Protein Alignment CG5003 and si:ch211-214j8.12

DIOPT Version :10

• Sequence 1: NP_651593.1
• Gene: CG5003 / 43344
• FlyBaseID: FBgn0039554
• Length: 713
• Species: Drosophila melanogaster
• Sequence 2: NP_001091661.1
• Gene: si:ch211-214j8.12 / 100000539
• ZFINID: ZDB-GENE-060526-102
• Length: 627
• Species: Danio rerio
• Alignment Length: 743
• Identity: 143/743 - (19%)
• Similarity: 251/743 - (33%)
• Gaps: 245/743 - (32%)

  Fly    35 PVLPQIPTEEEPEIKQRKREKEHKESLDRETECNLMDFC-------------------------- 73
            |:..|:  |..||.|.::::|...|  |.|....|:..|
Zfish     2 PLFRQL--EPTPERKSQRKKKHWTE--DEEKPSTLIGLCLQSLAENMKELWAKDYAQKYMDQYFF 62

  Fly    74 -----------DELLFEIFQYLDTSSIL--AVMH-----------------------CS---PRF 99
                       .|||.|:...|.:.::|  |.:|                       ||   .|.
Zfish    63 RYIMGPFSLLPGELLEELLCILSSRNLLTRAALHLLLLPQLSSLSLASACSLVNASLCSLIQIRC 127

  Fly   100 ENLLLDHRFYHHIDLSNGP-LPMGILEEILGRATEKTHTIKICGPPSSQHVAGEFRQFTQTLSSV 163
            :||       ..:|||... :...:|.|:|| :..:..::.:.|....|.|       ...||..
Zfish   128 QNL-------QSLDLSGSQNISASVLCELLG-SQHRLRSLSLAGTLCDQKV-------MSVLSLQ 177

  Fly   164 FPRVVQLKVLELEGVSLDFEYIHITEFPATLRRLKLKDCSVRVGDTPKSIFYSIELHLLDLEDLS 228
            .|::..|.|...         :|:|  ||.|..|..::..|...:|..|:. ::::.|.:.|..:
Zfish   178 CPKLKHLDVSRC---------LHLT--PAGLLPLAYREAHVNSTNTISSLL-ALDIGLAENEGDA 230

  Fly   229 IEDNSWFEPYYIMGLSKLPSLRRLSLKGCQALCKFVPYGSMAARFGFQKLESLDLRQTPINNSDL 293
            :...::.       |..||.|:||:::|....|..:      ....|:..|....|:      .:
Zfish   231 VSAVAFL-------LLSLPGLQRLAVEGLGQACVLI------LNREFEGTEEFTSRE------GV 276

  Fly   294 QCFSAIENLKELLLESPQILHSKQAVAKKNTNGNATDEAASPQPDSL-----KVLSDDE------ 347
            ||      ||:|.             |||..:|.::..|...:..:|     :.||.||
Zfish   277 QC------LKDLW-------------AKKTLDGRSSMSANGEERFTLEGKLDECLSLDESESRVN 322

  Fly   348 --PSTSRAAMEHLRACKVAFNLDNCSDRKEEKSPVPTEPPSEGQDLQAKRIRAPSESDDEDTSST 410
              ..||:...|.:|:..|:.|:..|.                 :|:|...:         ||...
Zfish   323 EWTGTSKECDEKVRSHIVSDNVTTCL-----------------KDVQGLSL---------DTLEA 361

  Fly   411 SGSSSDKLEVLSLP-------RNGHSNAAPLSGGV-------------------DLPPLPHAADA 449
            .|....:|.||||.       .:...:.|.|:.|:                   ||.|...|| .
Zfish   362 VGKVCPELRVLSLDCLQNIVNADSFEHGAVLARGLGRFSGQLNSLSLQFAGFLSDLVPALQAA-G 425

  Fly   450 ANAADAPIAVDAANIEAPGQSPGLD-----PRPPRAYIYVPDAENANPRQQRSVVAVFAQGTEQR 509
            :|.    :::....|:|.|.:..|:     ||.....|:: |..|:|..:.........:|....
Zfish   426 SNL----LSLSLEGIKADGHTAFLELIRACPRLTSLSIHL-DPPNSNMDEDDEDEDAEDEGRLSN 485

  Fly   510 YIYVNQQFSLPMNVLMPTRRHRTHPRPNYDQVVQHPMFWNMLEPL------DRDYARRVRPRPPS 568
            ...:....||.::..:..|:            ::.|:.|..|:.:      .....:::......
Zfish   486 LPCIPHLRSLTLHFSLDERQ------------MKPPLCWTSLKDVLWALLRGASLLQKLSLIAVP 538

  Fly   569 CQTTPQYYVTDRAMYSFGRADRPVQPDVVWIRNINRSPDNKLERLSLRNYHLITNHTLEHLVQCS 633
            |:..|.:.:.         .:.|.:|    :..::..|...|...|| |...||..|:.|:|...
Zfish   539 CRLDPVFKLV---------LNHPAKP----LDALDNPPLQCLRSASL-NRSDITMDTVVHVVNTC 589

  Fly   634 PNLVYIDVSGT-SITLPAIRRFKISKPK 660
            ..|..:|:||. .::|..|.:.: ||.|
Zfish   590 RRLSCLDLSGCWEMSLSNITKLQ-SKTK 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5003	NP_651593.1	F-box	69..111	CDD:425796	15/106 (14%)
		leucine-rich repeat	610..635	CDD:275381	9/24 (38%)
si:ch211-214j8.12	NP_001091661.1	AMN1	122..>201	CDD:187754	23/104 (22%)
		leucine-rich repeat	130..155	CDD:275381	8/32 (25%)
		leucine-rich repeat	156..180	CDD:275381	5/30 (17%)
		leucine-rich repeat	181..215	CDD:275381	10/44 (23%)
		leucine-rich repeat	216..243	CDD:275381	4/34 (12%)
		leucine-rich repeat	314..368	CDD:275381	14/79 (18%)
		leucine-rich repeat	403..427	CDD:275381	5/24 (21%)
		leucine-rich repeat	428..453	CDD:275381	4/28 (14%)