Protein Alignment superdeath and Lvrn

DIOPT Version :10

• Sequence 1: NP_651674.3
• Gene: superdeath / 43444
• FlyBaseID: FBgn0039640
• Length: 999
• Species: Drosophila melanogaster
• Sequence 2: NP_083284.1
• Gene: Lvrn / 74574
• MGIID: 1921824
• Length: 991
• Species: Mus musculus
• Alignment Length: 1053
• Identity: 320/1053 - (30%)
• Similarity: 498/1053 - (47%)
• Gaps: 156/1053 - (14%)

  Fly    25 SRPMNAATPTTTTTFSKGGRRYSVSLTTAILLASFFICTLLAVGFIVYNFATCAELEPD------ 83
            |||           ||.|   ..||...|:|||:.....||.:..:...:.:||.::|.
Mouse     2 SRP-----------FSSG---VYVSRGVALLLAALTAVLLLVLVALASLYGSCAHVQPSEQGNSR 52

  Fly    84 -------------------SDEDVVCTSYHLRRLKAGHDDTPKYDRDVRLPHSIRPLKYNITIEP 129
                               :.|..|.||..|     |....| :|. :|||..:.||.|::.:.|
Mouse    53 VKNTSLWPPGGQEWALPTPAQEPTVGTSQDL-----GPPSGP-WDH-LRLPPWLVPLHYDLELWP 110

  Fly   130 QLS------GNFTFAGSVQIRIRVLEDCYNITMHAEELNISR-----------SDASVHRVQNNG 177
            .|.      .|.||.|.|.|.:|.......:.:|:..||..:           .:|:|.|||
Mouse   111 WLQPDKLSPPNLTFTGRVNITVRCTVASSRLLLHSFLLNYKQVEVWGPLAQDTRNATVGRVQ--- 172

  Fly   178 EPEGDGLRIHKQYLVGAKQFFVIELYDKLLKDVEYVVHLRFDG-IIEDYLQGFYRSSYEVHNETR 241
                    :.|.:.....||.|::|...|.....|.:...|.| :::..|:|.:.:.|...:|.|
Mouse   173 --------VEKVWFAPDMQFVVLDLGQSLEPGSRYELSFHFSGQVLQVGLEGLFLNLYHDEDELR 229

  Fly   242 WVASTQFQATDARRAFPCFDEPALKANFTLHIARPRNMTTISNMPIVSSNDHATMPSYVWD---- 302
            .:.:||.:.|.||..|||||||||||.|.:.:........:||||.:..::...:....|.
Mouse   230 ALVATQMEPTFARHVFPCFDEPALKATFNITVIHHPGYAALSNMPQLGQSERIDVNGSRWTVTTF 294

  Fly   303 HFAESLPMSTYLVAYAISDFTHIS----SGNFAVWARADAIKSA--EYALSVGPRILTFLQDFFN 361
            |....:|  |||||..:.|..|||    .....||||.|.|.|.  ::|.::...|.:||:|.||
Mouse   295 HTTPRMP--TYLVALVVCDLDHISRTERGKEIRVWARKDDIASGYLDFAANITGPIFSFLEDLFN 357

  Fly   362 VTFPLPKIDMIALPEFQAGAMENWGLITFRETAMLYDPGVATANNKQRVASVVGHELAHQWFGNL 426
            :::.|||.|::|||.|.:||||||||:.|.|:::|.:|.......:..:.|::.||:.|||||||
Mouse   358 ISYRLPKTDIVALPIFASGAMENWGLLIFDESSLLLEPEDELTEKRAMILSIIAHEVGHQWFGNL 422

  Fly   427 VTPSWWSDIWLNEGFASYMEYLTADAVAPEWKQLDQFVVNELQAVFQLDALSTSHKISHEVFNPQ 491
            ||.|||::||||||||||.|....:...|:......|....|..:...|....|..:|..|.|..
Mouse   423 VTMSWWNNIWLNEGFASYFELELTNYFYPKVPMNMIFFFTVLHGILGEDHALESRAVSTAVENFT 487

