Protein Alignment AstA-R2 and Uts2r

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_663415.1
• Gene: Uts2r / 217369
• MGIID: 2183450
• Length: 385
• Species: Mus musculus
• Alignment Length: 348
• Identity: 97/348 - (27%)
• Similarity: 166/348 - (47%)
• Gaps: 53/348 - (15%)

  Fly     1 MENTT--MLA-------------NISLNATRNEENITSFFTDEEWLAINGTLPWIVGFFFGVIAI 50
            :|:|:  |||             |:|.|::.......|...|   |...|    ::|.....:.:
Mouse     5 LESTSFPMLAVSRSTASELPGGFNVSHNSSWTGPTDPSSLQD---LVATG----VIGAVLSTMGV 62

  Fly    51 TGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQ 115
            .|..||:..::|:.......::..:.:||||.|||:: :|.|||....|:...|.:|...||.:.
Mouse    63 VGVVGNVYTLVVMCRFLRASASMYVYVVNLALADLLY-LLSIPFIVATYVTKDWHFGDVGCRVLF 126

  Fly   116 YLIVVTAFASIYTLVLMSIDRFLAVVHPI----RSRMMRTENITLIAIVTLWIVVLVVSVPVAFT 176
            .|..:|..|||:||.:||.:|:.||:.|:    ||:..|    .|:|:.| |::.|::::|:...
Mouse   127 SLDFLTMHASIFTLTIMSSERYAAVLRPLDTVQRSKGYR----KLLALGT-WLLALLLTLPMMLA 186

  Fly   177 HDVVVDYDAKKNITYGMCTFTTNDFLGP---RTYQVTFFISSYLLPLMIISGLYMRMIMRLW--R 236
            ..:|      :..:..:|.    ...||   |||....|.:|.:.|.::|..||:|:....|  :
Mouse   187 IRLV------RRGSKSLCL----PAWGPRAHRTYLTLLFGTSIVGPGLVIGLLYIRLARAYWLSQ 241

  Fly   237 QGTGVRMSKESQR-GRKRVTRLVVVVVIAFASLWLPVQLILLLKSL-DVIETNTLTKLVIQVTAQ 299
            |.:    .|:::| ...||..|::.:|:.|.:.:||..|..||... ..:.....|..:|.....
Mouse   242 QAS----FKQTRRLPNPRVLYLILGIVLLFWACFLPFWLWQLLAQYHQAMPLTPETARIINYLTA 302

  Fly   300 TLAYSSSCINPLLYAFLSENFRK 322
            .|.|.:|||||.||..|::|:|:
Mouse   303 CLTYGNSCINPFLYTLLTKNYRE 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	85/295 (29%)
		TM helix 1	40..66	CDD:320224	5/25 (20%)
		TM helix 2	73..99	CDD:320224	11/25 (44%)
		TM helix 3	111..141	CDD:320224	13/29 (45%)
		TM helix 4	153..173	CDD:320224	5/19 (26%)
		TM helix 5	204..233	CDD:320224	11/31 (35%)
		TM helix 6	249..279	CDD:320224	10/30 (33%)
		TM helix 7	292..317	CDD:320224	10/24 (42%)
Uts2r	NP_663415.1	7tmA_UII-R	53..327	CDD:320130	85/293 (29%)
		TM helix 1	53..78	CDD:320130	5/24 (21%)
		TM helix 2	85..109	CDD:320130	11/24 (46%)
		TM helix 3	122..152	CDD:320130	13/29 (45%)
		TM helix 4	164..185	CDD:320130	7/25 (28%)
		TM helix 5	207..236	CDD:320130	10/28 (36%)
		TM helix 6	251..281	CDD:320130	9/29 (31%)
		TM helix 7	295..320	CDD:320130	10/24 (42%)