Protein Alignment superdeath and LOC1278754

DIOPT Version :10

• Sequence 1: NP_651674.3
• Gene: superdeath / 43444
• FlyBaseID: FBgn0039640
• Length: 999
• Species: Drosophila melanogaster
• Sequence 2: XP_318379.6
• Gene: LOC1278754 / 1278754
• VectorBaseID: AGAMI1_000623
• Length: 880
• Species: Anopheles gambiae
• Alignment Length: 833
• Identity: 232/833 - (27%)
• Similarity: 375/833 - (45%)
• Gaps: 121/833 - (14%)

  Fly    88 VVCTSYHLRRLKAGHDDTPKYDRDVRLPHSIRPLKYNITIEPQLSG--NFTFAGSVQIRIRVLED 150
            |:|:.|.:        ..|....:.||.::..||.|::.:|....|  ::|:.|:|.|||.::.|
Mosquito     9 VLCSVYLV--------IVPVVTANGRLSNNTLPLHYDLHLEATGLGLHDYTYRGNVSIRIAIVSD 65

  Fly   151 CYNITMH-----AEELNISR---SDASVHRVQNNGEPEGDGLRIHKQYLVGAKQFFVIELYDKLL 207
            ...:.:|     .:.:.:.|   .:|..|::..: ||..:.|||..               |::|
Mosquito    66 TNEVVLHNVGNRLKSICLRRCRDGEAISHQLLES-EPASELLRIRT---------------DRIL 114

  Fly   208 K---DVEYVVHLRFDGIIEDYLQGFYRSSYE-VHNETRWVASTQFQATDARRAFPCFDEPALKAN 268
            :   |....:.:.|...:.:...||||:.|. .......||:|.||.:.||.||||||||..|..
Mosquito   115 RRADDQVITLTIVFHNTLGEDRMGFYRTQYRGAKRIPMAVATTHFQPSYARLAFPCFDEPGFKTT 179

  Fly   269 FTLHIARPRNMTTISNMPIVS----SNDHATMPSYVWDHFAESLPMSTYLVAYAISDFTHI---- 325
            |.:.|....:....||.||.:    .:.|..:      .|..:.||.||||.:.|::||.:
Mosquito   180 FQITIVANGSHLVASNAPIATVTWLQDGHKAV------RFERTPPMQTYLVTFLIANFTSVHTVS 238

  Fly   326 -SSGNFAVWARADAIKSAEYALSVGPRILTFLQDFFNVTFPLPKIDMIALPEFQAGAMENWGLIT 389
             |.....:.|.....||.:::|.....:|:.|:::...:..|.|:|.:|:|.| ..|||||||:.
Mosquito   239 PSGVEIGILAPPKDEKSLQFSLQAATTLLSSLEEYTGQSLGLQKLDHVAIPRF-GNAMENWGLVA 302

  Fly   390 FRETAMLYDPGVATANNKQRVASV--VGHELAHQWFGNLVTPSWWSDIWLNEGFASYMEYLTADA 452
            :.|..::..   |.|:..||..:|  :|||.|||.|||||.|:|||.:||:||||:|.|.|....
Mosquito   303 YDEQFLVLS---AKAHRLQRAQAVLTIGHETAHQLFGNLVGPAWWSYLWLSEGFATYFELLLGAD 364

  Fly   453 VAPEWKQLDQ-FVVNELQAVFQLDALSTSHKISHEVF--NPQEISEIFDRISYAKGSTIIRMMAH 514
            ..||...|:: |.|..:......||.. .|.::.|..  |..||..:||.|:|:|...|:||:..
Mosquito   365 AYPELLPLEESFAVRHMHPALMADAYE-QHPLTVEPLSANTPEIETLFDTITYSKAGCILRMINC 428

  Fly   515 FLTNPIFRRGLSKYLQEMAYNSATQDDLWHFLTVEAKSSGLLDDSRSVKEIMDTWTLQTGYPVVK 579
            .:....|:.|:..||::......|.:||:....|:.:.     |:.:|:::..:|..:.|||||.
Mosquito   429 SIGEEAFQAGVQNYLEQHRNGIVTPEDLYASFFVQQRK-----DTPTVEQMFRSWVDKPGYPVVT 488

  Fly   580 VSRHPNSDVIRLEQVRFVYTNTTREDESLLWYIPITFTTDSELNFANTRPTTWMPRTKLYELENR 644
            |.| .|...:|..|.|:.....|.:|.:..|:||||:.|:|.|.....:|..||..|....:...
Mosquito   489 VER-LNGSFVRFRQQRYHNQEVTIQDITSRWFIPITYYTNSSLGQYEYQPAFWMKETDQELVLQL 552

  Fly   645 ELSLAKWFIFNVQQTGYYRVNYDLENWMAITEHLMDVDNFEDIAPANRAQLIDDVMNLARGSYLS 709
            :::.....:.|.:|.|:|||.||...|.:|      |||...:....:|:||||...|||...:.
Mosquito   553 KMNTQDVLVVNPRQIGFYRVEYDERGWSSI------VDNLTTLPSIMQAKLIDDAFVLARAGLVG 611

  Fly   710 YETAMNLTRYLGHELGHVPWKAAIS--NFIFIDSMFVNSGDYDLLKNYLLKQLKKVYDQVGFKDS 772
            ||..:.:.:.|......|||..|::  |..::..: :.|.::|......:.::..:...||....
Mosquito   612 YELCLEMLQELATSPDPVPWLIAMAEENIGYLQRV-LQSAEFDRFLTGFVGEMFDLAGNVGRTLL 675

  Fly   773 QDESEDI-----------LVKLKR-ADILSMACHLGHQECIAEA---------SRHFQNWMQTPN 816
            |.::.|:           .::.|| :.|...||.....:.:.:|         .|.|......|.
Mosquito   676 QSQALDVAYDWWSRLAASFIESKRESSIRPRACLPTPVQEVVQALVSPDDHVRERLFVRLKCLPK 740

  Fly   817 PDSNNPIVPNLRGVVYCSAIQYGTEYEWDFAFERFLKTNV--PGEKDLLLNAL 867
             .||.|.|..|                   |.||....|:  ||:...:|.:|
Mosquito   741 -QSNEPSVLLL-------------------ALERIRAANLLTPGKLFAVLESL 773

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
superdeath	NP_651674.3	M1_APN-Q_like	121..571	CDD:341064	143/477 (30%)
		ERAP1_C	651..976	CDD:463368	57/242 (24%)
LOC1278754	XP_318379.6	None