  Fly   492 EISEI---FDRISYAKGSTIIRMMAHFLTNPIFRRGLSKYLQEMAYNSATQDDLWHFLTVEAKSS 553
            |.|||   ||..:|.||:.:..|:|.||:..:|...|..||:..:|::|.|||||..:.:.....
Mouse   488 ETSEINRLFDLYTYKKGACMAWMLASFLSPHLFINALKSYLETFSYSNAEQDDLWRHIQMAIGEQ 552

  Fly   554 GLLDDSRSVKEIMDTWTLQTGYPVVKVSRHPNSDVIRLEQVRFVYTNTTREDESLL-----WYIP 613
            .:.....:||.|||:||.:.|:|::.|  :.::.|::.|.   .|.:.. |:::||     |.:|
Mouse   553 NVTHLPATVKGIMDSWTHRGGFPIITV--NVSTGVVKQEP---FYLDKV-ENQTLLSHNSTWIVP 611

  Fly   614 ITFTTDSELNFANTRPTTWM-------PRTKLYELENRELSLAKWFIFNVQQTGYYRVNYDLENW 671
            |.:     :.....:|..|:       |..||.:      |.:.|.|.|...|||||||||...|
Mouse   612 IFW-----MKNGIPQPLVWLDKSNMMFPGMKLSD------SDSDWVILNFNVTGYYRVNYDELGW 665

  Fly   672 MAITEHLMDVDNFEDIAPANRAQLIDDVMNLARGSYLSYETAMNLTRYLGHELGHVPWKAAISNF 736
            ..::|.| :.|. :.|...||.||:.|...|.:.:|:..|||::||:|:..|...:.|...:.|.
Mouse   666 KKLSEQL-EKDP-KAIPVINRLQLVSDAFALTKNNYIEIETALDLTKYIAEEDEILVWFEVLLNL 728

  Fly   737 IFIDSMF-VNS-GDYDLLKNYLLKQLKKVYDQVG--FKDSQDESED---ILVKLKRADILSMACH 794
            |..:.:: ||: ..|.|||.||||:...:::...  .:::....:|   .|..|:|  |...||.
Mouse   729 INREVIYDVNNYALYPLLKKYLLKRFNSIWNTYSAIIRENVASLQDNYLSLFSLER--IFETACW 791

  Fly   795 LGHQECIAEASRHFQNWMQTPNPDSNNPIVPNLRGVVYCSAIQYGTEYEWDFAFERFLKTNVPGE 859
            ||.::|:..:...|:.|  |.:|::..|  |.:...|.|||:..|::.:|||.|..::  |...|
Mouse   792 LGLEDCLQLSRELFKKW--TAHPETAIP--PQIENAVLCSAVALGSDKDWDFLFNLYI--NTTEE 850

  Fly   860 KD-----LLLNALGCSKEPWLLYRFLRRGISGQHIRKQDLFRVFAAVSTTVVGQNIAFDFLRNNW 919
            :|     .|::|:.|||:||:|.||:...|:.......:. .:...|:|:.||:.||.|||.:||
Mouse   851 EDESRRRRLVHAMSCSKDPWILNRFMEYAITAVSSNFSET-NIIVVVATSEVGRYIAKDFLMDNW 914

  Fly   920 QEIKTYMGSQMSSIHTLFKFATKGFNSKFQLGEFENFVKDAHWDYDRPVQQI------------V 972
            ..:....|  |..:..|.....:..::..|:.|.::|......::.|.|.|.            .
Mouse   915 VAVTERYG--MDWLDALVPVLGRTVSTDQQVTELQHFFSTVLEEHQRVVVQAKLQAMKTKNLQNK 977

  Fly   973 EHIETSVDWMNKN 985
            :.|...|:|:.||
Mouse   978 KRIARVVEWLRKN 990

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
superdeath	NP_651674.3	M1_APN-Q_like	121..571	CDD:341064	164/480 (34%)
		ERAP1_C	651..976	CDD:463368	103/348 (30%)
Lvrn	NP_083284.1	M1_APN-Q_like	102..570	CDD:341064	164/480 (34%)
		ERAP1_C	645..964	CDD:463368	102/331 (31%)