Protein Alignment superdeath and Trhde

DIOPT Version :10

• Sequence 1: NP_651674.3
• Gene: superdeath / 43444
• FlyBaseID: FBgn0039640
• Length: 999
• Species: Drosophila melanogaster
• Sequence 2: NP_666353.2
• Gene: Trhde / 237553
• MGIID: 2384311
• Length: 1066
• Species: Mus musculus
• Alignment Length: 1029
• Identity: 322/1029 - (31%)
• Similarity: 517/1029 - (50%)
• Gaps: 104/1029 - (10%)

  Fly    33 PTTTTTFSKGGRRYSVSLTTAILLASFFICTLLAVGFIVYNFATCAELE------------PDSD 85
            |.||.......:|  :.|..|:.:.:....|:||| .:...|..|....            |:.|
Mouse    68 PRTTERHIAVHKR--LVLAFAVSIVALLAVTMLAV-LLSLRFDECGASAAMPGTDGGLGGFPERD 129

  Fly    86 EDVVCTSYHLRRLKAGHDDTPKYDRDV-------------------------RLPHSIRPLKYNI 125
            .:........|...||.:.:.:...:|                         ||...::||.||:
Mouse   130 SNSSFPGSARRNHHAGGESSQRESGEVGTPGTPSAQPPSEEEREQWQPWTQLRLSGHLKPLHYNL 194

  Fly   126 TIEPQLSGNFTFAGSVQIRIRVLEDCYNIT----MHAEELNISRSDASVHRVQNNGEPEGDGLRI 186
            .:...:. ||||:|.|.:.|.    |.|.|    :||       |..:|.:||...:.....:.:
Mouse   195 MLTAFME-NFTFSGEVNVEIA----CRNATRYVVLHA-------SRVAVEKVQVAEDRAFGAVPV 247

  Fly   187 HKQYLVGAKQFFVIELYDKLLKDVEYVVHLRFDGIIEDYLQGFYRSSYEVHNETRWVASTQFQAT 251
            ...:|....|..|:.|...|.....|.:.:.::.:||:.|.||:||||.:|.|.|::..|||..|
Mouse   248 AGFFLYPQTQVLVVVLNRTLDAQRHYNLKIIYNALIENELLGFFRSSYVIHGERRFLGVTQFSPT 312

  Fly   252 DARRAFPCFDEPALKANFTLHIARPRNMTTISNMPIVSS---NDHATMPSYVWDHFAESLPMSTY 313
            .||:||||||||..||.|.:.|.......::||||:.:|   .|     .:|.|||:::..||||
Mouse   313 HARKAFPCFDEPIYKATFKISIKHQATYLSLSNMPVETSVFEED-----GWVTDHFSQTPLMSTY 372

  Fly   314 LVAYAISDFTH----ISSGNFA-VWARADAIK--SAEYALSVGPRILTFLQDFFNVTFPLPKIDM 371
            .:|:||.:||:    ..||... ::||.|||:  |.:|||.:..|::.|.:|:|.|.:.|||:|:
Mouse   373 YLAWAICNFTYRETTTKSGVVVRLYARPDAIRRGSGDYALHITKRLIEFYEDYFKVPYSLPKLDL 437

  Fly   372 IALPEFQAGAMENWGLITFRETAMLYDPGVATANNKQRVASVVGHELAHQWFGNLVTPSWWSDIW 436
            :|:|:....|||||||..|.|..:|.||.|::.:....|..|:.||:.|||||:||||.||.|:|
Mouse   438 LAVPKHPYAAMENWGLSIFVEQRILLDPSVSSISYLLDVTMVIVHEICHQWFGDLVTPVWWEDVW 502

  Fly   437 LNEGFASYMEYLTADAVAPEWK-QLDQFVVNELQAVFQLDALSTSHKISHEVFNPQEISEIFDRI 500
            |.||||.|.|::..|.:.|.|. :..:|:.:.|..|..||.|::||.:|.||....:|..:||.|
Mouse   503 LKEGFAHYFEFVGTDYLYPAWNMEKQRFLTDVLHEVMLLDGLASSHPVSQEVLRATDIDRVFDWI 567

