Protein Alignment Slu7 and SLU7

DIOPT Version :10

• Sequence 1: NP_651659.2
• Gene: Slu7 / 43427
• FlyBaseID: FBgn0039626
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001351446.1
• Gene: SLU7 / 10569
• HGNCID: 16939
• Length: 601
• Species: Homo sapiens
• Alignment Length: 596
• Identity: 305/596 - (51%)
• Similarity: 385/596 - (64%)
• Gaps: 61/596 - (10%)

  Fly    15 LSKHDQDAEEEPKKKSREDWRKAKELEEARKAGTAPAAVDEEGRDINPHIPQYISNAPWYYG-SA 78
            ||...:.:.|||||.:||||||.|||||.||.|.|||.|||||:|||||||||||:.|||.. |.
Human    29 LSGSKEMSLEEPKKMTREDWRKKKELEEQRKLGNAPAEVDEEGKDINPHIPQYISSVPWYIDPSK 93

  Fly    79 GPTLKHQRPQHEDEQ-----GQLDKRAPKGLNTARIITKFRKGACENCGAVTHKRKDCLERPRKV 138
            .|||||||||.|.::     |:..||   |:....||||:||||||||||:|||:|||.||||:|
Human    94 RPTLKHQRPQPEKQKQFSSSGEWYKR---GVKENSIITKYRKGACENCGAMTHKKKDCFERPRRV 155

  Fly   139 QAKYAESIVVHDEHLVNEAAVNYDEKRDRWSSYDPANHREIIEEYEKVEEAKRQLKAEKLK---- 199
            .||:..:.:..|||:..:...:||.|||||:.|:|..|.:|:|||.||:.|||.|||:||:
Human   156 GAKFTGTNIAPDEHVQPQLMFDYDGKRDRWNGYNPEEHMKIVEEYAKVDLAKRTLKAQKLQEELA 220

  Fly   200 --------NDPDAEISDEEGN-------------EDKYVDEVDMPGTKVDSKQRITVRNLRIRED 243
                    |.|..:..:||.|             ||||.|::||||...|||:||||||||||||
Human   221 SGKLVEQANSPKHQWGEEEPNSQMEKDHNSEDEDEDKYADDIDMPGQNFDSKRRITVRNLRIRED 285

  Fly   244 TAKYLRNLDPNSAYYDPKTRSMRDNP--NPAVPEEEAEFAGENFVRFSGDTTAQATAQLFAWEAH 306
            .|||||||||||||||||||:||:||  |.....:|..:||:||||::|||.:.|..|||||||:
Human   286 IAKYLRNLDPNSAYYDPKTRAMRENPYANAGKNPDEVSYAGDNFVRYTGDTISMAQTQLFAWEAY 350

  Fly   307 GKGVDVHLLAEPTKLELLQKEYEQKKEQFKSSTKTHIVEKYGGEEHLQVPPKSLLLAQTEEYIEY 371
            .||.:|||.|:|||||||.|.::.|||.||...|..|:|||||:|||..||..|||||||:|:||
Human   351 DKGSEVHLQADPTKLELLYKSFKVKKEDFKEQQKESILEKYGGQEHLDAPPAELLLAQTEDYVEY 415

  Fly   372 SRSGKVIKGVEKPKARSIYEEDVYINNHTTVWGSFWNAGRWGYKCCKSFIKNSYCVGMQEPEGYS 436
            ||.|.||||.|:..|.|.|||||.|:|||.:|||:|..||||||||.||.|.|||.|....|
Human   416 SRHGTVIKGQERAVACSKYEEDVKIHNHTHIWGSYWKEGRWGYKCCHSFFKYSYCTGEAGKE--- 477

  Fly   437 EHHSTSSTAAATTEPAAQSQFKVPEVPPERPTSEVDSASSSEPSSSEEEEVKPEKKKTKKKSKK- 500
               ..:|......|...:...|.|:...|                ..:|::|.||||.|||.||
Human   478 ---IVNSEECIINEITGEESVKKPQTLME----------------LHQEKLKEEKKKKKKKKKKH 523

  Fly   501 REKKKKAKEQRKQKGKNKETKDKDKTKEKDIPE--ELDDRKRAYNSMYDVKAPTEDEIEEWKKKR 563
            |:....:.::.|:..|.|:..:.::.:...:.|  ::|:|||.|||||:.:.|||:|:|.::.||
Human   524 RKSSSDSDDEEKKHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKR 588

  Fly   564 PRAEDPMLQFM 574
            .|.:|||..|:
Human   589 QRPDDPMASFL 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slu7	NP_651659.2	Slu7	160..405	CDD:463326	156/271 (58%)
SLU7	NP_001351446.1	Slu7	176..449	CDD:463326	156/272 (57%)