Protein Alignment Bicra and bicral

DIOPT Version :10

• Sequence 1: NP_001263051.1
• Gene: Bicra / 43435
• FlyBaseID: FBgn0039633
• Length: 3003
• Species: Drosophila melanogaster
• Sequence 2: XP_005156436.1
• Gene: bicral / 559084
• ZFINID: ZDB-GENE-100716-3
• Length: 856
• Species: Danio rerio
• Alignment Length: 842
• Identity: 175/842 - (20%)
• Similarity: 285/842 - (33%)
• Gaps: 256/842 - (30%)

  Fly  1669 MSASIQPF--------QTTSGTKLVGVTVPMQ-QQQPTGTAAILQQQQQQRTSFSLTATTVATPA 1724
            :|:|: ||        .:..|..|.|...|.. .|:....|.|.:|...|........:.:.|..
Zfish   111 LSSSL-PFIEDDLDSETSADGVDLGGEDQPFDILQKSLLEADITEQTLAQEALLDSQPSLIPTAT 174

  Fly  1725 PMPSPTVASGVSQLQMQQLPSQQAQQQLQPQQQQQLHAPKQQQPQPN--------------TVSR 1775
            ..|...|:.|.:.:....:.:..||.|...||..||       |.||              :.|.
Zfish   175 AFPQQLVSGGFAGVAGPGVVAPLAQPQAFIQQVPQL-------PLPNGPAGHIQVVGSFNGSASS 232

  Fly  1776 VQTIQLTPQMQQIFK------------------QVQMQIQFLTIKLQN---------KSTFLPVS 1813
            :.||....|.|.:.:                  ||.|.....||.:||         ::...|:.
Zfish   233 MMTINSLEQPQILLRQSGNNSGQGTMFAPSTPNQVSMSFNKGTIPVQNIIIQRGPTQQTLVRPIQ 297

  Fly  1814 PE-IDSATIAAYNKPMTDAEINLALQRLFAEQHRILASGKEVPTPEGMLPTANGTGGFSLMPQPV 1877
            |: :.:.....||..      |:.:|........:::|..          ||.|:      |||.
Zfish   298 PKPLQTGGQTVYNIS------NIGIQPSTTTAGNLVSSAY----------TATGS------PQPA 340

  Fly  1878 QQQQ---------------QQQQQQLQSTVPE------------PLKTI-----VPANVVQPNNH 1910
            ||.:               ||.|.|.||.:|:            |..|:     |...|:|.|
Zfish   341 QQVKVVNPASSIVMHSPLGQQAQTQSQSNLPQGQFLLPSSISLTPGTTVHGFQAVNGQVLQGN-- 403

  Fly  1911 SSTPAGAATSGATTAANIQQNITQRIHIYPMQHQQQQQQQQQQQQQQPQHQQQQPQHQLQQTGAK 1975
              |..|..:|.:||..:|..|....:.:...|:.....|....|.              ..:|.:
Zfish   404 --TQVGDPSSMSTTTYSILTNQNTTVQLIAGQNFSAGGQLIVNQG--------------LVSGGQ 452

  Fly  1976 PKQAQPKPPPQQEQQSQLQIKPKEPANRSKVTSQQLQQNPQPPNGT-----INMLPQKVSMMPVV 2035
            ..||.|.|..|..|:         ||..:||.:.....:|.|...|     :.|:...| ..|.|
Zfish   453 IGQASPTPVVQVSQR---------PAAAAKVWTSSASPSPTPVQATQTSSHLTMISSGV-QGPQV 507

  Fly  2036 QQQQQQQPQQHQQQPMLNKSGPPPLIFASSTN-----MLSNSNSNNLHNSNSAMQVNNMLPLPPL 2095
            .||....|.||...|:...        ||:|:     .:|.:............|:.|:|
Zfish   508 CQQLSVNPGQHLLMPVGQN--------ASATSGFQEFQVSLNQDTTAATQRGQTQLVNLL----- 559

  Fly  2096 QPQQQPQPQLQQPPTPILPPVAPTMAMGVAPGPMGNLVPSLPTIPSLPLYMPSKMDEMPTQKPKI 2160
                         .|.:|.|:.|..             ..||..|..|          .||  ::
Zfish   560 -------------GTKVLKPLTPAS-------------QELPLTPKRP----------ATQ--QL 586

  Fly  2161 ARLSLFVRQLEVDQESCLKPDYVKPFRTKDEAVKRLIRYHCMHENDVELPSDE-----DEEFEST 2220
            .|..|.::||..|....|..|.. ||.:.::.:.||:.||....:.   |.||     |||||:.
Zfish   587 TRGELVLQQLRQDHSRVLSSDRT-PFSSLNDVIDRLLPYHVFQGSP---PQDEDFAKVDEEFEAV 647

  Fly  2221 ALEFQDKFRQLNGKFQEILMQESTLPHRTSELLQMQQLMIDDLKGEINEIR-------------- 2271
            |.:...:.:.:..|::.:||.|:.....:||::.:.:....:.:|.:.:.:
Zfish   648 ATQVLSRTQAMVNKYRRLLMVEAERSSPSSEMVMIDRTFNQEERGNLTQDKRMVLVDPDSFLEEF 712

  Fly  2272 --------TAEKELEQQLKEEQTSEKSTAESDVLS-------------EAKVKEEIKQEPIDKSA 2315
                    .:.:.|.....|::.|:..|:.|..:|             |...:.|.:|:.:::..
Zfish   713 CCGPKRKIPSPEVLTPASHEDKPSKMETSPSHSISHTGRDGQSMNSHTETTYRTESQQQEMEEHR 777

  Fly  2316 Q-PDGVVDKFDLLKNSADVNKAF-SKSQPQQTTTVKQEESNESGEPSVNGSVKSEGHDKESS 2375
            : |...:  .||.|.::  |..| ||||..|..|    ..|:|.:.|..|...:.||:::.|
Zfish   778 RTPIKCI--LDLKKKTS--NSVFGSKSQHAQYPT----SPNQSQQSSAQGYPSNPGHEQKLS 831

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bicra	NP_001263051.1	PHA03247	<753..1222	CDD:223021
		GLTSCR1	2173..2271	CDD:464589	25/102 (25%)
		SCP-1	<2212..2476	CDD:114219	43/206 (21%)
bicral	XP_005156436.1	GLTSCR1	599..699	CDD:464589	25/103 (24%)