   176 NGEPEGDGLRI-----HKQYLVGAKQFFVIELYDKLLKDVEYVVHLRFDGIIEDYLQGFYRSSYE 235
            ...|| :.|::     |:|..:...|        .||....|.|.:.:...:.:...|||:|:|.
  Rat   102 EMLPE-EPLKLMEYSAHEQVALLTAQ--------PLLAGSVYTVIITYAANLSENFHGFYKSTYR 157

  Fly   236 V-HNETRWVASTQFQATDARRAFPCFDEPALKANFTLHIAR-PRNMTTISNMPIVSSNDHATMPS 298
            . ..|.|.:|:|||:.|.||.||||||||||||:|::.|.| ||:: .|||||:|.|...|  ..
  Rat   158 TQEGERRILAATQFEPTAARMAFPCFDEPALKASFSIKIKRDPRHL-AISNMPLVKSVTVA--EG 219

  Fly   299 YVWDHFAESLPMSTYLVAYAISDFTHIS----SG-NFAVWARADAIKSAEYALSVGPRILTFLQD 358
            .:.|||..::.|||||||:.||||..:|    || ..:|:|..|.|..|:|||.....:|.|.:|
  Rat   220 LIEDHFDITVKMSTYLVAFIISDFKSVSKMTKSGVKVSVYAVPDKINQADYALDAAVTLLEFYED 284

  Fly   359 FFNVTFPLPKIDMIALPEFQAGAMENWGLITFRETAMLYDPGVATANNKQRVASVVGHELAHQWF 423
            :|::.:||||.|:.|:|:||:||||||||.|:||:|:|||...::|::|..:...|.||||||||
  Rat   285 YFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLYDKEKSSASSKLGITMTVSHELAHQWF 349

  Fly   424 GNLVTPSWWSDIWLNEGFASYMEYLTADAVAPEWKQLDQFVVN----------------ELQAVF 472
            |||||..||:|:|||||||.:||:::.....||.|.:.....|                |.:..|
  Rat   350 GNLVTMEWWNDLWLNEGFAKFMEFVSVTVTHPELKVMQILTANHQNEPEDLSGRAMERTEEEYFF 414

  Fly   473 -------QLDALSTSHKISHEVFNPQEISEIFDRISYAKGSTIIRMMAHFLTNPIFRRGLSKYLQ 530
                   ::|||::||.:|..|.||.:|.|:||.:||.||:.|:.|:..:|:...|:||:.:|||
  Rat   415 GKCFNAMEVDALNSSHPVSTPVENPAQIREMFDEVSYEKGACILNMLRDYLSADTFKRGIVQYLQ 479

  Fly   531 EMAYNSATQDDLWHFLTVEAKSSG--LLDD--SRS---------------VKEIMDTWTLQTGYP 576
            :.:|.:...:|||:.:.....:.|  .:|.  ||:               :|.:|:|||||.|:|
  Rat   480 KYSYKNTKNEDLWNSMMHICPTDGTQTMDGFCSRNQHSSSTSHWRQEVIDIKSMMNTWTLQKGFP 544

  Fly   577 VVKVS-RHPNSDVIRLEQVRFVYTNTTREDESLLWYIPITFTT---DSELNFANTRPTTWMPRTK 637
            ::.:: |..|   :.|:|..::..:....:...||::|:||.|   ||...|        :.:||
  Rat   545 LITITVRGRN---VHLKQEHYMKGSECFPETGSLWHVPLTFITSKSDSVQRF--------LLKTK 598

  Fly   638 LYELENRELSLAKWFIFNVQQTGYYRVNYDLENWMAITEHLMDVDNFEDIAPANRAQLIDDVMNL 702
            ...:...|  ..:|..|||...|||.|:|..:.|.::...|.:...  .|:..:||.||::...|
  Rat   599 TDVIILPE--AVEWIKFNVGMNGYYIVHYGDDGWASLNGLLKEAHT--TISSNDRASLINNAFQL 659

  Fly   703 ARGSYLSYETAMNLTRYLGHELGHVPWKAAISNFIFIDSMFVNSGDYDLL------KNYLLKQLK 761
            .....||.|.|::|..||.:|...:|....::..|   .|:......|::      |::||:.||
  Rat   660 VSIGKLSIEKALDLILYLKNETEIMPIFQGLNELI---PMYKLMEKRDMVEVETQFKDFLLRLLK 721

  Fly   762 KVYDQVGFKDSQDESEDILVKLKRADILSMACHLGHQECIAEASRHFQNWMQTPNPDSNNPIVPN 826
            .:.::..:.|....||.:|    |:.:|.:||...:|.|:..|.|:|:.| :..|.:.:.||...
  Rat   722 DLINKQTWTDEGSVSERML----RSQLLLLACVHRYQLCVQRAERYFREW-KASNGNMSLPIDVT 781

  Fly   827 LRGVVYCSAIQYGTEYEWDFAFERFLKTNVPGEKDLLLNALGCSKEPWLLYRFLRRGISGQHIRK 891
            |  .|:....| .|| .|||.:.::..:....||..:..:|..|::|..|...|.:...|:.|:.
  Rat   782 L--AVFAVGAQ-NTE-GWDFLYSKYQSSLSSTEKSQIEFSLCISQDPEKLQWLLDQSFKGEIIKT 842

  Fly   892 QDLFRVFAAVSTTVVGQNIAFDFLRNNWQEI--KTYMGSQMSSIHTLFKFATKGFNSKFQLGEFE 954
            |:...:...:....||..:|:.||:.||.:|  |..:||  |||..:....|..|:::.:|.|.:
  Rat   843 QEFPHILTLIGRNPVGYPLAWKFLKENWNKIVQKFELGS--SSIAHMVMGTTNQFSTRARLEEVK 905

  Fly   955 NFVKD--AHWDYDRPVQQIVEHIETSVDWMNKNYKSIVRWLENEAQ 998
            .|...  .:....|.|||.:|.||.::.||:||:..|..||:.|.|
  Rat   906 GFFSSLKKNGSQLRCVQQTIETIEENIRWMDKNFDKIRLWLQKERQ 951

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
superdeath	NP_651674.3	M1_APN-Q_like	121..571	CDD:341064	191/503 (38%)
		ERAP1_C	651..976	CDD:463368	93/334 (28%)
Erap1	XP_006231762.1	M1_APN-Q_like	50..539	CDD:341064	191/503 (38%)
		ERAP1_C	610..929	CDD:463368	93/334 (28%)