Protein Alignment Mtl and RHO4

DIOPT Version :10

• Sequence 1: NP_524533.1
• Gene: Mtl / 43319
• FlyBaseID: FBgn0039532
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: NP_012981.3
• Gene: RHO4 / 853929
• SGDID: S000001763
• Length: 291
• Species: Saccharomyces cerevisiae
• Alignment Length: 227
• Identity: 91/227 - (40%)
• Similarity: 121/227 - (53%)
• Gaps: 46/227 - (20%)

  Fly     7 IKCVVVGDGTVGKTCMLISYTTDCFPGEYVPTVFDNYSAPMQVDTIQ-VSLGLWDTAGQEDYDRL 70
            :|.||||||.|||||:||||....||.:|:||:|:||...::....| :.|.||||||||:|.||
Yeast    73 LKIVVVGDGAVGKTCLLISYVQGTFPTDYIPTIFENYVTNIEGPNGQIIELALWDTAGQEEYSRL 137

  Fly    71 RPLSYPQTDVFLICYSVASPSSFENVTSKWYPEIKHHCPDAPIILVGTKIDLREDRETLSGLAEQ 135
            |||||...||.::||||.|.:|.:||...|:||:||.||..||:|||.|.||.| .:.||.|.|.
Yeast   138 RPLSYTNADVLMVCYSVGSKTSLKNVEDLWFPEVKHFCPSTPIMLVGLKSDLYE-ADNLSDLVEP 201

  Fly   136 GLTPLKREQGQKLANKIRAVKYMECSALTQRGLKPVFEEAVRAVLR-------------PEPLKR 187
                   ...:.||.::.|..:::|||..:..:..|||.|:..:|.             ..|.||
Yeast   202 -------SSAESLAKRLGAFAHIQCSARLKENIDEVFETAIHTLLSDSLYAPREPTHTIKNPFKR 259

  Fly   188 ------------------------RQRKCLIM 195
                                    |:.||:||
Yeast   260 NTTRSDIDSSTGDTSVSISGTKRLRKNKCIIM 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mtl	NP_524533.1	RHO	9..182	CDD:197554	82/186 (44%)
RHO4	NP_012981.3	Rho4_like	70..248	CDD:206704	83/182 (46%)