Protein Alignment superdeath and RNPEPL1

DIOPT Version :10

• Sequence 1: NP_651674.3
• Gene: superdeath / 43444
• FlyBaseID: FBgn0039640
• Length: 999
• Species: Drosophila melanogaster
• Sequence 2: NP_060696.4
• Gene: RNPEPL1 / 57140
• HGNCID: 10079
• Length: 725
• Species: Homo sapiens
• Alignment Length: 547
• Identity: 133/547 - (24%)
• Similarity: 215/547 - (39%)
• Gaps: 120/547 - (21%)

  Fly   246 TQFQATDARRAFPCFDEPALKANFTLHIARPRNMTTISNMPIVSSNDHATMPSYVWD----HFAE 306
            ||..:...|..|||||.||:|..::..:..|      |.:.::.|   ||..:|:.:    ||..
Human   195 TQGHSVCNRSFFPCFDTPAVKCTYSAVVKAP------SGVQVLMS---ATRSAYMEEEGVFHFHM 250

  Fly   307 SLPMSTYLVAYAISDFTHISSG-NFAVWARADAIKSA--------EYALSVGPRIL-TFLQDFFN 361
            ..|:..||||....|......| ...|||....:.:|        |..||...|:. .::...::
Human   251 EHPVPAYLVALVAGDLKPADIGPRSRVWAEPCLLPTATSKLSGAVEQWLSAAERLYGPYMWGRYD 315

  Fly   362 VTFPLPKIDMIALPEFQAGAMENWGLITFRETAMLYDPGVATANNKQRVASVVGHELAHQWFGNL 426
            :.| ||       |.|...|||| ..:||..:::|       .:::..|..|: ||:||.||||.
Human   316 IVF-LP-------PSFPIVAMEN-PCLTFIISSIL-------ESDEFLVIDVI-HEVAHSWFGNA 363

  Fly   427 VTPSWWSDIWLNEGFASYME-YLTADAVAPEWKQLDQFVVNELQAVFQLDALSTSHKISHE---- 486
            ||.:.|.::||:||.|:|.: .:|.:.....:        ..|:..|:||||....|:..|
Human   364 VTNATWEEMWLSEGLATYAQRRITTETYGAAF--------TCLETAFRLDALHRQMKLLGEDSPV 420

  Fly   487 ---------VFNPQEISEIFDRISYAKGSTIIRMMAHFLTNP-IFRRGLSKYLQEMAYNS-ATQD 540
                     ..||..:..:|   :|.||...:..::....:| .|...|..|:::..:.| ..||
Human   421 SKLQVKLEPGVNPSHLMNLF---TYEKGYCFVYYLSQLCGDPQRFDDFLRAYVEKYKFTSVVAQD 482

  Fly   541 DLWHFLTV--EAKSSGLLDDSRSVKEIMDTWTLQTGYPVVKVSRHPNSDVIRLEQVRFVYTNTTR 603
            .|..||:.  |.|...:  |.|:..| .:.|...||.|:.:......|.:.|..:..|.......
Human   483 LLDSFLSFFPELKEQSV--DCRAGLE-FERWLNATGPPLAEPDLSQGSSLTRPVEALFQLWTAEP 544

  Fly   604 EDESLL---------WYIPITFTT----DSELNFANTRPTTWMPRTKLY----ELENRELSLAKW 651
            .|::..         |.   ||.|    |..|:.:.......|..:|.|    :..|.|:.: :|
Human   545 LDQAAASASAIDISKWR---TFQTALFLDRLLDGSPLPQEVVMSLSKCYSSLLDSMNAEIRI-RW 605

  Fly   652 FIFNVQQTGY---YRVNYDLENWMAITEHLMDVDNFEDIAPA-------------------NRAQ 694
            ....|:...|   :||...||:.|:   .:..:..:||:...                   |..:
Human   606 LQIVVRNDYYPDLHRVRRFLESQMS---RMYTIPLYEDLCTGALKSFALEVFYQTQGRLHPNLRR 667

  Fly   695 LIDDVMNLARGSYLSYETAMNLTRYLG 721
            .|..:::...||  |.|.|...:..||
Human   668 AIQQILSQGLGS--STEPASEPSTELG 692

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
superdeath	NP_651674.3	M1_APN-Q_like	121..571	CDD:341064	96/356 (27%)
		ERAP1_C	651..976	CDD:463368	19/93 (20%)
RNPEPL1	NP_060696.4	M1_LTA4H	29..512	CDD:341062	96/356 (27%)
		Leuk-A4-hydro_C	560..673	CDD:462686	23/119 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	676..699		7/19 (37%)