DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpS22 and Mrps22

DIOPT Version :9

Sequence 1:	NP_524537.1	Gene:	mRpS22 / 43345	FlyBaseID:	FBgn0039555	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_079761.1	Gene:	Mrps22 / 64655	MGIID:	1928137	Length:	359	Species:	Mus musculus

Alignment Length:	335	Identity:	102/335 - (30%)
Similarity:	172/335 - (51%)	Gaps:	50/335 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 QPLFTDAETQRLLQSMTQLNLDKVYRKRTVPDNSSETKFMSNEQLDNEFQNLVVRAQQI-LQMPP 103
            :|.|.|.|.||:|..:|.|:|.|.:|....|......|.|:..||: |...|.|.|.:: |:|||
Mouse    66 KPAFMDEEVQRILTKITGLDLQKTFRPAIQPLKPPTYKLMTQAQLE-EATRLAVEAAKVRLKMPP 129

  Fly   104 IVQIKKDVERVIAKDTALKDFANSKFVFTDITFGRRQSERKVIVRDMDGTLAYATLDTTKRMNQL 168
            :::.:|.:..|:|:|..|:....:|:|||||::.....||.::||:..|||..|:.:...|:.|:
Mouse   130 VLEERKPINDVLAEDKILEGTETNKYVFTDISYNIPHRERFIVVREPSGTLRKASWEERDRVIQI 194

  Fly   169 YFPLEGRQSYTPRMFALEELLAKCLAEHKYEFILDRLLVQYEPHEPEFHNISARVFEHLNESKEF 233
            |||.|||:...|.:|. :|.|....::.::..:|:..:.|:||...|:..:..:.:|.::...::
Mouse   195 YFPKEGRRVLPPVIFK-DENLKTMYSQDRHADVLNLCVAQFEPDSAEYIKVHHQTYEDIDRHGKY 258

  Fly   234 DLLRSTRHFGPMAFFYAWHRCIDDLLYDMIRRDYLHNAVELIALSYKLHNIPVEYQATLTELGKL 298
            :|||||||||.||:::...:.||.||.|.|:||.:.:|..|:.|.:.||
Mouse   259 ELLRSTRHFGGMAWYFVNKKKIDGLLIDQIQRDLVDDATSLVQLYHMLH---------------- 307

  Fly   299 HATPAESALAELRSVFRRHDNKQNIEQEIHTAIGKTEHDFAADEISLKFIEQYIASEHALKKVQL 363
               |...:..|.:            ||             ||:.:.|  |:.:..:| |.:...:
Mouse   308 ---PDGQSAQEAK------------EQ-------------AAEGVDL--IKVFAKTE-AQRGAYI 341

  Fly   364 ELAVQTLKEV 373
            |||:||.:|:
Mouse   342 ELALQTYQEI 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpS22	NP_524537.1	MRP-S22	41..282	CDD:287247	84/241 (35%)
Mrps22	NP_079761.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	40..65
Mrps22	NP_079761.1	MRP-S22	67..307	CDD:287247	84/241 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834625
Domainoid	1	1.000	157	1.000	Domainoid score	I4163
eggNOG	1	0.900	-	-		E1_KOG3890
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H57030
Inparanoid	1	1.050	157	1.000	Inparanoid score	I4267
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48815
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007406
OrthoInspector	1	1.000	-	-		oto92620
orthoMCL	1	0.900	-	-		OOG6_107905
Panther	1	1.100	-	-	LDO	PTHR13071
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4394
SonicParanoid	1	1.000	-	-		X5531
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790