Protein Alignment superdeath and Y42A5A.1

DIOPT Version :10

• Sequence 1: NP_651674.3
• Gene: superdeath / 43444
• FlyBaseID: FBgn0039640
• Length: 999
• Species: Drosophila melanogaster
• Sequence 2: NP_505820.1
• Gene: Y42A5A.1 / 179536
• WormBaseID: WBGene00012776
• Length: 1045
• Species: Caenorhabditis elegans
• Alignment Length: 1013
• Identity: 276/1013 - (27%)
• Similarity: 454/1013 - (44%)
• Gaps: 168/1013 - (16%)

  Fly    29 NAATPTTT---TTFSKGGRRYS-----------VSLTTAILLASFFICTLLA------------- 66
            :|:|.:||   ||.:...|:.|           |:::.:..|..||:...|.
 Worm    45 SASTTSTTAVATTVTSEQRQQSCCSARPLAIGVVAVSMSFALIYFFMIVPLTSSILPSQSSPILP 109

  Fly    67 --VGFIVYNFATCAELEPDSDEDVVCTSYHLRRLKAGHDDTPKY------DRDVRLPHSIRPLKY 123
              :..|....:|...:..:|.|.:..|            :.|.|      :..:::|....||.|
 Worm   110 SDISTIYQKSSTDFPIFTNSTELITTT------------EDPLYVHINNTNHRLQIPQIHIPLLY 162

  Fly   124 NITIE------PQL---SGNFTFAGSVQIRI------RVL---------EDCYNITMHAEELNIS 164
            .:.::      |.:   |.||:..|.|::..      |:|         .||    :..:|||.:
 Worm   163 EVELKLFVPWRPTISFGSDNFSVKGHVRVHFTSGGGSRILLHSDSKQHIGDC----VVRDELNRN 223

  Fly   165 RSDASVHRVQNNGEPEGDGLRIHKQYLVGAKQFFVIELYDKLLKDVEYVVHLRFDGIIE-DYLQG 228
            .:...|.|                ||    .|...:.|...::..:.|.:.:.|...|. :...|
 Worm   224 ITVKLVGR----------------QY----SQILDLNLETDMIHGMNYTLDVAFKSAINLNLAYG 268

  Fly   229 FYRSSYEVHNETRWVASTQFQATDARRAFPCFDEPALKANFTLHIARPRNMTTISNMPIVSSNDH 293
            .:.:.|...||||:|.:||.|.::||..|||.|.|.:||.|...|..|...|:|:||     .::
 Worm   269 LFAAPYTFENETRYVVATQLQISEARTVFPCIDVPDMKAQFDTVIIHPTGTTSIANM-----MEN 328

  Fly   294 ATMPSYVW--DHFAESLPMSTYLVAYAISDFTHIS--SGNFAVWAR--ADAIKSAEYAL---SVG 349
            :|.....|  ..|..:.||||||.|:::||:.::.  ||. .|.:|  .|..|..:..|   |:|
 Worm   329 STKVDGEWTTTTFHRTPPMSTYLFAFSVSDYPYLETFSGR-GVRSRVYCDPTKLVDAQLITKSIG 392

  Fly   350 PRILTFLQDFFNVTFPLPKIDMIALPEFQAGAMENWGLITFRETAMLYDPGVATANNKQRVASVV 414
            | :|.|.:|:|.:.:||.|:|::.:|.....|||||||||.|:|..||..|....:.|..|..:|
 Worm   393 P-VLDFYEDYFGIPYPLEKLDVVIVPALSVTAMENWGLITIRQTNGLYTEGRFAISQKHDVQEIV 456

  Fly   415 GHELAHQWFGNLVTPSWWSDIWLNEGFASYMEYLTADAVA-PEWKQLDQFVVNELQAV--FQLDA 476
            .|||||||||||||..||:|:|||||||:.:.....|.:. ..|:..|....::..|:  .|:|:
 Worm   457 AHELAHQWFGNLVTMKWWNDLWLNEGFATLISVRAVDFLENTTWRYEDSSAESQCVALRADQIDS 521

