Protein Alignment Sirt7 and sirt6

DIOPT Version :10

• Sequence 1: NP_651664.2
• Gene: Sirt7 / 43433
• FlyBaseID: FBgn0039631
• Length: 771
• Species: Drosophila melanogaster
• Sequence 2: NP_989353.1
• Gene: sirt6 / 394980
• XenbaseID: XB-GENE-5929105
• Length: 331
• Species: Xenopus tropicalis
• Alignment Length: 368
• Identity: 123/368 - (33%)
• Similarity: 177/368 - (48%)
• Gaps: 97/368 - (26%)

  Fly   101 EREDAPHVIEAKVEQLANIISQAKHLVCYTGAGISTAALIPDYRGSQGIWTLLQKGQDIGEHDLS 165
            |..|.|..:..||.:||::|.::.::|.:|||||||:..|||:||..|:|||.:||.: .:.|::
 Frog    22 EAFDPPDELCRKVVELADMIRKSSYVVFHTGAGISTSCGIPDFRGPNGVWTLEEKGVN-PKFDIT 85

  Fly   166 --SANPTYTHMALYELHRRRLLHHVVSQNCDGLHLRSGLPRNSLSEIHGNMYVEVCKNCRPNSVY 228
              ||.|:.|||||.:|.|..:|..:||||.||||:|||.||..|:|:||||:||.|..|.
 Frog    86 FESACPSPTHMALLQLQRVGILKFLVSQNVDGLHVRSGFPREQLAELHGNMFVEECSKCS----- 145

  Fly   229 WRQFDTTEMTARYCHK-THRLC--------HRCSEPLYDTIVHFGERGNVKWPLNWAG------- 277
             :|:...::......| |.|||        ..|...|.|||            |:|..
 Frog   146 -KQYVRDQVVGTMGLKPTGRLCDVPKVRGLRACRGKLKDTI------------LDWEDSLPDRDL 197

  Fly   278 --ATANAQRADVILCLGSSLKVLKKYTWLWQMDRPA--------RQRAKICVVNLQWTPKDAIAS 332
              |....::||:.:.||:||::           ||:        |:..|:.:||||.|..|..|.
 Frog   198 NLADEACRKADLSITLGTSLQI-----------RPSGNLPLLTKRKGGKLVIVNLQPTKHDKHAD 251

  Fly   333 IKINGKCDQVMAQLMHLLHIPVPVYTKEKDPIFAHASLLMPEELHTLTQPLLKNADEEEAFTTTT 397
            ::|:|..|:||.|||.||...:||:|.            ||    |.|:|...|..||..|
 Frog   252 LRIHGYVDEVMTQLMELLGHKIPVWTG------------MP----TKTEPTNGNYKEENHF---- 296

  Fly   398 EETQDSTISSESCSFNYSDLPIGKGPRIRTPIKNGRRVKTNLE 440
                            |:|..:|..|..:   :.|.:.:.|||
 Frog   297 ----------------YNDSVLGANPNQK---REGCKEEPNLE 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt7	NP_651664.2	SIRT7	124..338	CDD:238701	86/241 (36%)
sirt6	NP_989353.1	SIRT7	45..257	CDD:238701	86/241 (36%)