Protein Alignment AstA-R2 and ackr3

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001025605.1
• Gene: ackr3 / 594993
• XenbaseID: XB-GENE-939861
• Length: 361
• Species: Xenopus tropicalis
• Alignment Length: 349
• Identity: 89/349 - (25%)
• Similarity: 151/349 - (43%)
• Gaps: 50/349 - (14%)

  Fly     6 MLANISLNATRNEENITSFFTDEEWLAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVFNNNMR 70
            :|.::|...|.|:.            |:..||..:..|.|    :.|...|.:||.:   |...:
 Frog    23 ILESLSCPNTLNKS------------ALLYTLAIVYIFIF----VMGLLANSMVIWL---NLQAK 68

  Fly    71 ST---TNLMIVNLAAADLMFVILCIPFTATDYMVY-YWPYGRFWCRSVQYLIVVTAFASIYTLVL 131
            :|   |:|.|.|||.|||. |:|.:|......:.: .||.|...|:....:..:..::||:.|..
 Frog    69 TTGYETHLYIFNLAIADLC-VLLTLPVWVVSLVQHNQWPMGEMTCKITHLVFSINLYSSIFFLTC 132

  Fly   132 MSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTF 196
            ||:||:|.|.....:...|.:.|..:..|.:|:|..|||:|..:....|  .....|.||....:
 Frog   133 MSVDRYLCVSLNGTAGQRRRKIIRRLVCVLVWLVAFVVSLPDTYYLKTV--SSPVTNETYCRSMY 195

  Fly   197 TTNDF----LGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRMSKESQRGRKRVT-R 256
            ....|    ||   .::...:..:::|..||:..|   .:..|...:....|.:.:|   |:: |
 Frog   196 PEETFKEWLLG---MEIVSIMLGFVIPFPIIAIFY---CLLAWTLSSSSSSSGDQER---RISGR 251

  Fly   257 LVVVVVIAFASLWLPVQLILLLKSLDVIE-------TNTLTKLVIQVTAQTLAYSSSCINPLLYA 314
            |:|..|:.|...|||...:::|..:..::       .:......:.:| |..:....||||:||:
 Frog   252 LIVSYVVVFMVCWLPYHAMVILDVMSFLQLLPFSCFLDNFLYAALHIT-QCYSLLHCCINPILYS 315

  Fly   315 FLSENFRKAFYKAVNCSSRYQNYT 338
            |:..|:|....||.  ..||.:.|
 Frog   316 FIHRNYRYEIMKAF--IFRYSSKT 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	77/300 (26%)
		TM helix 1	40..66	CDD:320224	6/25 (24%)
		TM helix 2	73..99	CDD:320224	12/25 (48%)
		TM helix 3	111..141	CDD:320224	9/29 (31%)
		TM helix 4	153..173	CDD:320224	7/19 (37%)
		TM helix 5	204..233	CDD:320224	4/28 (14%)
		TM helix 6	249..279	CDD:320224	10/30 (33%)
		TM helix 7	292..317	CDD:320224	9/24 (38%)
ackr3	NP_001025605.1	7tmA_ACKR3_CXCR7	40..325	CDD:320118	79/304 (26%)
		TM helix 1	41..67	CDD:320118	9/32 (28%)
		TM helix 2	74..98	CDD:320118	12/24 (50%)
		TM helix 3	112..142	CDD:320118	9/29 (31%)
		TM helix 4	155..176	CDD:320118	8/20 (40%)
		TM helix 5	204..231	CDD:320118	6/32 (19%)
		TM helix 6	244..274	CDD:320118	10/32 (31%)
		TM helix 7	293..318	CDD:320118	9/25 (36%)