DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpS22 and Mrps22

DIOPT Version :9

Sequence 1:	NP_524537.1	Gene:	mRpS22 / 43345	FlyBaseID:	FBgn0039555	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_001070998.1	Gene:	Mrps22 / 683519	RGDID:	1585674	Length:	359	Species:	Rattus norvegicus

Alignment Length:	352	Identity:	104/352 - (29%)
Similarity:	178/352 - (50%)	Gaps:	54/352 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 PTKPAALQYERD----PQPLFTDAETQRLLQSMTQLNLDKVYRKRTVPDNSSETKFMSNEQLDNE 87
            |.:|.:.:.|..    .:|.|.|.|.|.:|..||.|:|.|.::....|......|.|:..||: |
  Rat    49 PRRPFSSEAESGSSEVKKPTFMDEEVQSILTKMTGLDLQKTFKPAVQPLKPPTYKLMTQAQLE-E 112

  Fly    88 FQNLVVRAQQI-LQMPPIVQIKKDVERVIAKDTALKDFANSKFVFTDITFGRRQSERKVIVRDMD 151
            ...|.|.|.:| |:|||:::.:|.:..|:|:|..|:....:|:|||||::.....||.::||:..
  Rat   113 ATRLAVEAAKIRLKMPPVLEERKPINDVLAEDKILEGTETNKYVFTDISYNIPHRERFIVVREPS 177

  Fly   152 GTLAYATLDTTKRMNQLYFPLEGRQSYTPRMFALEELLAKCLAEHKYEFILDRLLVQYEPHEPEF 216
            |||..|:.:...|:.|:|||.|||:...|.:|. :|.|....::.::..:|:..:.|:||...|:
  Rat   178 GTLRKASWEERDRVIQIYFPKEGRRVLPPVIFK-DENLKTMYSQDRHADVLNLCVAQFEPDSTEY 241

  Fly   217 HNISARVFEHLNESKEFDLLRSTRHFGPMAFFYAWHRCIDDLLYDMIRRDYLHNAVELIALSYKL 281
            ..:..:.:|.::...::::||||||||.||::...::.||.||.|.|:||.:.:|..|:.|.:.|
  Rat   242 IKVHHQTYEDIDRHGKYEILRSTRHFGGMAWYLVNNKKIDGLLIDQIQRDLVDDATSLVQLYHML 306

  Fly   282 HNIPVEYQATLTELGKLHATPAESALAELRSVFRRHDNKQNIEQEIHTAIGKTEHDFAADEISLK 346
            |                   |...:..|.:            ||             ||:.::|
  Rat   307 H-------------------PEGQSAQEAK------------EQ-------------AAEGVNL- 326

  Fly   347 FIEQYIASEHALKKVQLELAVQTLKEV 373
             |:.:..:| |.:...:|||:||.:|:
  Rat   327 -IKVFAKTE-AQRGAYIELALQTYQEI 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpS22	NP_524537.1	MRP-S22	41..282	CDD:287247	83/241 (34%)
Mrps22	NP_001070998.1	MRP-S22	67..307	CDD:287247	83/241 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338205
Domainoid	1	1.000	153	1.000	Domainoid score	I4203
eggNOG	1	0.900	-	-		E1_KOG3890
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H57030
Inparanoid	1	1.050	154	1.000	Inparanoid score	I4238
OMA	1	1.010	-	-		QHG48815
OrthoDB	1	1.010	-	-		D363634at33208
OrthoFinder	1	1.000	-	-		FOG0007406
OrthoInspector	1	1.000	-	-		oto96181
orthoMCL	1	0.900	-	-		OOG6_107905
Panther	1	1.100	-	-	LDO	PTHR13071
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5531
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810