Protein Alignment CG42534 and ZK792.4

DIOPT Version :10

• Sequence 1: NP_651560.2
• Gene: CG42534 / 43298
• FlyBaseID: FBgn0260487
• Length: 1555
• Species: Drosophila melanogaster
• Sequence 2: NP_001023619.1
• Gene: ZK792.4 / 178102
• WormBaseID: WBGene00014077
• Length: 510
• Species: Caenorhabditis elegans
• Alignment Length: 542
• Identity: 120/542 - (22%)
• Similarity: 194/542 - (35%)
• Gaps: 145/542 - (26%)

  Fly   137 VQVLAQMREKPELLRQRDRSHRNALHYCAAQDSEGSKDLVAAASIAIAAPELLESADEDGFTPLH 201
            ||.||:.....  |..:|...:||||..|   ..|:.:::  ..:....|||.:....:|.|..|
 Worm    48 VQCLARFSNND--LLAKDTIGQNALHMAA---RVGNLNIL--KYLLDRLPELRDIQSTNGETAAH 105

  Fly   202 LAVIQGNLAMVNLLLAN--KADVNAV---DNEGHSVVHWATVCGEVE-SLRAVLAAGASVAKPDA 260
            ::...|::..:.:||..  |:.:|..   |..|.|::..||..|:.: |:..:...|.::|..|.
 Worm   106 ISAAHGDMRALEILLGGSLKSTMNCAMTRDVNGTSILMAATARGDTDMSIWLLRKFGKALALLDN 170

  Fly   261 N-GGTPLHYAAQMCGASKQDSKQQASSSNSSRLSLEILGILLSHPQSSVDVQDKDGRQPLLWAAS 324
            | ...|:|.||                   ::.::|.|...:......|:.:|:.|..|.::|..
 Worm   171 NCKMLPVHVAA-------------------AQGNIEFLRAAIKFDNQMVNARDEFGCTPCVYAVQ 216

  Fly   325 AGSAKAVIALV-KAGARVESSDKDGLTALHCAGSRGHTECIDTLIGLCGAPTDLIDSNG-CTALH 387
            .|....|..|| ||.:.:.|....|.:.||.|...||...:..::...|:...|..:|. ..|:|
 Worm   217 GGCLGTVRFLVEKARSEMGSVSNRGQSLLHIACLCGHEHIVRWILNRSGSDAILWTTNDRANAIH 281

  Fly   388 YAVTLGHADATARLLDLEADPNRQDRKGRTPAHCGCSKGQFETLKLLKERGANLWLRNAKGDLPL 452
            .|...|.....:.||:                  ..||         |:|...:.||:.:|:.|
 Worm   282 CAAYSGSVPVLSHLLN------------------AFSK---------KKRHYVMTLRDTRGNTP- 318

  Fly   453 HEAAASGRRELLEWLLAQRPKQVNTTSNDGRSLLHIAAANDYTDMCKLLLDYGADVNAVYRNSRG 517
                                             ||:||.|::.|....:|:.|||...:..|..
 Worm   319 ---------------------------------LHLAAMNNHLDAALYMLENGADPALINANGH- 349

  Fly   518 LVLTPLDGALQRGHRSTAKFLQANGGQPANKVRLSSRRTGNPFHETNATDMVRPLKYVEKEELHD 582
               :|...|..|.||...:.:.|..|    |.|.|..:.                   :.:.:||
 Worm   350 ---SPQSIAALRHHREMERLVAAYQG----KRRKSKSKK-------------------KSQSMHD 388

  Fly   583 LRSSKKYVVYLKRSDSDNGNENGKADVGDGDCSCSEQTYRKEQRLRHVCRRHKRRQLRRRTSSCG 647
            |            |...:.|.||....| |..|.|..|...|..        :||....|..|.|
 Worm   389 L------------SQFASPNPNGPISPG-GVTSYSSNTNGFETA--------ERRAFSPRELSSG 432

  Fly   648 ESKHERCSEICRSKSNIEIRRR 669
            .|.:...:|..:|::.| :|.|
 Worm   433 YSSNGDVAESIKSEAEI-VRHR 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42534	NP_651560.2	Ank_2	127..226	CDD:463710	23/93 (25%)
		ANK repeat	195..226	CDD:293786	8/35 (23%)
		ANKYR	209..514	CDD:440430	66/313 (21%)
		ANK repeat	228..259	CDD:293786	8/31 (26%)
		ANK repeat	314..345	CDD:293786	10/31 (32%)
		ANK repeat	347..379	CDD:293786	8/31 (26%)
		ANK repeat	381..412	CDD:293786	7/31 (23%)
		ANK repeat	414..479	CDD:293786	8/64 (13%)
		ANK repeat	419..445	CDD:293786	5/25 (20%)
		ANK repeat	481..511	CDD:293786	10/29 (34%)
		Ank_2	486..572	CDD:463710	21/85 (25%)
		ANK repeat	516..542	CDD:293786	6/25 (24%)
ZK792.4	NP_001023619.1	TRPV	29..>121	CDD:454755	20/79 (25%)
		ANK repeat	66..97	CDD:293786	9/35 (26%)
		ANKYR	85..366	CDD:440430	79/364 (22%)
		ANK repeat	99..135	CDD:293786	8/35 (23%)
		ANK repeat	176..204	CDD:293786	7/46 (15%)
		ANK repeat	206..238	CDD:293786	10/31 (32%)
		ANK repeat	240..273	CDD:293786	8/32 (25%)
		ANK repeat	275..312	CDD:293786	11/63 (17%)
		ANK repeat	314..345	CDD:293786	12/64 (19%)