Protein Alignment: l(3)mbt and L3MBTL4

• Sequence 1: NP_733209.1
• Gene: l(3)mbt
• FlyBaseID: FBgn0002441
• Length: 1477
• Species: Drosophila melanogaster
• Sequence 2: XP_011524059.1
• Gene: L3MBTL4
• HGNCID: 26677
• Length: 651
• Species: Homo sapiens
• Alignment Length: 722
• Identity: 225/723 (31%)
• Similarity: 323/723 (45%)
• Gaps: 144/723 (20%)

  Fly   790 RQTNYKPHKSLSAIQEQLQQ----RQKDKPRKP------------------FRWSEYLKSKGKDV 832
            :|.|.|...::.: :|:|.|    .|.::.:||                  :.|..|||.: |.|
Human     2 KQPNRKRKLNMDS-KERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKEQ-KAV 64

  Fly   833 AAPIHLFL--NPFPISPNCFEIGMKLEAIDPENCSLFCVCSIVEVRGYRLKLSFDGYSSMYDFWV 895
            |||:.||.  ..||...|.|:|||:||.|||.:.|:|||.|:.||.||||:|.||||.|.||||.
Human    65 AAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDGYLSCYDFWT 129

  Fly   896 NADSQDIFPPGWCDETARVLQAPKDYNSERFSWSRYLVKTGGKAAPRALFGHLNMQQQMDVRNGF 960
            ||.|.||.|.|||::|...|..||.|..::|.|..||.....:.||:.||  .|......:...|
Human   130 NAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLF--RNRSPNGPMSKEF 192

  Fly   961 AVGMHLEAEDLNDTGKICVATVTDILDERIRVHFDGWDDCYDLWVHITSPYIHPCGW-HEGRQQL 1024
            .|||.|||.|..:...:||||:.||:::|:.||||.|||.||.|..:.|||:.|.|| .|..:.|
Human   193 QVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVNSPYVQPVGWCQENGRTL 257

  Fly  1025 IVPPDY-QKSAFIWDDYISEVGGMAASKELFTPRQPMEYQERMKLEVVDQRNPCLIRPATVVTRK 1088
            |.|..| ....|.|.:|:......|...::|..|.|..:...|||||||:|||.|||.||:|...
Human   258 IAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNMKLEVVDKRNPRLIRVATIVDVD 322

  Fly  1089 GYRVQLHLDCWPTEYYFWLEDDSPDLHPIGWCEATSHELETPPGYLQPKSVMP----CDVEGCRG 1149
            ..||::|.|.|..:|.:|:|.||||:||||||:.|.|.||.|......| ::|    |...||||
Human   323 DQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHPLEVPQRTNDLK-ILPGQAVCPTPGCRG 386

  Fly  1150 FGNAKRFNLNVHALRECCPYAPENWRQWRSKTVKPPRVAPENIRRGWA-KKTKRACSEAKQAIKE 1213
            .|:.:....:.|.....|||:..|.::..:...:.......|:....: .|:|..||     :..
Human   387 IGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDRLREQTQANLESDSSHSKSKSLCS-----LNF 446

  Fly  1214 DSQQEIVYPKVAEVVQAKRKTSPCEEKVVKKQKQMQKE-----------------EDAEQVPDER 1261
            :.:.|.|..:...|.|||     |.:  :|.::.:..:                 |.|:||..:
Human   447 NGKHEKVNSQPRLVQQAK-----CLK--IKGKEDIDLDNLFRVLVLHPRGLEYSVEQAQQVLHQ- 503

  Fly  1262 SLAIARSFVKDYGPQFLPNYRLWQLNSAFKLDDVRTNPL-HWTSWDVCEYIERALDSTDIAKVIF 1325
              :::.|.|..:..:.||..|.........:.|:|.:.: .||..:|.|:::..|...:.||..
Human   504 --SVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQVARWTVDEVAEFVQSLLGCEEHAKCF- 565

  Fly  1326 EQDIDGRALLMLGRKELDTYLKLKVGPAVKLYSLILNLRIAVVCKFDSKNIELESNTAGPI-QRE 1389
                         :||                                     ||:..|.: ||.
Human   566 -------------KKE-------------------------------------ESSEPGCVNQRR 580

  Fly  1390 MDTPVSAIKQLPEQSQTNGYKTDHDQELSESGDDDDDEDVMLDSDDFLSVKPSCLVIDEDADGDG 1454
            ..:|.|.       ::..|        .|.|.........:..||.:.|:..|        |.||
Human   581 CSSPWSC-------AEVTG--------ASRSWGKQPTRWPLPSSDRWQSLPAS--------DTDG 622

  Fly  1455 DCESDGD 1461
            .|:||.|
Human   623 HCQSDED 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(3)mbt	NP_733209.1	MBT	822..918	CDD:214723	54/98 (55%)
		MBT	929..1028	CDD:214723	42/100 (42%)
		MBT	1038..1130	CDD:214723	43/92 (47%)
		SAM_PNT	1279..1366	CDD:280377	13/88 (15%)
L3MBTL4	XP_011524059.1	MBT	57..149	CDD:214723	53/93 (57%)
		MBT	164..260	CDD:214723	41/98 (42%)
		MBT	273..364	CDD:214723	43/91 (47%)
		zf-C2HC	379..405	CDD:279824	8/26 (31%)
		SAM_superfamily	540..>569	CDD:301707	9/80 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C86198291
eggNOG	1	0.900				E1_KOG3766
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0002641
OrthoInspector	1	1.000				T609620
orthoMCL	1	0.900				OOG5_130415
Panther	1	1.100			O	PTHR12247
Phylome	1	0.910		0.771	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R5341
TreeFam	1	0.960
User_Submission	0	0.000	Not matched by this tool.
	9	8.730