Protein Alignment superdeath and anpepla

DIOPT Version :10

• Sequence 1: NP_651674.3
• Gene: superdeath / 43444
• FlyBaseID: FBgn0039640
• Length: 999
• Species: Drosophila melanogaster
• Sequence 2: XP_001922987.2
• Gene: anpepla / 555317
• ZFINID: ZDB-GENE-141215-4
• Length: 956
• Species: Danio rerio
• Alignment Length: 988
• Identity: 337/988 - (34%)
• Similarity: 524/988 - (53%)
• Gaps: 75/988 - (7%)

  Fly    43 GRRYSVSLTTAILLASFFICTLLAV-GF-IVYNFATCAELEPDSDEDVV-CTSYHLRRLKAGHDD 104
            |:.:.:|...|.:|.:..:.:||.: |. ::|     |:.:..::|::| .|...|.........
Zfish     2 GKGFYISKPLAFVLLALAVGSLLTILGLSLIY-----AQEKRRNEENMVNNTVTTLAPYSTSIPS 61

  Fly   105 TPKYDRDVRLPHSIRPLKYNITIEPQLS----GNFTFAGSVQIRIRVLEDCYNITMHAEELNISR 165
            ...:|: .|||.::.|..||||:.|:|:    |.:.|.|...:....:::...|.:|:..||.|.
Zfish    62 NEPWDK-YRLPDTLLPEYYNITLWPRLTKDDLGMYIFTGKSGVAFLCVKETDLILIHSSNLNYSL 125

  Fly   166 SDASVHRVQNNGEPEGDGLR---IHKQYLVGAKQFFVIELYDKLLKDVEYVVHLRFDGIIEDYLQ 227
            : |..|..:..|.   .|.|   |.|.:.....:|.||:|.:.|.....|.::..|.|.:.|.|.
Zfish   126 T-AEKHHAELMGL---GGTRAPVILKTWFQDQTEFMVIQLRENLQVGKSYWLYTEFQGELADDLG 186

  Fly   228 GFYRSSYEVHNETRWVASTQFQATDARRAFPCFDEPALKANFTLHIARPRNMTTISN-MPIVSSN 291
            |||||.|..:...:.||:||.|.|.||.||||||||::||.|.|.:..|.....::| |...:.|
Zfish   187 GFYRSEYVENGVEKVVATTQMQPTAARTAFPCFDEPSMKAVFHLTLIHPPGTVALANGMETGTEN 251

  Fly   292 DHATMPSYVWDHFAESLPMSTYLVAYAISDFTHISSGNFA------VWARADAIKSAE--YALSV 348
            ........:...|..:..|||||:|:.||:|..|.|...|      :|.|.:||::.|  |||:|
Zfish   252 ITIENQQVLQTRFEPTEKMSTYLLAFVISEFPSIQSPLGANKILVRIWGRREAIENGEGDYALNV 316

  Fly   349 GPRILTFLQDFFNVTFPLPKIDMIALPEFQAGAMENWGLITFRETAMLYDPGVATANNKQRVASV 413
            ...:|.:|:.::|.|:||.|.|.||||:|.|||||||||:|:|||.:.|:|.|::..:|:.|.:|
Zfish   317 TFPVLKYLESYYNTTYPLSKSDQIALPDFSAGAMENWGLVTYRETFLFYEPKVSSHEDKEGVITV 381

  Fly   414 VGHELAHQWFGNLVTPSWWSDIWLNEGFASYMEYLTADAVAPEWKQLDQFVVNELQAVFQLDALS 478
            :.|||||.|||||||..||:|:|||||||||:.||.||...|.|...:..|:.::...|.:|||.
Zfish   382 ISHELAHMWFGNLVTMRWWNDLWLNEGFASYVSYLAADYAEPTWNIKELMVLQQVYRAFTVDALV 446

