Protein Alignment superdeath and erap1

DIOPT Version :10

• Sequence 1: NP_651674.3
• Gene: superdeath / 43444
• FlyBaseID: FBgn0039640
• Length: 999
• Species: Drosophila melanogaster
• Sequence 2: XP_002933475.2
• Gene: erap1 / 100496768
• XenbaseID: XB-GENE-983344
• Length: 932
• Species: Xenopus tropicalis
• Alignment Length: 961
• Identity: 322/961 - (33%)
• Similarity: 516/961 - (53%)
• Gaps: 102/961 - (10%)

  Fly    88 VVCTSYHLRRLKAGH---DDTPKYD-RDVRLPHSIRPLKYNITIEPQLSGNFTFAGSVQIRIRVL 148
            ::|.|:.::...|..   |:...:. :::|||....||.|::.|.|.|: ..||:|..::.:.|.
 Frog    23 LMCISFSIQPALAASKALDNAEMFPWKNLRLPTFAAPLHYDLLIHPNLT-TLTFSGLTKVTVTVT 86

  Fly   149 EDCYNITMHAEELNISRSDASVHRVQNNGEPEGDGLRIHKQYLVGAKQFFVIELYDKLLKDVEYV 213
            :....:.:|::.|.|:::  ::.| :...:|....|.:.:.   ...:...:...|.|:....|.
 Frog    87 QKTSFLVLHSKHLEITKT--TIKR-KLGKDPVLQDLLLREH---PVNEQIALLAADPLIPGENYT 145

  Fly   214 VHLRFDGIIEDYLQGFYRSSYEVHN-ETRWVASTQFQATDARRAFPCFDEPALKANFTLHIARPR 277
            :::.::..:....:|||:|:|:..: |.|.:|||||:.|.||.|||||||||.||:|::.|.|..
 Frog   146 IYIEYNANLSKNFRGFYKSTYKTKDGEVRVLASTQFEPTAARTAFPCFDEPAFKASFSIQIRREP 210

  Fly   278 NMTTISNMPIVSSNDHATMPSYVWDHFAESLPMSTYLVAYAISDFTHIS-----SGNFAVWARAD 337
            ....:||||:|.:.:..  ...:.||||.|:.|||||||:.:|||..||     ....:|:|..:
 Frog   211 KHHAVSNMPVVKTVNIG--GGLLEDHFAASVKMSTYLVAFIVSDFKSISQVTNHGVRISVYATPE 273

  Fly   338 AIKSAEYALSVGPRILTFLQDFFNVTFPLPKIDMIALPEFQAGAMENWGLITFRETAMLYDPGVA 402
            .|..|||||....::|.|.:|:||:::||||.|:.|:|:||:||||||||.|:||:|:|:||..:
 Frog   274 KIDQAEYALKAAVKLLDFYEDYFNISYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLHDPKTS 338

  Fly   403 TANNKQRVASVVGHELAHQWFGNLVTPSWWSDIWLNEGFASYMEYLTADAVAPEWKQLDQFVVNE 467
            ||::|..|..::.|||||||||||||..||:|:|||||||.:|||::.....|| .|::.:.:::
 Frog   339 TASHKLWVTMIIAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEYVSVRVTYPE-LQVEDYFLDK 402

  Fly   468 LQAVFQLDALSTSHKISHEVFNPQEISEIFDRISYAKGSTIIRMMAHFLTNPIFRRGLSKYLQEM 532
            ......:|:|::||.:|..|.||:||.|:||.:||.||:.|:.|:..::....|..|:..||:..
 Frog   403 CFRAMDVDSLNSSHAVSTPVENPEEIQEMFDEVSYDKGACILNMLMDYMGAESFEAGIVDYLRRY 467

  Fly   533 AYNSATQDDLWHFLT----VEAKSSGLLDDSR-----------SVKEIMDTWTLQTGYPVVKVSR 582
            :|.:|..:|||:.:|    .:..:||....:|           .||.:|:|||||.|:|:|.|:
 Frog   468 SYRNARNEDLWNSMTDVCPSDETNSGYCTKTRQTSHWSEGEIIDVKSMMNTWTLQKGFPLVTVT- 531

  Fly   583 HPNSDVIRLEQVRFVYTNTTREDESLLWYIPITFTTDSELNFANT-RPTTWMPRTKLYELENREL 646
             .....:.|.|..::..:|..|...|||:||:|:.|..    :|| :....|.:|.:..|...
 Frog   532 -VKGKYVYLHQEHYLKGSTDTEASGLLWHIPLTYITSK----SNTVQRFLLMSKTDVLVLAEE-- 589

  Fly   647 SLAKWFIFNVQQTGYYRVNYDLENWMAITEHLMDVDNFEDIAPANRAQLIDDVMNLARGSYLSYE 711
              .:|..|||...|||.|:|:.|.|.|:.:.|.  :|...|:..:||.||:....|.....|..:
 Frog   590 --VEWIKFNVGMNGYYIVHYEGEGWDALIKLLQ--ENHTAISSNDRANLINSAFQLVSIGRLPID 650

  Fly   712 TAMNLTRYLGHELGHVPWKAAISNFIFI-------DSMFVNSGDYDLLKNYLLKQLKKVYDQVGF 769
            .|::|:.||.:|...:|....:...|.|       |...|.|    .:|.|:|..|:|:.|...:
 Frog   651 KALSLSLYLKNEDKIMPVFQGMDELIPIYKLMEKRDMQEVES----QMKKYILNLLRKLIDAQSW 711

  Fly   770 KDSQDESEDILVKLKRADILSMACHLGHQECIAEASRHFQNWMQTPNPDSNNPI-VP-NLRGVVY 832
            .|....||.:|    |:.:|..||...:|.|:..|.::|:.|.     :||..| :| ::...||
 Frog   712 TDEGSVSERML----RSSLLLFACVRQYQPCVQRAEQYFKRWQ-----ESNGTISLPRDVASAVY 767

  Fly   833 CSAIQYGTEYEWDFAFERFLKTNVPG-EKDLLLNALGCS----KEPWLLYRFLRRGISGQHIRKQ 892
            ....|  |...|||.||:: ||.:.| ||:.:..||..:    |..||    :..|:.|.|:|.|
 Frog   768 AVGAQ--TPEGWDFLFEKY-KTTLSGSEKNQIELALAITSLKHKLQWL----MEEGMKGDHVRTQ 825

  Fly   893 DLFRVFAAVSTTVVGQNIAFDFLRNNWQEI--KTYMGSQMSSIHTLFKFATKGFNSKFQLGEFEN 955
            ||..:...||...||..::::||:|||..:  |..:||:  ::..:....||.:::|..|.|...
 Frog   826 DLPHIVLYVSRNPVGYPLSWEFLKNNWGNLVQKFELGSR--TVGDMVVGITKQYSTKEWLEEVTG 888

  Fly   956 FVKDAHWDYD---------RPVQQIVEHIETSVDWMNKNYKSIVRWLENEA 997
            |       :|         |.|||..|.||.::.||:||...:..||||.:
 Frog   889 F-------FDSLKEMGSQLRCVQQARETIEENIRWMDKNLDLVKSWLENNS 932

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
superdeath	NP_651674.3	M1_APN-Q_like	121..571	CDD:341064	176/470 (37%)
		ERAP1_C	651..976	CDD:463368	105/349 (30%)
erap1	XP_002933475.2	M1_APN-Q_like	60..521	CDD:341064	176/470 (37%)
		ERAP1_C	592..911	CDD:463368	105/349 (30%)