  Fly   477 LS-TSHKISHEVFNPQEISEIFDRISYAKGSTIIRMMAHFLTNPIFRRGLSKYLQEMAYNSATQD 540
            :| .|.|.:....:..||..  ..|.|.|.:.||||:...:...|||:||.::|....|.:|..:
 Worm   522 ISPVSGKKNSNFDSYMEIQG--KAIIYKKSAIIIRMIERLVEEDIFRQGLKRFLNTFLYKNADHE 584

  Fly   541 DLWHFLT-VEAKSSG--LLDDSRSVKEIMDTWTLQTGYPVVKVSRHPNSDVIRLEQVRFVYTNTT 602
            ||::.|. |...|:|  |...:.|:.::||||..|..:||:.|:|...| ::.|.|.:  |.:..
 Worm   585 DLFNVLVYVHDSSAGGHLRGQNFSLSDVMDTWIRQAHFPVIHVNRKEGS-LVTLRQEK--YEHVP 646

  Fly   603 R-EDESLLWYIPITFTTDSELNFANTRPTTWMPRTKLYELENRELSLAKWFIFNVQQTGYYRVNY 666
            | |.|..:|.||| |..|.   .:......|:..|     :.:...:....:.:..|..|.|:.|
 Worm   647 RDEPEKQVWKIPI-FYDDP---VSGKHKVFWLTDT-----QPKVFDMGGLLVVDPHQLTYMRLRY 702

  Fly   667 DLENWMAITEHLMDVDNFEDIAPANRAQLIDDVMNLARGSYLSYETAMNLTRYLGHELGHVPWK- 730
            |:|.:..||..||  |:|..|...:|::||||.:.:|....|:|:...|||.|:..|:.:.|::
 Worm   703 DMEMYSDITMALM--DDFTMIPTNSRSRLIDDTLAMAENGQLTYKVPFNLTMYMSREIAYRPFQT 765

  Fly   731 -AAISNFIFIDSMFVNSGDYDLLKNYLLKQLKKVYDQV---GFKDSQDESEDILVKLKRADILSM 791
             :|..:| |:..|:::.| :.:.|.||...:...:|:.   |...|.|.:.|:.  ..|..::..
 Worm   766 FSAYLDF-FLPRMYIHEG-WSIYKKYLELVVGIPFDKFNAEGLDVSFDHNTDLF--HTRQIVVFR 826

  Fly   792 ACHLGHQECIAEASRHFQNWMQTPNPDSN-------NPIVPNLRGVVYCSAIQYGTEYEWDFAFE 849
            ||.:.::.|:..|.:.|.......:.::.       |.|...||..||.:||..||:.::||.::
 Worm   827 ACGIEYEPCVRMAKQRFAELRVNCSGENQLLSGMECNKIPYYLRPHVYSAAINDGTQEDFDFLYK 891

  Fly   850 RFLKTNVPGEKDLLLNALGC-------SKEPWLLYRFLRRGISGQHIRKQDLFRVFAAVSTTVVG 907
            :::..:...|.|.:...| |       |...|       |.:.....|:..:.|. ...|..:..
 Worm   892 KWMIEHYMMEHDNIFTGL-CTTNIRENSDRAW-------RQVIKNGARENVMVRA-QLCSKKLSK 947

  Fly   908 QNIAFDFLRNNWQEIKTYMGSQMSSIHTLFKFATKGFN 945
            .|...|.|..:...:|.::.....|:..|.:...:..|
 Worm   948 NNFILDLLYEDKVYLKEFVDKDRKSLFALQQLLYRKIN 985

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
superdeath	NP_651674.3	M1_APN-Q_like	121..571	CDD:341064	159/490 (32%)
		ERAP1_C	651..976	CDD:463368	75/314 (24%)
Y42A5A.1	NP_505820.1	M1_APN-Q_like	160..618	CDD:341064	159/490 (32%)
		ERAP1_C	687..>939	CDD:463368	67/266 (25%)