Protein Alignment Tusp and tulp1

DIOPT Version :10

• Sequence 1: NP_001263014.1
• Gene: Tusp / 43317
• FlyBaseID: FBgn0039530
• Length: 1433
• Species: Drosophila melanogaster
• Sequence 2: NP_001016482.1
• Gene: tulp1 / 549236
• XenbaseID: XB-GENE-5732938
• Length: 516
• Species: Xenopus tropicalis
• Alignment Length: 561
• Identity: 124/561 - (22%)
• Similarity: 206/561 - (36%)
• Gaps: 164/561 - (29%)

  Fly   988 LVDKKRNRRKRQQQED-ARRHKLQQTGKSK---SLDSCDLLSLQTKLSSKEHE-----QVVRKLQ 1043
            :...|:.::|.:.||. .:..|:.:..|.|   .|||.|......||..|:.|     :..:|.:
 Frog     1 MASSKKIKKKSEGQEPITQTEKVSKKSKGKKGEDLDSEDQNQATKKLKKKKSEATQDKEGAQKSK 65

  Fly  1044 EISDSS--ACSSAANTL--CFKCRNN--MSPSSACKRCQPSASSVLDEITAVVPAVEPAKESPAV 1102
            |.:..|  |.|.:.:|.  ..|.:.|  :|..:|.|..:....|              ..||...
 Frog    66 EATSKSKEATSKSKDTAKETSKGKKNIGLSRFNASKTSKQRLGS--------------EGESEEE 116

  Fly  1103 QAKPAPKKRFDVITSFTDSPLFTRKHRFGIGRSKET--AGTENSTPLLGRKQDNGFSFVKQLSEV 1165
            :|...|||:     ..::|          ...||||  .|.||.:.             |:.::.
 Frog   117 EAPKKPKKK-----GSSES----------TSESKETKQKGDENKSE-------------KKNAKA 153

  Fly  1166 RWRRKEQPAQAQVNGSSNASTLERQPQPEITGAACGTVEATPVEAKASVSLHTQALTTLENIISR 1230
            :.:::|..:..|:||........::.|    |.|....::.....|::....|....|..::...
 Frog   154 KDKKRESGSMFQINGGKKEEKNIKKGQ----GNADKDSDSNSKPLKSTKKRATSMFQTKGDVSKD 214

  Fly  1231 LRDLDEGRL---TPPSTPQRLPRSSPASPAASKKNKRQQSN--SPIRHILN--------SP---- 1278
            ::...:|..   ......:.|.:::.......||:|:::..  ||:..:.|        :|
 Frog   215 VKGKKKGLAKSNEEEEEEEELTKNTNKKGKRGKKSKKKEERPVSPVIEVDNLEEFVLRPAPQGVT 279

  Fly  1279 -------------------------------LLNRRQRKKQSI------IESSDDEGNQTNGSGE 1306
                                           ||..|:|||...      |:::|......|..|:
 Frog   280 IKCKVTRDKKGMDRGLYPTYYVHLDNDKKVFLLAGRKRKKSKTSNYLISIDATDLSRGGENFIGK 344

  Fly  1307 -ESNNAG-------NGKQYRDLETFQKAQLRQKL----------------KRGKIEPNGSASCAN 1347
             .||..|       ||.. .|......:.:||:|                |...:.|.....|..
 Frog   345 LRSNLMGTKFTVFDNGAS-PDKANSDWSNVRQELAAIVYETNVLGFKGPRKMTVLIPGMDEDCER 408

  Fly  1348 PAPVRRE------------------FVMHNKAPMWNEMSQVYQLDFGGRVTQESAKNFQIEFRGK 1394
             .|||..                  ..:|||:|:||:.:|.|.|:|.||||..|.|||||.....
 Frog   409 -VPVRPRNDNDGLLQRWQNKNMENLIQLHNKSPVWNDETQSYVLNFHGRVTHPSVKNFQIVHADD 472

  Fly  1395 Q---VMQFGRIDGNAYTLDFQYPFSALQAFAVALANVTQRL 1432
            .   :|||||:..:|:|:|::||..|:||||:||::...:|
 Frog   473 LDYIIMQFGRVADDAFTMDYKYPMCAVQAFAIALSSFDGKL 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tusp	NP_001263014.1	WD40	<81..221	CDD:441893
		WD40 repeat	91..126	CDD:293791
		WD40 repeat	132..168	CDD:293791
		WD40 repeat	173..208	CDD:293791
		WD40 repeat	216..263	CDD:293791
		WD40 repeat	270..333	CDD:293791
		Tub	<1249..1426	CDD:460094	68/272 (25%)
tulp1	NP_001016482.1	Tub	271..511	CDD:460094	63/241 (26%)