  Fly   501 SYAKGSTIIRMMAHFLTNPIFRRGLSKYLQEMAYNSATQDDLWHFLTVEAKSSGLLDDSRSVKEI 565
            :|.||:.:|||:|:|:.:.:|:|||..||....|.:|.::|||:.|:...:.:|   ...:::|:
Mouse   568 AYKKGAALIRMLANFMGHSVFQRGLQDYLTIHKYGNAARNDLWNTLSEALRRNG---KYVNIQEV 629

  Fly   566 MDTWTLQTGYPVVKVSRHPNSD-VIRLEQVRFVYTNTTR------EDESLLWYIPITFTTDSELN 623
            ||.||||.||||:.:..:..:: .|.:.|..|:|....:      ::.|.||.||:|....:. :
Mouse   630 MDQWTLQMGYPVITILGNTTAENRILITQQHFIYDIGAKTKALQLQNSSYLWQIPLTIVVGNR-S 693

  Fly   624 FANTRPTTWMPRTKLYELENRE---LSLAKWFIFNVQQTGYYRVNYDLENWMAITEHLMDVDNFE 685
            ..::....|:..    :.|:..   |....|.:.|:.||||:||||||.||..:.:.|  :.|.|
Mouse   694 HVSSEAIIWVSN----KSEHHRIAYLDRGSWILGNINQTGYFRVNYDLRNWRLLIDQL--IRNHE 752

  Fly   686 DIAPANRAQLIDDVMNLARGSYLSYETAMNLTRYLGHELGHVPWKAAISNFIFIDSMFVNSGDYD 750
            .::.:|||.||||..:|||..||.....:.:.|||..|...:||.||......:|.:.....:|:
Mouse   753 VLSVSNRAALIDDAFSLARAGYLPQNIPLEIIRYLSEEKDFLPWHAASRALYPLDKLLDRMENYN 817

  Fly   751 LLKNYLLKQLKKVYDQVGFKDSQDESEDILVKLK------RADILSMACHLGHQECIAEASRHFQ 809
            :...|:|||:...|.::|:  .::.....||:..      |.:::.:||..|::.|..:||....
Mouse   818 IFNEYILKQVATTYIKLGW--PRNNFNGSLVQASYQHEELRREVIMLACSFGNKHCHQQASTLIS 880

  Fly   810 NWMQTPNPDSNNPIVPNLRGVVYCSAIQYGTEYEWDFAFERFLKTNVPGEKDLLLNALGCSKEPW 874
            :|:.:    :.|.|..|:|.:|||:.:....|..|:|.:.:|..|....||.:||.||.||.:..
Mouse   881 DWISS----NRNRIPLNVRDIVYCTGVSLLDEDVWEFIWMKFHSTTAVSEKKILLEALTCSDDRN 941

  Fly   875 LLYRFLRRGISGQHIRKQDLFRVFAAVSTTVVGQNIAFDFLRNNWQEIKTYMGSQMSSIHTLFKF 939
            ||.|.|...::.:.:..||...|...|:....|:::|:.|.|:.|:.:.|..|..:.....|...
Mouse   942 LLSRLLNLSLNSEVVLDQDAIDVIIHVARNPHGRDLAWKFFRDKWKILNTRYGEALFMNSKLISG 1006

  Fly   940 ATKGFNSKFQLGEFENFVKDAHWDYDRPVQQIVEHIETSVDWMNKNYKSIVRWL 993
            .|:..|::.:|.|.:||:|...........:.||.:|.:|.|.......:.:||
Mouse  1007 VTEFLNTEGELKELKNFMKSYDGVASASFSRAVETVEANVRWKRFYQDELFQWL 1060

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
superdeath	NP_651674.3	M1_APN-Q_like	121..571	CDD:341064	176/464 (38%)
		ERAP1_C	651..976	CDD:463368	100/330 (30%)
Trhde	NP_666353.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	118..176		6/57 (11%)
		M1_APN-Q_like	190..635	CDD:341064	176/464 (38%)
		ERAP1_C	720..1044	CDD:463368	100/331 (30%)