  Fly   479 TSHKISHE---VFNPQEISEIFDRISYAKGSTIIRMMAHFLTNPIFRRGLSKYLQEMAYNSATQD 540
            :||.:|..   |..||:|.|:||.::|:||:.::||::.||:..:|.:||..||||.||::....
Zfish   447 SSHPLSSREDAVNTPQQIEELFDAVTYSKGAAVLRMLSEFLSESVFAKGLHNYLQEHAYSNTVYT 511

  Fly   541 DLWHFLTVEAKSSGLLDDSRSVKEIMDTWTLQTGYPVVKVSRHPNSDVIRLEQVRFVY----TNT 601
            |||..|...|.|.|.:....|::|||:.|.||.|:|||.:..|..|    :.|..|:.    ...
Zfish   512 DLWKKLQEVADSDGNVHLPASIEEIMNRWILQAGFPVVTIDTHTGS----ISQQHFLIDPEAVVN 572

  Fly   602 TREDESLLWYIPITFTTDSELNFANTRPTTWMPRTKLYELENRELSLAKWFIFNVQQTGYYRVNY 666
            ...|.:..|::|||:..    |..|......:.::..|||...|   ..|.:.|:..||||||||
Zfish   573 KPSDYNYEWFVPITWMK----NGRNMGQHWLLNKSTSYELMKTE---TNWILANLNVTGYYRVNY 630

  Fly   667 DLENWMAITEHLMDVDNFEDIAPANRAQLIDDVMNLARGSYLSYETAMNLTRYLGHELGHVPWKA 731
            |.:||..:.:.|  ..:.:.|...||.|:|||...|||...|:...|:..|:||.:|..::||::
Zfish   631 DSQNWERLIKQL--TSDHQAIPVLNRGQIIDDAFTLARAKILNITMALRTTQYLSNEKEYIPWES 693

  Fly   732 AISNFIFIDSMFVNSGDYDLLKNYLLKQLKKV--YDQVGFKDSQDESEDILVKLKRADILSMACH 794
            ||.|..:...||..:.....|:.||.::::.:  |.:|...:...:....:.:..:.:.::|||.
Zfish   694 AIRNLEYFFLMFDRTEVRGPLEAYLRRKVEPLFHYFKVITSNWTRKPTRHMDQYNQLNAITMACK 758

  Fly   795 LGHQECIAEASRHFQNWMQTPNPDSNNPIVPNLRGVVYCSAIQYGTEYEWDFAFERFLKTNVPGE 859
            ...:.|....|..::.||:.||.   ||:..:|:.||||:||..|...||||.:..|..:.|..|
Zfish   759 TRVKACSELTSMWYRQWMKDPNV---NPVPSDLKTVVYCNAIAAGGVEEWDFGWAMFKNSTVAAE 820

  Fly   860 KDLLLNALGCSKEPWLLYRFLRRGISGQHIRKQDLFRVFAAVSTTVVGQNIAFDFLRNNWQEIKT 924
            .:.|:..|.|:||||||.|:|...|....|||||:......:::.|:||.:|:||.|..||.:.|
Zfish   821 AEKLMYGLSCTKEPWLLNRYLHYAIDPNLIRKQDVTYPIVYIASNVIGQPLAWDFFRAKWQLMTT 885

  Fly   925 YMGSQMSSIHTLFKFATKGFNSKFQLGEFENFVKD---------AHWDYDRPVQQIVEHIETSVD 980
                   ....|.....|.|:::|||.:.:.|.::         .|     .::|.:|..:.:|.
Zfish   886 -------EFRVLILGIVKTFSTEFQLQQLQRFQEEVAESGVSLGTH-----AIEQAIEQTKANVK 938

  Fly   981 WMNKNYKSIVRWL 993
            |:::|...::.||
Zfish   939 WVSENKVQVMDWL 951

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
superdeath	NP_651674.3	M1_APN-Q_like	121..571	CDD:341064	188/468 (40%)
		ERAP1_C	651..976	CDD:463368	105/335 (31%)
anpepla	XP_001922987.2	M1_APN-Q_like	79..542	CDD:341064	188/466 (40%)
		ERAP1_C	615..935	CDD:463368	105/336 (31%)